| 2012 Sparta Prague Open | |
|---|---|
 | |
| Date | 14–20 May |
| Edition | 3rd |
| Surface | Clay |
| Location | Prague Czech Republic |
| Venue | TK Sparta Praha |
| Champions | |
| Singles | |
 Lucie Šafářová | |
| Doubles | |
 Alizé Cornet / Virginie Razzano | |
The 2012 Sparta Prague Open was a professional tennis tournament played on clay courts. It was the third edition of the tournament which was part of the 2012 ITF Women's Circuit. It took place at the Tennis Club Sparta Prague in Prague, Czech Republic, from 14 to 20 May 2012.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| CZE | Lucie Šafářová | 23 | 1 |
| CZE | Klára Zakopalová | 44 | 2 |
| CZE | Barbora Záhlavová-Strýcová | 56 | 3 |
 HUN | Tímea Babos | 64 | 4 |
 GRE | Eleni Daniilidou | 65 | 5 |
 GBR | Elena Baltacha | 67 | 6 |
 JPN | Kimiko Date-Krumm | 74 | 7 |
| JPN | Ayumi Morita | 80 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry into the singles main draw as lucky losers:
Lucie Šafářová def. Klára Zakopalová 6–3, 7–5 Alizé Cornet / Virginie Razzano def. 
Akgul Amanmuradova / 
Casey Dellacqua 6–2, 6–3
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