| Doubles | |
|---|---|
| 2022 Lima Challenger II | |
| Champions |  Jesper de Jong Max Houkes |
| Runners-up |  Guido Andreozzi Guillermo Durán |
| Score | 7–6(8–6), 3–6, [12–10] |
Ignacio Carou and Facundo Mena were the defending champions [1] but chose not to defend their title.
Jesper de Jong and Max Houkes won the title after defeating Guido Andreozzi and Guillermo Durán 7–6(8–6), 3–6, [12–10] in the final.
Sriram Balaji / Jeevan Nedunchezhiyan (semifinals) Guido Andreozzi / Guillermo Durán (final) Facundo Díaz Acosta / 
Luis David Martínez (withdrew)
Boris Arias / Federico Zeballos (quarterfinals) Hernán Casanova / Santiago Rodríguez Taverna (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | S Balaji J Nedunchezhiyan | 7 | 4 | [11] | |||||||||||||||||||||||
 J Choinski  K Drzewiecki | 5 | 6 | [9] | 1 | S Balaji J Nedunchezhiyan | 6 | 6 | ||||||||||||||||||||
| Juan Ignaco Galarza C Ugo Carabelli |  N Milojević M Zekić | 4 | 2 | ||||||||||||||||||||||||
| N Milojević M Zekić | w/o | 1 | S Balaji J Nedunchezhiyan | 2 | 6 | [13] | |||||||||||||||||||||
| 5 | H Casanova S Rodríguez Taverna | 3 | 4 | J de Jong M Houkes | 6 | 4 | [15] | ||||||||||||||||||||
| J de Jong M Houkes | 6 | 6 | J de Jong M Houkes | 712 | 6 | ||||||||||||||||||||||
P Matuszewski  A Merino | 4 | 1 | RA Burruchaga F Comesaña | 610 | 3 | ||||||||||||||||||||||
| RA Burruchaga F Comesaña | 6 | 6 | J de Jong M Houkes | 78 | 3 | [12] | |||||||||||||||||||||
| WC | D Beretta S Galdós | 2 | 62 | 2 | G Andreozzi G Durán | 66 | 6 | [10] | |||||||||||||||||||
| WC | G Bueno I Buse | 6 | 77 | WC | G Bueno I Buse | 6 | 77 | ||||||||||||||||||||
| 4 | B Arias F Zeballos | 4 | 62 | ||||||||||||||||||||||||
| WC | G Bueno I Buse | 3 | 5 | ||||||||||||||||||||||||
| A Huertas del Pino J Panta | 4 | 79 | [5] | 2 | G Andreozzi G Durán | 6 | 7 | ||||||||||||||||||||
 D Dutra da Silva T Seyboth Wild | 6 | 67 | [10] | D Dutra da Silva T Seyboth Wild | 2 | 3 | |||||||||||||||||||||
| F Coria T Lipovšek Puches | 2 | 3 | 2 | G Andreozzi G Durán | 6 | 6 | |||||||||||||||||||||
| 2 | G Andreozzi G Durán | 6 | 6 | ||||||||||||||||||||||||
Martín Alund and Horacio Zeballos were the defending champions but Zeballos chose not to compete.
Alund partnered with Facundo Bagnis and lost in the final to compatriots Guillermo Durán and Máximo González 6–3, 6–0.
Guido Andreozzi and Máximo González were the defending champions, but they chose not to compete together. Andreozzi chose to partner with Guillermo Durán, but lost in the quarterfinals to Rafael Matos and Marcelo Zormann. González chose not to compete.
Guillermo Durán and Máximo González were the defending champions, but González chose to participate at Shenzhen instead. Durán partnered with Guido Andreozzi and won the title by defeating Facundo Bagnis and Diego Schwartzman 6–3, 6–3 in the final.
Guillermo Durán and Máximo González were the defending champions, but González chose not to play this year. Guillermo Durán played alongside Andrés Molteni and lost in the first round to Guido Andreozzi and Guido Pella.
Andrej Martin and Igor Zelenay are the defending champions, but Martin did not return to defend his title. Zelenay plays alongside Mateusz Kowalczyk, they lost already in the first round to Guido Andreozzi and Nicolás Jarry.
Daniele Bracciali and Potito Starace were the defending champions, but they decided not to participate this year.
Romain Arneodo and Fernando Romboli were the defending champions but only Romboli chose to defend his title, partnering Fabrício Neis. Romboli lost in the first round to Sergio Galdós and Federico Zeballos.
Facundo Bagnis and Ariel Behar were the defending champions but only Bagnis chose to defend his title, partnering Franco Agamenone. Bagnis lost in the first round to Sander Gillé and Joran Vliegen.
Denys Molchanov and Igor Zelenay were the defending champions but chose not to defend their title.
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions but chose not to defend their title.
Cristian Garín was the defending champion but chose not to defend his title.
Guido Andreozzi and Guillermo Durán were the defending champions but chose not to defend their title.
Guido Andreozzi and Guillermo Durán were the defending champions but chose not to defend their title.
Guido Andreozzi and Guillermo Durán were the defending champions but only Durán chose to defend his title, partnering Mariano Kestelboim. Durán lost in the first round to Facundo Mena and Camilo Ugo Carabelli.
Íñigo Cervantes and Oriol Roca Batalla were the defending champions but chose not to defend his title.
Luciano Darderi and Juan Bautista Torres were the defending champions but only Torres chose to defend his title, partnering Thiago Agustín Tirante. Torres lost in the semifinals to Román Andrés Burruchaga and Facundo Díaz Acosta.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. Meligeni Alves withdrew before his first round match due to injury.
Jesper de Jong and Bart Stevens were the defending champions but only de Jong chose to defend his title, partnering Max Houkes. De Jong and Houkes retired from their first round match against Boris Arias and Federico Zeballos.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. They withdrew before their first round match.
This was the third edition of the tournament as an ATP Challenger Tour event and the first edition since 2012.