Miķelis Lībietis and Dennis Novikov were the defending champions but only Lībietis chose to defend his title, partnering Tennys Sandgren. Lībietis lost in the first round to Sam Barry and Peter Kobelt.
Brian Baker and Sam Groth were the defending champions but chose not to defend their title.
Brian Baker and Mackenzie McDonald were the defending champions but only McDonald chose to defend his title, partnering Miķelis Lībietis. McDonald lost in the semifinals to Akram El Sallaly and Bernardo Oliveira.
Austin Krajicek and Tennys Sandgren were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
Marcus Daniell and Aisam-ul-Haq Qureshi were the defending champions but only Qureshi chose to defend his title, partnering Divij Sharan. Qureshi lost in the quarterfinals to Alex Bolt and Lleyton Hewitt.
Ken and Neal Skupski were the defending champions but lost in the semifinals to Frederik Nielsen and Joe Salisbury.
Bob and Mike Bryan were the defending champions, but Bob was unable to compete due to an injury. Mike played alongside James Cerretani, but lost in the first round to Scott Clayton and Joe Salisbury.
James Cerretani and Neal Skupski were the defending champions but only Skupski chose to defend his title, partnering Luke Bambridge. Skupski successfully defended his title.
Guillermo Durán and Andrés Molteni were the defending champions but chose not to defend his title.
Max Mirnyi and Philipp Oswald were the defending champions, but Mirnyi retired from professional tennis at the end of 2018 and Oswald chose to compete in Marrakesh instead.
Nick Kyrgios and Jack Sock were the defending champions, but chose not to participate this year.
Luke Bambridge and Jonny O'Mara were the defending champions but only Bambridge chose to defend his title, partnering Marcus Daniell. Bambridge lost in the semifinals to Marcel Granollers and Ben McLachlan.
Thanasi Kokkinakis and Matt Reid were the defending champions but only Reid chose to defend his title, partnering Jonny O'Mara. Reid lost in the first round to Egor Gerasimov and Li Zhe.
Luke Bambridge and Neal Skupski were the defending champions but only Bambridge chose to defend his title, partnering Ben McLachlan. Bambridge lost in the quarterfinals to Treat Huey and Adil Shamasdin.
Luke Bambridge and Jonny O'Mara were the defending champions but only O'Mara chose to defend his title, partnering Ken Skupski. O'Mara lost in the semifinals to Hans Podlipnik Castillo and Tristan-Samuel Weissborn.
Luke Bambridge and Jonny O'Mara were the defending champions but chose to defend their title with different partners. Bambridge played alongside Ben McLachlan, but lost in the first round to Wesley Koolhof and Fabrice Martin. O'Mara teamed up with Ken Skupski, but lost in the first round to Mate Pavić and Bruno Soares.
Joe Salisbury and Neal Skupski were the defending champions, but Skupski chose to compete in Basel instead.
Santiago González and Aisam-ul-Haq Qureshi were the defending champions but chose not to defend their title.
Thanasi Kokkinakis and Nick Kyrgios defeated Matthew Ebden and Max Purcell in the final, 7–5, 6–4 to win the men's doubles title at the 2022 Australian Open. They became the first all-Australian pair to win the title since Todd Woodbridge and Mark Woodforde in 1997, and the first wildcard champions in the Open Era. The final marked the first all-Australian men's doubles final at the Australian Open since 1980.
Thanasi Kokkinakis 
Jonny O'Mara 
