| Doubles | |
|---|---|
| 2022 Morelos Open | |
| Champions |  JC Aragone  Adrián Menéndez Maceiras |
| Runners-up |  Nicolás Mejía  Roberto Quiroz |
| Score | 7–6(7–4), 6–2 |
Luke Saville and John-Patrick Smith were the defending champions [1] but chose not to defend their title.
JC Aragone and Adrián Menéndez Maceiras won the title after defeating Nicolás Mejía and Roberto Quiroz 7–6(7–4), 6–2 in the final.
Luis David Martínez / 
Jeevan Nedunchezhiyan (first round)
Boris Arias / Federico Zeballos (semifinals) JC Aragone / Adrián Menéndez Maceiras (champions)
Skander Mansouri / 
Michail Pervolarakis (quarterfinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | LD Martínez J Nedunchezhiyan | 3 | 4 | ||||||||||||||||||||||||
| N Mejía R Quiroz | 6 | 6 | N Mejía R Quiroz | 6 | 6 | ||||||||||||||||||||||
 S Mochizuki S Shimabukuro | 3 | 2 | |||||||||||||||||||||||||
| N Mejía R Quiroz | 4 | 6 | [10] | ||||||||||||||||||||||||
| 4 | S Mansouri M Pervolarakis | 6 | 4 | [10] | Y Bhambri S Myneni | 6 | 3 | [4] | |||||||||||||||||||
 B Lock CJ Lock | 3 | 6 | [3] | 4 | S Mansouri M Pervolarakis | 3 | 65 | ||||||||||||||||||||
 JP Ficovich Matías Zukas | 3 | 2 | Y Bhambri S Myneni | 6 | 77 | ||||||||||||||||||||||
| Y Bhambri S Myneni | 6 | 6 | N Mejía R Quiroz | 64 | 2 | ||||||||||||||||||||||
| WC |  M Sánchez  B Tomic | 3 | 2 | 3 | JC Aragone A Menéndez Maceiras | 77 | 6 | ||||||||||||||||||||
| WC | A Hernández R Pacheco Méndez | 6 | 6 | WC | A Hernández R Pacheco Méndez | 3 | 6 | [7] | |||||||||||||||||||
| A Kovacevic L Patiño | 5 | 6 | [8] | 3 | JC Aragone A Menéndez Maceiras | 6 | 4 | [10] | |||||||||||||||||||
| 3 | JC Aragone A Menéndez Maceiras | 7 | 2 | [10] | 3 | JC Aragone A Menéndez Maceiras | 4 | 6 | [10] | ||||||||||||||||||
| Alt | JS Gómez A Mendoza | 63 | 3 | 2 | B Arias F Zeballos | 6 | 3 | [6] | |||||||||||||||||||
 L Castelnuovo A Santillan | 77 | 6 | L Castelnuovo A Santillan | 6 | 3 | [4] | |||||||||||||||||||||
MF Descotte  D Istomin | 4 | 3 | 2 | B Arias F Zeballos | 3 | 6 | [10] | ||||||||||||||||||||
| 2 | B Arias F Zeballos | 6 | 6 | ||||||||||||||||||||||||
Marin Draganja and Adrián Menéndez-Maceiras are the defending champions, but Marin Draganja chose not to compete. Adrián Menéndez-Maceiras played alongside Agustín Velotti.
Rajeev Ram was the defending champion, but lost in the second round to Daniel Nguyen.
Divij Sharan and Ken Skupski were the defending champions but chose not to defend their title.
Peđa Krstin was the defending champion but lost in the first round to Caio Zampieri.
Diego Schwartzman was the defending champion, but lost in the semifinals to Marin Čilić.
Enrique López-Pérez and Jeevan Nedunchezhiyan were the defending champions but chose not to defend their title.
Purav Raja and Divij Sharan were the defending champions but chose not to defend their title.
Adrián Menéndez Maceiras was the defending champion but lost in the second round to John-Patrick Smith.
Viktor Galović was the defending champion but lost in the semifinals to Adrián Menéndez Maceiras.
Fabio Fognini was the defending champion, but lost in the second round to Jürgen Zopp.
Jaume Munar was the defending champion but chose not to defend his title.
Adrián Menéndez Maceiras and Sergiy Stakhovsky were the defending champions but withdrew before their quarterfinal match.
Lucas Pouille was the defending champion, but lost in the second round to Marcos Baghdatis.
Kevin Anderson was the defending champion, but withdrew before the tournament began because of a right elbow injury.
Adrián Menéndez Maceiras was the defending champion but lost in the third round to Lucas Miedler.
Matías Franco Descotte was the defending champion but lost in the second round to Jurij Rodionov.
Roberto Maytín and Fernando Romboli were the defending champions but only Romboli chose to defend his title, partnering Miguel Ángel Reyes-Varela.
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions but chose not to defend their title.
Nicolás Barrientos and Ernesto Escobedo were the defending champions but chose not to defend their title.
JC Aragone and Adrián Menéndez Maceiras were the defending champions but chose not to defend their title.