| Singles | |
|---|---|
| 2016 Tennis Classic of Macon | |
| Champion |  Kayla Day |
| Runner-up | Danielle Collins |
| Final score | 6–1, 6–3 |
Rebecca Peterson was the defending champion, but lost to Danielle Collins in the semifinal.
Kayla Day won the title, defeating Collins in an all-American final, 6–1, 6–3.
Samantha Crawford (second round) Jennifer Brady (second round)
Rebecca Peterson (semifinals) Grace Min (semifinals) Taylor Townsend (first round)
Barbara Haas (second round) Sachia Vickery (first round, retired) Jessica Pegula (withdrew)| Semifinals | Final | ||||||||||||
| Kayla Day | 6 | 7 | |||||||||||
| 4 | Grace Min | 2 | 5 | ||||||||||
| Kayla Day | 6 | 6 | |||||||||||
| Q | Danielle Collins | 1 | 3 | ||||||||||
| 3 | Rebecca Peterson | 2 | 0 | ||||||||||
| Q | Danielle Collins | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | S Crawford | 7 | 77 | ||||||||||||||||||||||||
 M Krajicek | 5 | 64 | 1 | S Crawford | 3 | 2 | |||||||||||||||||||||
| K Day | 6 | 6 | K Day | 6 | 6 | ||||||||||||||||||||||
| B Pera | 2 | 3 | K Day | 6 | 65 | 77 | |||||||||||||||||||||
 M Georges | 4 | 5 |  S Karatantcheva | 0 | 77 | 64 | |||||||||||||||||||||
| S Karatantcheva | 6 | 7 | S Karatantcheva | 6 | 7 | ||||||||||||||||||||||
| E Halbauer | 1 | 3 | LL | R Yurovsky | 2 | 5 | |||||||||||||||||||||
| LL | R Yurovsky | 6 | 6 | K Day | 6 | 7 | |||||||||||||||||||||
| 4 | G Min | 6 | 6 | 4 | G Min | 2 | 5 | ||||||||||||||||||||
| WC | S Santamaria | 3 | 3 | 4 | G Min | 6 | 6 | ||||||||||||||||||||
 E Ianchuk | 6 | 2 | 3 |  B Eraydın | 2 | 4 | |||||||||||||||||||||
| B Eraydın | 1 | 6 | 6 | 4 | G Min | 6 | 6 | ||||||||||||||||||||
| K Ahn | 4 | 4 | J Loeb | 2 | 3 | ||||||||||||||||||||||
| WC | D Lao | 6 | 6 | WC | D Lao | 5 | 2 | ||||||||||||||||||||
| J Loeb | 7 | 6 | J Loeb | 7 | 6 | ||||||||||||||||||||||
| 5 | T Townsend | 5 | 2 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | B Haas | 6 | 1 | 6 | |||||||||||||||||||||||
 M Larcher de Brito | 4 | 6 | 2 | 6 | B Haas | 1 | 3 | ||||||||||||||||||||
| M Oudin | 1 | 65 | A Lim | 6 | 6 | ||||||||||||||||||||||
| A Lim | 6 | 77 | A Lim | 3 | 6 | 4 | |||||||||||||||||||||
| WC | J Wacnik | 6 | 1 | 1 | 3 | R Peterson | 6 | 3 | 6 | ||||||||||||||||||
| Q | E Bektas | 4 | 6 | 6 | Q | E Bektas | 2 | 4 | |||||||||||||||||||
| Q | I Neel | 5 | 4 | 3 | R Peterson | 6 | 6 | ||||||||||||||||||||
| 3 | R Peterson | 7 | 6 | 3 | R Peterson | 2 | 0 | ||||||||||||||||||||
| 7 | S Vickery | 1 | 6 | 0r | Q | D Collins | 6 | 6 | |||||||||||||||||||
| F Di Lorenzo | 6 | 4 | 5 | F Di Lorenzo | 6 | 6 | |||||||||||||||||||||
| WC |  A Guarachi | 4 | 0 |  C Simmonds | 4 | 2 | |||||||||||||||||||||
| C Simmonds | 6 | 6 | F Di Lorenzo | 1 | 5 | ||||||||||||||||||||||
| R Anderson | 2 | 3 | Q | D Collins | 6 | 7 | |||||||||||||||||||||
| Q | D Collins | 6 | 6 | Q | D Collins | 7 | 77 | ||||||||||||||||||||
| Q | A Mueller | 1 | 2 | 2 | J Brady | 5 | 62 | ||||||||||||||||||||
| 2 | J Brady | 6 | 6 | ||||||||||||||||||||||||
Kurumi Nara was the defending champion, but chose to compete in Dubai instead.
Eugenie Bouchard was the defending champion, but chose not to participate this year.
Monica Niculescu was the defending champion, but she lost in the quarterfinals to Yanina Wickmayer.
Louisa Chirico was the defending champion, but chose to participate in Stuttgart instead.
Yanina Wickmayer was the defending champion, but lost in the first round to Viktorija Golubic.
Lesia Tsurenko was the defending champion and successfully defended her title, defeating Stefanie Vögele in the final, 5–7, 7–6(7–2), 6–2.
Johanna Konta was the defending champion, but lost in the fourth round to Venus Williams.
Beatriz Haddad Maia was the defending champion, but chose to compete at the 2018 Mutua Madrid Open instead.
Garbiñe Muguruza was the defending champion, but lost in the second round to Lesia Tsurenko.
Caroline Garcia was the defending champion but lost in the second round to Kateřina Siniaková.
Danielle Collins was the defending champion, but chose not to participate as she was still competing at the Australian Open.
Elina Svitolina was the two-time defending champion, but lost in the second round to Victoria Azarenka.
Aryna Sabalenka was the defending champion, and successfully defended her title, defeating Alison Riske in the final 6–3, 3–6, 6–1.
Caroline Wozniacki was the defending champion, but lost to Naomi Osaka in the semifinals.
Julia Görges was the two-time defending champion, but lost in the quarterfinals to Caroline Wozniacki.
The Phillip Island Trophy was a new addition to the WTA Tour in 2021.
Misaki Doi was the defending champion but chose not to participate.
Aryna Sabalenka was the defending champion, but she chose not to compete this year.
You Xiaodi was the defending champion but chose not to participate.
This was the second edition of the Adelaide International held in 2022, although this was the first time that the event was held at WTA 250 level.