| Singles | |
|---|---|
| 2018 Sarasota Open | |
| Champion |  Hugo Dellien |
| Runner-up |  Facundo Bagnis |
| Final score | 2–6, 6–4, 6–2 |
Frances Tiafoe was the defending champion but chose not to defend his title.
Hugo Dellien won the title after defeating Facundo Bagnis 2–6, 6–4, 6–2 in the final.
Taro Daniel (first round)
Peter Polansky (second round)
Donald Young (second round) Mackenzie McDonald (first round)
Henri Laaksonen (quarterfinals)
Thomaz Bellucci (second round) Michael Mmoh (second round)
Blaž Rola (second round)| Semifinals | Final | ||||||||||||
| Reilly Opelka | 2r | ||||||||||||
| Facundo Bagnis | 5 | ||||||||||||
| Facundo Bagnis | 6 | 4 | 2 | ||||||||||
| Hugo Dellien | 2 | 6 | 6 | ||||||||||
| Hugo Dellien | 6 | 6 | |||||||||||
| SE | Juan Ignacio Londero | 3 | 3 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | T Daniel | 6 | 2 | 4 | |||||||||||||||||||||||
| G Clezar | 3 | 6 | 6 | G Clezar | 77 | 3 | 6 | ||||||||||||||||||||
| E King | 7 | 6 | E King | 65 | 6 | 2 | |||||||||||||||||||||
| WC | T Zink | 5 | 1 | G Clezar | 7 | 4 | 4 | ||||||||||||||||||||
| R Opelka | 4 | 77 | 7 | R Opelka | 5 | 6 | 6 | ||||||||||||||||||||
 M Kecmanović | 6 | 65 | 5 | R Opelka | 78 | 6 | |||||||||||||||||||||
 A Arnaboldi | 6 | 66 | 3 | 8 | B Rola | 66 | 3 | ||||||||||||||||||||
| 8 | B Rola | 3 | 78 | 6 | R Opelka | 2r | |||||||||||||||||||||
| 4/WC | M McDonald | 6 | 3 | 2 | F Bagnis | 5 | |||||||||||||||||||||
| Q |  J Clarke | 3 | 6 | 6 | Q | J Clarke | 62 | 6 | 77 | ||||||||||||||||||
 A Santillan | 6 | 3 | 6 | A Santillan | 77 | 4 | 61 | ||||||||||||||||||||
 D Köpfer | 3 | 6 | 2 | Q | J Clarke | 64 | 4 | ||||||||||||||||||||
| F Bagnis | 6 | 6 | F Bagnis | 77 | 6 | ||||||||||||||||||||||
| LL | J Choinski | 2 | 4 | F Bagnis | 3 | 6 | 7 | ||||||||||||||||||||
| WC | JC Aragone | 4 | 1 | 6 | T Bellucci | 6 | 4 | 5 | |||||||||||||||||||
| 6 | T Bellucci | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | M Mmoh | 6 | 6 | ||||||||||||||||||||||||
| WC | S Korda | 2 | 4 | 7 | M Mmoh | 3 | 3 | ||||||||||||||||||||
| H Dellien | 6 | 3 | H Dellien | 6 | 6 | ||||||||||||||||||||||
 C Garín | 1 | 2r | H Dellien | 5 | 6 | 78 | |||||||||||||||||||||
| M Krueger | 4 | 3 | S Kozlov | 7 | 1 | 66 | |||||||||||||||||||||
| S Kozlov | 6 | 6 | S Kozlov | 6 | 6 | ||||||||||||||||||||||
| Q | F Coria | 4 | 67 | 3 | D Young | 4 | 4 | ||||||||||||||||||||
| 3 | D Young | 6 | 79 | H Dellien | 6 | 6 | |||||||||||||||||||||
| 5 | H Laaksonen | 2 | 7 | 6 | SE | JI Londero | 3 | 3 | |||||||||||||||||||
| Q | F Dancevic | 6 | 5 | 0 | 5 | H Laaksonen | 6 | 6 | |||||||||||||||||||
| M Polmans | 6 | 6 | M Polmans | 2 | 4 | ||||||||||||||||||||||
| Q | K Uchida | 2 | 1 | 5 | H Laaksonen | 1 | 0 | ||||||||||||||||||||
| C Harrison | 4 | 1 | SE | JI Londero | 6 | 6 | |||||||||||||||||||||
| SE | JI Londero | 6 | 6 | SE | JI Londero | 6 | 6 | ||||||||||||||||||||
| SE | F Argüello | 4 | 6 | 1r | 2 | P Polansky | 4 | 3 | |||||||||||||||||||
| 2 | P Polansky | 6 | 2 | 4 | |||||||||||||||||||||||
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