| Singles | |
|---|---|
| 2022 LTP Charleston Pro Tennis | |
| Champion |  Taylor Townsend |
| Runner-up |  Wang Xiyu |
| Score | 6–3, 6–2 |
Claire Liu was the defending champion [1] but chose not to participate.
Taylor Townsend won the title, defeating Wang Xiyu in the final, 6–3, 6–2.
Irina Bara (quarterfinals)
Tatjana Maria (second round) Katie Volynets (quarterfinals) Hailey Baptiste (second round) Wang Xiyu (final) CoCo Vandeweghe (first round)
Lucrezia Stefanini (first round)
Katarzyna Kawa (first round)| Semifinals | Final | ||||||||||||
| 5 | Wang Xiyu | 6 | 5 | 77 | |||||||||
| Q |  Gabriela Cé | 4 | 7 | 64 | |||||||||
| 5 | Wang Xiyu | 3 | 2 | ||||||||||
| WC | Taylor Townsend | 6 | 6 | ||||||||||
| WC | Taylor Townsend | 6 | 6 | ||||||||||
| Q | Whitney Osuigwe | 3 | 1 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | I Bara | 7 | 78 | ||||||||||||||||||||||||
| Q | C Harrison | 5 | 66 | 1 | I Bara | 6 | 6 | ||||||||||||||||||||
| A Cadanțu-Ignatik | 4 | 1 | E Navarro | 2 | 1 | ||||||||||||||||||||||
| E Navarro | 6 | 6 | 1 | I Bara | 4 | 6 | 1 | ||||||||||||||||||||
| C Dolehide | 7 | 7 | 5 | Xiy Wang | 6 | 4 | 6 | ||||||||||||||||||||
| A Parks | 5 | 5 | C Dolehide | 6 | 4 | 1 | |||||||||||||||||||||
| WC |  M Zacarías | 6 | 2 | 2 | 5 | Xiy Wang | 3 | 6 | 6 | ||||||||||||||||||
| 5 | Xiy Wang | 3 | 6 | 6 | 5 | Xiy Wang | 6 | 5 | 77 | ||||||||||||||||||
| 4/WC | H Baptiste | 6 | 1 | 7 | Q | G Cé | 4 | 7 | 64 | ||||||||||||||||||
| G Min | 3 | 6 | 5 | 4/WC | H Baptiste | 6 | 4 | 4 | |||||||||||||||||||
| Q | G Cé | 6 | 7 | Q | G Cé | 4 | 6 | 6 | |||||||||||||||||||
| Q |  A Paražinskaitė | 3 | 5 | Q | G Cé | 6 | 6 | ||||||||||||||||||||
| E Bektas | 3 | 5 | Q | A Graham | 0 | 2 | |||||||||||||||||||||
| J Loeb | 6 | 7 | J Loeb | 1 | 4 | ||||||||||||||||||||||
| Q | A Graham | 6 | 66 | 6 | Q | A Graham | 6 | 6 | |||||||||||||||||||
| 8 | K Kawa | 4 | 78 | 4 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | L Stefanini | 3 | 2 | ||||||||||||||||||||||||
| SE | L Chirico | 6 | 6 | SE | L Chirico | 3 | 3 | ||||||||||||||||||||
| Q |  F Abanda | 6 | 1 | 0 | WC | T Townsend | 6 | 6 | |||||||||||||||||||
| WC | T Townsend | 1 | 6 | 6 | WC | T Townsend | 1 | 6 | 6 | ||||||||||||||||||
| R Zarazúa | 6 | 6 | 3 | K Volynets | 6 | 4 | 2 | ||||||||||||||||||||
| Q | E Halbauer | 4 | 4 | R Zarazúa | 1 | 0 | |||||||||||||||||||||
| Q | C Van Nguyen | 2 | 3 | 3 | K Volynets | 6 | 6 | ||||||||||||||||||||
| 3 | K Volynets | 6 | 6 | WC | T Townsend | 6 | 6 | ||||||||||||||||||||
| 6 | C Vandeweghe | 65 | 1 | Q | W Osuigwe | 3 | 1 | ||||||||||||||||||||
 N Hibino | 77 | 6 | N Hibino | 6 | 6 | ||||||||||||||||||||||
| WC | S Chang | 6 | 6 | WC | S Chang | 2 | 2 | ||||||||||||||||||||
| F Di Lorenzo | 2 | 2 | N Hibino | 6 | 5 | 3 | |||||||||||||||||||||
| Q | W Osuigwe | 6 | 6 | Q | W Osuigwe | 4 | 7 | 6 | |||||||||||||||||||
| R Anderson | 2 | 1 | Q | W Osuigwe | 77 | 4 | 6 | ||||||||||||||||||||
 O Govortsova | 2 | 2 | 2 | T Maria | 64 | 6 | 2 | ||||||||||||||||||||
| 2 | T Maria | 6 | 6 | ||||||||||||||||||||||||
Anna Kalinskaya and Tereza Mihalíková were the defending champions, but both players were ineligible to participate.
Anastasia Potapova was the defending champion, but chose to compete in the Ladies' Singles main draw as a qualifier, where she retired in the first round against Tatjana Maria.
Usue Maitane Arconada and Claire Liu were the defending champions, however Arconada was no longer eligible to participate in junior events. Liu partnered Taylor Johnson, but lost in the quarterfinals to María José Portillo Ramírez and Sofia Sewing.
Jada Hart and Ena Shibahara were the defending champions, but both players were ineligible to participate.
Liang En-shuo won the girls' singles title at the 2018 Australian Open, defeating Clara Burel in the final, 6–3, 6–4.
Caty McNally and Iga Świątek won the girls' doubles tennis title at the 2018 French Open, defeating Yuki Naito and Naho Sato in the final, 6–2, 7–5.
Olga Danilović and Kaja Juvan were the defending champions, but both players chose not to participate.
Amanda Anisimova was the defending champion, but was chosen to compete in the women's singles instead as a wild card losing to Taylor Townsend in the first round.
Olga Danilović and Marta Kostyuk were the defending champions, but both players chose not to participate.
Wang Xinyu and Wang Xiyu were the defending champions, but chose not to participate.
Mihaela Buzărnescu was the defending champion, but lost to Daria Kasatkina in the first round.
Wang Qiang was the defending champion, but lost in the first round to Peng Shuai.
Caroline Garcia was the defending champion, but lost in the second round to Wang Yafan.
Wang Yafan was the defending champion, but lost to compatriot Wang Xiyu in the first round.
This was the first edition of the tournament.
This was the first edition of the tournament.
Katie Swan was the defending champion but chose not to participate.
Katie Volynets was the defending champion but retired in the semifinals against Gabriela Lee.
Liudmila Samsonova defeated Kaia Kanepi in the final, 4–6, 6–3, 6–3 to win the women's singles tennis title at the 2022 Washington Open. Kanepi was aiming to win her first title since 2013, and to be the oldest player to win a WTA Tour title since Serena Williams in 2020.
Magdalena Fręch was the defending champion but lost in the quarterfinals to Wang Qiang.