| Singles | |
|---|---|
| 2016 Sarasota Open | |
| Champion |  Mischa Zverev |
| Runner-up |  Gerald Melzer |
| Score | 6–4, 7–6(7–2) |
Federico Delbonis was the defending champion but chose not to participate.
Mischa Zverev won the title, defeating Gerald Melzer 6–4, 7–6(7–2) in the final.
Denis Kudla (first round)
Diego Schwartzman (second round) Gerald Melzer (final)
Nikoloz Basilashvili (first round, retired) Tim Smyczek (first round) Bjorn Fratangelo (semifinals) Facundo Argüello (second round, retired) Jared Donaldson (first round)| Semifinals | Final | ||||||||||||
 Guilherme Clezar | 77 | 4 | 2r | ||||||||||
| 3 | Gerald Melzer | 64 | 6 | 3 | |||||||||
| 3 | Gerald Melzer | 4 | 62 | ||||||||||
| Mischa Zverev | 6 | 77 | |||||||||||
| 6 | Bjorn Fratangelo | 2 | 4 | ||||||||||
| Mischa Zverev | 6 | 6 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | D Kudla | 5 | 6 | 68 | |||||||||||||||||||||||
| N Rubin | 7 | 2 | 710 | N Rubin | 6 | 77 | |||||||||||||||||||||
 J Ward | 1 | 1 |  G Lama | 0 | 64 | ||||||||||||||||||||||
| G Lama | 6 | 6 | N Rubin | 3 | 0 | ||||||||||||||||||||||
| G Clezar | 7 | 6 | G Clezar | 6 | 6 | ||||||||||||||||||||||
| R Harrison | 5 | 2 | G Clezar | 79 | 6 | ||||||||||||||||||||||
| N Kicker | 6 | 6 | N Kicker | 67 | 1 | ||||||||||||||||||||||
| 8 | J Donaldson | 2 | 1 | G Clezar | 77 | 4 | 2r | ||||||||||||||||||||
| 3 | G Melzer | 6 | 1 | 6 | 3 | G Melzer | 64 | 6 | 3 | ||||||||||||||||||
| T Monteiro | 2 | 6 | 4 | 3 | G Melzer | 6 | 77 | ||||||||||||||||||||
 J McGee | 77 | 3 | 6 | J McGee | 0 | 65 | |||||||||||||||||||||
| T Paul | 65 | 6 | 4 | 3 | G Melzer | 5 | 6 | 6 | |||||||||||||||||||
| Q |  E Gómez | 3 | 6 | 2 |  Q Halys | 7 | 4 | 1 | |||||||||||||||||||
| Q Halys | 6 | 4 | 6 | Q Halys | 6 | 4 | 6 | ||||||||||||||||||||
| F Tiafoe | 6 | 6 | F Tiafoe | 1 | 6 | 3 | |||||||||||||||||||||
| 5 | T Smyczek | 4 | 3 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | B Fratangelo | 6 | 6 | ||||||||||||||||||||||||
| G Lapentti | 4 | 4 | 6 | B Fratangelo | 6 | 6 | |||||||||||||||||||||
| WC |  D Tursunov | 4 | 4 | D Novikov | 4 | 4 | |||||||||||||||||||||
| D Novikov | 6 | 6 | 6 | B Fratangelo | 6 | 6 | |||||||||||||||||||||
| Q |  P Nagy | 6 | 2 | 3 | Q | T Lipovšek Puches | 4 | 1 | |||||||||||||||||||
| Q | T Lipovšek Puches | 3 | 6 | 6 | Q | T Lipovšek Puches | 77 | 1 | 6 | ||||||||||||||||||
| G Andreozzi | 4 | G Andreozzi | 62 | 6 | 2 | ||||||||||||||||||||||
| 4 | N Basilashvili | 1r | 6 | B Fratangelo | 2 | 4 | |||||||||||||||||||||
| 7 | F Argüello | 2 | 6 | 6 | M Zverev | 6 | 6 | ||||||||||||||||||||
| WC | Connor Smith | 6 | 2 | 2 | 7 | F Argüello | 7 | 4 | 1r | ||||||||||||||||||
| M Zverev | 6 | 6 | M Zverev | 5 | 6 | 3 | |||||||||||||||||||||
| WC | S Bangoura | 3 | 1 | M Zverev | 2 | 6 | 7 | ||||||||||||||||||||
| WC | E Escobedo | 65 | 1 |  H Laaksonen | 6 | 3 | 5 | ||||||||||||||||||||
| H Laaksonen | 77 | 6 | H Laaksonen | 6 | 65 | 6 | |||||||||||||||||||||
| Q |  J Hernández | 1 | 3 | 2 | D Schwartzman | 4 | 77 | 4 | |||||||||||||||||||
| 2 | D Schwartzman | 6 | 6 | ||||||||||||||||||||||||
Juan Mónaco was the defending champion, but lost to John Isner in the semifinals.
Isner went on to win the title, defeating Nicolás Almagro in the final, 6–3, 7–5.
Dominic Thiem became the inaugural champion when Teymuraz Gabashvili retired 7–6(7–4), 5–1.
Ryan Harrison was the defending champion, but did not participate.
Mikhail Youzhny was the defending champion, but lost to Robin Haase in the quarterfinals.
Pablo Andújar won the title, defeating Juan Mónaco in the final, 6–3, 7–5.
This was the first edition of the tournament.
Gerald Melzer was the defending champion, but lost to Víctor Estrella Burgos in the semifinals. Estrella Burgos would go on to win the title defeating Damir Džumhur 7–5, 6–4 in the final.
Rajeev Ram was the defending champion, but lost in the second round to Daniel Nguyen.
Grigor Dimitrov was the defending champion, but chose not to participate this year.
Guillermo García López won the title, defeating Jiří Veselý in the final, 7–6(7–5), 7–6(13–11).
Martin Kližan was the defending champion, but withdrew before the tournament began.
Andy Murray won his first clay-court title, defeating Philipp Kohlschreiber in the final, 7–6(7–4), 5–7, 7–6(7–4).
Lukáš Rosol was the defending champion but chose not to compete.
Pablo Andújar was the defending champion, but lost to Thomaz Bellucci in the quarterfinals.
Víctor Estrella Burgos was the defending champion, but withdrew from the tournament.
Roberto Carballés Baena was the defending champion but lost in the quarterfinals to Uladzimir Ignatik.
Alexandre Sidorenko was the defending champion but chose not to defend his title.
Guido Andreozzi was the defending champion but lost in the first round to Lorenzo Giustino.
Nicolás Kicker was the defending champion but lost in the quarterfinals to Facundo Bagnis.
Andrej Martin was the defending champion but chose not to defend his title.
Lucas Pouille was the defending champion, but lost in the second round to John Millman.
Gerald Melzer was the defending champion but lost in the final to Juan Pablo Ficovich.
Roberto Bautista Agut defeated Filip Misolic in the final, 6–2, 6–2 to win the singles tennis title at the 2022 Generali Open Kitzbühel.