| Doubles | |
|---|---|
| 2019 Tiburon Challenger | |
| Champions |  Robert Galloway  Roberto Maytín |
| Runners-up | JC Aragone  Darian King |
| Final score | 6–2, 7–5 |
Hans Hach Verdugo and Luke Saville were the defending champions [1] but only Hach Verdugo chose to defend his title, partnering Dennis Novikov. Hach Verdugo lost in the first round to Alex Lawson and Jackson Withrow.
Robert Galloway and Roberto Maytín won the title after defeating JC Aragone and Darian King 6–2, 7–5 in the final.
Marcelo Arévalo / Hunter Reese (quarterfinals) Alex Lawson / Jackson Withrow (semifinals, defaulted) Robert Galloway / Roberto Maytín (champions)
André Göransson / 
Sem Verbeek (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | M Arévalo H Reese | 6 | 6 | ||||||||||||||||||||||||
| WC | S Bangoura E King | 3 | 4 | 1 | M Arévalo H Reese | 3 | 7 | [9] | |||||||||||||||||||
| WC | U Blanch Mi Redlicki | 3 | 62 | JC Aragone D King | 6 | 5 | [11] | ||||||||||||||||||||
| JC Aragone D King | 6 | 77 | JC Aragone D King | 2 | 7 | [10] | |||||||||||||||||||||
| 4 | A Göransson S Verbeek | 3 | 77 | [7] | PR | N Pasha M Schnur | 6 | 5 | [6] | ||||||||||||||||||
| PR | N Pasha M Schnur | 6 | 60 | [10] | PR | N Pasha M Schnur | 6 | 6 | |||||||||||||||||||
T Paul  P Polansky | 0 | 1 | J Cerretani M Cressy | 3 | 4 | ||||||||||||||||||||||
| J Cerretani M Cressy | 6 | 6 | JC Aragone D King | 2 | 5 | ||||||||||||||||||||||
| JP Fruttero D Kudla | 3 | 6 | [10] | 3 | R Galloway R Maytín | 6 | 7 | ||||||||||||||||||||
| WC | H Johnson Y Johnson | 6 | 4 | [7] | JP Fruttero D Kudla | 7 | 3 | [6] | |||||||||||||||||||
| PR |  N Barrientos DE Galán | 3 | 4 | 3 | R Galloway R Maytín | 5 | 6 | [10] | |||||||||||||||||||
| 3 | R Galloway R Maytín | 6 | 6 | 3 | R Galloway R Maytín | 4 | 6 | [3] | |||||||||||||||||||
 G Escobar R Quiroz | 79 | 4 | [2] | 2 | A Lawson J Withrow | 6 | 3 | [1]d | |||||||||||||||||||
| C Eubanks M Krueger | 67 | 6 | [10] | C Eubanks M Krueger | 4 | 65 | |||||||||||||||||||||
 H Hach Verdugo D Novikov | 6 | 3 | [10] | 2 | A Lawson J Withrow | 6 | 77 | ||||||||||||||||||||
| 2 | A Lawson J Withrow | 3 | 6 | [12] | |||||||||||||||||||||||
Marcelo Arévalo and Sergio Galdós were the defending champions but chose to defend their title with different partners. Arévalo partnered Miguel Ángel Reyes-Varela and successfully defended his title. Galdós partnered Roberto Maytín but lost in the first round to Arévalo and Reyes-Varela.
Denis Kudla and Daniel Nguyen were the defending champions but chose not to defend their title.
André Göransson and Florian Lakat were the defending champions but lost in the quarterfinals to Gerard Granollers and Pedro Martínez.
Brydan Klein and Joe Salisbury were the defending champions but chose not to defend their title.
Denis Kudla and Danny Thomas were the defending champions but chose not to defend their title.
Leander Paes and Purav Raja were the defending champions but only Paes chose to defend his title, partnering Miguel Ángel Reyes-Varela. Paes lost in the quarterfinals to Alex Lawson and Jackson Withrow.
Robert Galloway and Denis Kudla were the defending champions but chose not to defend their title.
Luke Bambridge and Akira Santillan were the defending champions but chose not to defend their title.
Maxime Cressy and Bernardo Saraiva were the defending champions but lost in the quarterfinals to Roberto Maytín and Jackson Withrow.
Robert Galloway and Bradley Klahn were the defending champions but chose not to defend their title.
Robert Galloway and Roberto Maytín were the defending champions but only Maytín chose to defend his title, partnering Jackson Withrow. Maytín lost in the final to Diego Hidalgo and Martin Redlicki.
Roberto Maytín and Jackson Withrow were the defending champions but chose to defend their title with different partners. Maytín partnered Robert Galloway but lost in the first round to Filip Peliwo and Roy Smith. Withrow partnered Martin Redlicki and successfully defended his title.
Harri Heliövaara and Henri Laaksonen were the defending champions but chose not to defend their title.
Toshihide Matsui and Frederik Nielsen were the defending champions but chose not to defend their title.
Romain Arneodo and Andrei Vasilevski were the defending champions but chose not to defend their title.
Ruben Gonzales and Ruan Roelofse were the defending champions but chose to defend their title with different partners. Gonzales partnered Hunter Johnson but lost in the first round to Hans Hach Verdugo and Miguel Ángel Reyes-Varela. Roelofse partnered Christopher Rungkat but lost in the quarterfinals to William Blumberg and Max Schnur.
Mitchell Krueger and Blaž Rola were the defending champions but lost in the first round to William Blumberg and Max Schnur.
Hans Hach Verdugo and Adrián Menéndez Maceiras were the defending champions but only Hach Verdugo chose to defend his title, partnering Miguel Ángel Reyes-Varela. Hach Verdugo lost in the final to Malek Jaziri and Blaž Rola.
Karol Drzewiecki and Gonçalo Oliveira were the defending champions but chose not to defend their title.
Matthew Ebden and Max Purcell defeated Ivan and Matej Sabanov in the final, 6–3, 6–3 to win the doubles tennis title at the 2022 U.S. Men's Clay Court Championships. They did not drop a set en route to their first ATP Tour doubles title as a team.