| Singles | |
|---|---|
| 2021 Internazionali di Tennis Città di Trieste | |
| Champion |  Tomás Martín Etcheverry |
| Runner-up | Thiago Agustín Tirante |
| Score | 6–1, 6–1 |
Carlos Alcaraz was the defending champion [1] but chose not to defend his title.
Tomás Martín Etcheverry won the title after defeating Thiago Agustín Tirante 6–1, 6–1 in the final.
Damir Džumhur (semifinals)
Antoine Hoang (second round) Tomás Martín Etcheverry (champion)
Danilo Petrović (withdrew)
Alessandro Giannessi (second round) Marco Trungelliti (first round, retired)
Maximilian Marterer (semifinals) Thomas Fabbiano (first round)| Semifinals | Final | ||||||||||||
| 1 | Damir Džumhur | 3 | 3 | ||||||||||
| Q | Thiago Agustín Tirante | 6 | 6 | ||||||||||
| Q | Thiago Agustín Tirante | 1 | 1 | ||||||||||
| 3 | Tomás Martín Etcheverry | 6 | 6 | ||||||||||
| 3 | Tomás Martín Etcheverry | 7 | 7 | ||||||||||
| Q |  Timofey Skatov | 5 | 5 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | D Džumhur | 6 | 7 | ||||||||||||||||||||||||
| A Collarini | 0 | 5 | 1 | D Džumhur | 6 | 6 | |||||||||||||||||||||
| P Krstin | 6 | 6 | P Krstin | 3 | 1 | ||||||||||||||||||||||
| Q |  V Durasovic | 3 | 2 | 1 | D Džumhur | 6 | 6 | ||||||||||||||||||||
| G Zeppieri | 3 | 6 | 6 | 7 | M Marterer | 4 | 4 | ||||||||||||||||||||
| Q |  P Sakamoto | 6 | 3 | 3 | G Zeppieri | 4 | 6 | 64 | |||||||||||||||||||
| WC | L Nardi | 3 | 4 | 7 | M Marterer | 6 | 4 | 77 | |||||||||||||||||||
| 7 | M Marterer | 6 | 6 | 1 | D Džumhur | 3 | 3 | ||||||||||||||||||||
| Q | TA Tirante | 6 | 6 | Q | TA Tirante | 6 | 6 | ||||||||||||||||||||
| A Pellegrino | 3 | 1 | Q | TA Tirante | 6 | 6 | |||||||||||||||||||||
 N Serdarušić | 3 | 3 | R Bonadio | 4 | 2 | ||||||||||||||||||||||
| R Bonadio | 6 | 6 | Q | TA Tirante | 7 | 6 | |||||||||||||||||||||
| D Ajduković | 7 | 3 | 3 | LL | O Luz | 5 | 4 | ||||||||||||||||||||
| PR | J Lenz | 5 | 6 | 6 | PR | J Lenz | 5 | 0 | |||||||||||||||||||
| LL | O Luz | 4 | LL | O Luz | 7 | 6 | |||||||||||||||||||||
| 6 | M Trungelliti | 2r | |||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | A Giannessi | 4 | 6 | 6 | |||||||||||||||||||||||
| R Molleker | 6 | 2 | 1 | 5 | A Giannessi | 710 | 4 | 0 | |||||||||||||||||||
| GM Moroni | 2 | 66 |  V Sachko | 68 | 6 | 6 | |||||||||||||||||||||
| V Sachko | 6 | 78 | V Sachko | 4 | 4 | ||||||||||||||||||||||
| A Arnaboldi | 63 | 1 | 3 | TM Etcheverry | 6 | 6 | |||||||||||||||||||||
| WC |  R Haase | 77 | 6 | WC | R Haase | 6 | 0 | 4 | |||||||||||||||||||
| C Ugo Carabelli | 3 | 5 | 3 | TM Etcheverry | 4 | 6 | 6 | ||||||||||||||||||||
| 3 | TM Etcheverry | 6 | 7 | 3 | TM Etcheverry | 7 | 7 | ||||||||||||||||||||
| 8 | T Fabbiano | 3 | 4 | Q | T Skatov | 5 | 5 | ||||||||||||||||||||
| L Giustino | 6 | 6 | L Giustino | 6 | 2 | 1 | |||||||||||||||||||||
| Q | T Skatov | 7 | 5 | 6 | Q | T Skatov | 1 | 6 | 6 | ||||||||||||||||||
 D Stricker | 5 | 7 | 4 | Q | T Skatov | 65 | 6 | 78 | |||||||||||||||||||
| WC | F Cobolli | 78 | 6 | WC | F Cobolli | 77 | 1 | 66 | |||||||||||||||||||
 M Vrbenský | 66 | 3 | WC | F Cobolli | 6 | 6 | |||||||||||||||||||||
| F Meligeni Alves | 77 | 63 | 1 | 2 | A Hoang | 2 | 1 | ||||||||||||||||||||
| 2 | A Hoang | 65 | 77 | 6 | |||||||||||||||||||||||
Lý Hoàng Nam and Sumit Nagal were the defending champions, but were both ineligible to compete this year.
Cristian Garín defeated Facundo Bagnis in the final, 6–4, 6–7(3–7), 7–5 to capture the men's singles tennis title at the 2021 Chile Open.
Federico Delbonis was the defending champion but chose not to defend his title.
Yannick Hanfmann was the defending champion but chose not to defend his title.
Adrian Ungur was the defending champion when the event was last held in 2014 but chose not to defend his title as he had retired from professional tennis.
Tallon Griekspoor was the defending champion but chose not to defend his title.
Francisco Cerúndolo was the defending champion but lost in the second round to Gonçalo Oliveira.
Jaume Munar was the defending champion but lost in the semifinals to Juan Ignacio Londero.
Casper Ruud defeated the defending champion Diego Schwartzman in the final, 5–7, 6–2, 6–3 to win the singles title at the 2022 Argentina Open.
Sebastián Báez was the defending champion but chose not to defend his title.
Jenson Brooksby was the defending champion but chose not to defend his title.
Federico Coria was the defending champion but chose not to defend his title.
Cameron Norrie defeated Alex Molčan in the final, 6–3, 6–7(3–7), 6–1 to win the singles tennis title at the 2022 ATP Lyon Open. Norrie became the first Briton to win a clay court title on the ATP Tour since 2016.
Francisco Cerúndolo defeated Sebastián Báez in the final, 7–6(7–4), 6–2 to win the men's singles tennis title at the 2022 Swedish Open. It was his maiden ATP Tour title.
Tomás Martín Etcheverry was the defending champion but chose not to defend his title.
Juan Pablo Varillas was the defending champion but lost in the first round to Thiago Agustín Tirante.
Camilo Ugo Carabelli was the defending champion but lost in the second round to Giovanni Mpetshi Perricard.
Alejandro Tabilo was the defending champion but chose not to defend his title.
Hugo Dellien was the defending champion but chose not to defend his title.
Alexei Popyrin was the defending champion but chose not to defend his title.