| Doubles | |
|---|---|
| 2022 Internationaux de Tennis de Vendée | |
| Champions |  Sander Arends David Pel |
| Runners-up |  Purav Raja Divij Sharan |
| Score | 6–7(1–7), 7–6(8–6), [10–6] |
Jonathan Eysseric and Quentin Halys were the defending champions [1] but chose not to defend their title.
Sander Arends and David Pel won the title after defeating Purav Raja and Divij Sharan 6–7(1–7), 7–6(8–6), [10–6] in the final.
Ivan Sabanov / Matej Sabanov (first round) Sander Arends / David Pel (champions) Sem Verbeek / 
Szymon Walków (quarterfinals)
Fabian Fallert / Hendrik Jebens (quarterfinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | I Sabanov M Sabanov | 64 | 4 | ||||||||||||||||||||||||
 K Jacquet C Tabur | 77 | 6 | K Jacquet C Tabur | 1 | 4 | ||||||||||||||||||||||
| P Raja D Sharan | 6 | 7 | P Raja D Sharan | 6 | 6 | ||||||||||||||||||||||
| Niklas Schell Kai Wehnelt | 2 | 5 | P Raja D Sharan | 4 | 7 | [10] | |||||||||||||||||||||
| 3 | S Verbeek S Walków | 7 | 6 | T Arribagé  L Johnson | 6 | 5 | [7] | ||||||||||||||||||||
| WC | Lucas Poullain Alexandre Reco | 5 | 4 | 3 | S Verbeek S Walków | 6 | 3 | [4] | |||||||||||||||||||
| T Arribagé L Johnson | 6 | 6 | T Arribagé L Johnson | 2 | 6 | [10] | |||||||||||||||||||||
 Jac Vance Jam Vance | 2 | 3 | P Raja D Sharan | 77 | 66 | [6] | |||||||||||||||||||||
 P Milushev R Shandarov | 1 | 4 | 2 | S Arends D Pel | 61 | 78 | [10] | ||||||||||||||||||||
 V Durasovic  P Niklas-Salminen | 6 | 6 | V Durasovic P Niklas-Salminen | 77 | 3 | [10] | |||||||||||||||||||||
 David Poljak V Sachko | 5 | 64 | 4 | F Fallert H Jebens | 61 | 6 | [7] | ||||||||||||||||||||
| 4 | F Fallert H Jebens | 7 | 77 | V Durasovic P Niklas-Salminen | 4 | 3 | |||||||||||||||||||||
 K Sultanov Volodymyr Uzhylovskyi | 4 | 2 | 2 | S Arends D Pel | 6 | 6 | |||||||||||||||||||||
| WC | A Cazaux A Fils | 6 | 6 | WC | A Cazaux A Fils | ||||||||||||||||||||||
| A Escoffier D Masur | 6 | 3 | [4] | 2 | S Arends D Pel | w/o | |||||||||||||||||||||
| 2 | S Arends D Pel | 4 | 6 | [10] | |||||||||||||||||||||||
Mikhail Elgin and Alexander Kudryavtsev were the defending champions but chose not to defend their title.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but chose not to defend their title.
Gong Maoxin and Zhang Ze were the defending champions but chose not to defend their title.
Markus Eriksson and André Göransson were the defending champions but only Eriksson chose to defend his title, partnering Tuna Altuna. Eriksson lost in the quarterfinals to Sander Arends and David Pel.
Andrés Artuñedo and David Pérez Sanz were the defending champions but only Artuñedo chose to defend his title, partnering Sergio Martos Gornés. Artuñedo lost in the first round to Andreas Siljeström and Andrea Vavassori.
In the doubles of the 2019 Meerbusch Challenger tennis competition, David Pérez Sanz and Mark Vervoort were the defending champions but only Vervoort chose to defend his title, partnering Íñigo Cervantes. Vervoort lost in the first round to Sander Arends and David Pel.
Ariel Behar and Enrique López Pérez were the defending champions but only López Pérez chose to defend his title, partnering Alejandro Davidovich Fokina. Davidovich Fokina and López Pérez retired in their first round match against Karol Drzewiecki and Szymon Walków.
Matt Reid and Sergiy Stakhovsky were the defending champions but chose not to defend their title.
Sander Arends and Tristan-Samuel Weissborn were the defending champions but only Weissborn chose to defend his title, partnering Antonio Šančić. Weissborn successfully defended his title after defeating Teymuraz Gabashvili and Lukáš Lacko 7–5, 6–7(5–7), [10–7] in the final.
Zdeněk Kolář and Adam Pavlásek were the defending champions but chose not to defend their title.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions but Mahut chose not to participate. Herbert partnered Jan-Lennard Struff, but they lost in the quarterfinals to Nikola Mektić and Mate Pavić.
Nicolas Mahut and Vasek Pospisil were the defending champions, but they chose not to participate.
Sander Gillé and Joran Vliegen were the reigning champions from when the tournament was last held in 2019, but chose not to defend their title.
Ruben Bemelmans and Daniel Masur were the reigning champions but only Bemelmans chose to defend his title, partnering Jonathan Eysseric. Bemelmans lost in the first round to Jonáš Forejtek and Michael Vrbenský.
Marc Polmans and Sergiy Stakhovsky were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
Martín and Pablo Cuevas were the defending champions but only Martín Cuevas chose to defend his title, partnering Luis David Martínez. Cuevas lost in the semifinals to Sander Arends and David Pel.
Lloyd Glasspool and Harri Heliövaara defeated Rohan Bopanna and Matwé Middelkoop in the final, 6–2, 6–4 to win the men's doubles tennis title at the 2022 Hamburg European Open.
Victor Vlad Cornea and Petr Nouza were the defending champions but chose to defend their title with different partners. Cornea partnered Sergio Martos Gornés but lost in the semifinals to Sander Arends and David Pel. Nouza partnered Vitaliy Sachko but lost in the first round to Cornea and Martos Gornés.
Sander Arends and David Pel were the defending champions but only Pel chose to defend his title, partnering Gijs Brouwer. Pel lost in the first round to Jérôme Kym and Joel Schwärzler.