| Women's singles | |
|---|---|
| 2022 Slovak Open | |
| Champion |  Ana Konjuh |
| Runner-up |  Nigina Abduraimova |
| Final score | 2–6, 6–0, 7–6(7–2) |
Andreea Mitu was the defending champion [1] but chose not to participate.
Ana Konjuh won the title, defeating Nigina Abduraimova in the final, 2–6, 6–0, 7–6(7–2).
Anna Karolína Schmiedlová (quarterfinals)
Daria Snigur (quarterfinals)
Eva Lys (first round, retired) Ana Konjuh (champion) Viktória Kužmová (first round)
Jaqueline Cristian (second round) Alexandra Cadanțu-Ignatik (first round, retired) Nigina Abduraimova (final)| Semifinals | Final | ||||||||||||
| WC | Renáta Jamrichová | 65 | 1r | ||||||||||
| 4 | Ana Konjuh | 77 | 1 | ||||||||||
| 4 | Ana Konjuh | 2 | 6 | 77 | |||||||||
| 8 | Nigina Abduraimova | 6 | 0 | 62 | |||||||||
| 8 | Nigina Abduraimova | 6 | 7 | ||||||||||
 Barbora Palicová | 4 | 5 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | AK Schmiedlová | 6 | 6 | ||||||||||||||||||||||||
| C Dinu | 2 | 3 | 1 | AK Schmiedlová | 6 | 6 | |||||||||||||||||||||
| Q | K Kužmová | 6 | 4 | 6 | Q | K Kužmová | 3 | 2 | |||||||||||||||||||
 Z Sönmez | 3 | 6 | 4 | 1 | AK Schmiedlová | 4 | 4 | ||||||||||||||||||||
| WC | R Jamrichová | 7 | 6 | WC | R Jamrichová | 6 | 6 | ||||||||||||||||||||
| D Šalková | 5 | 1 | WC | R Jamrichová | 77 | 3 | 710 | ||||||||||||||||||||
| Q | D Hindová | 1 | 2 | 6 | J Cristian | 61 | 6 | 68 | |||||||||||||||||||
| 6 | J Cristian | 6 | 6 | WC | R Jamrichová | 65 | 1r | ||||||||||||||||||||
| 4 | A Konjuh | 6 | 6 | 4 | A Konjuh | 77 | 1 | ||||||||||||||||||||
| J Malečková | 3 | 2 | 4 | A Konjuh | 6 | 6 | |||||||||||||||||||||
 Di Marcinkēviča | 6 | 1 | Di Marcinkēviča | 3 | 2 | ||||||||||||||||||||||
| B Cengiz | 1 | 0r | 4 | A Konjuh | 6 | 6 | |||||||||||||||||||||
| Q | A Kučmová | 6 | 65 | 6 | N Bartůňková | 1 | 3 | ||||||||||||||||||||
| Q | E Méri | 1 | 77 | 0 | Q | A Kučmová | 4 | 1r | |||||||||||||||||||
| N Bartůňková | 6 | 5 | 6 | N Bartůňková | 6 | 3 | |||||||||||||||||||||
| 5 | V Kužmová | 3 | 7 | 3 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | N Abduraimova | 77 | 6 | ||||||||||||||||||||||||
| K Volodko | 65 | 3 | 8 | N Abduraimova | 6 | 6 | |||||||||||||||||||||
| R Šramková | 0 | 6 | 6 | R Šramková | 2 | 4 | |||||||||||||||||||||
| Q |  B Klincov | 6 | 3 | 3 | 8 | N Abduraimova | 6 | 66 | 6 | ||||||||||||||||||
| Q | A Jašková | 4 | 6 | 77 | Q |  AK Tóth | 4 | 78 | 3 | ||||||||||||||||||
| Q |  F Christie | 6 | 3 | 65 | Q | A Jašková | 3 | 1 | |||||||||||||||||||
| Q | AK Tóth | 4 | Q | AK Tóth | 6 | 6 | |||||||||||||||||||||
| 3 | E Lys | 4r | 8 | N Abduraimova | 6 | 7 | |||||||||||||||||||||
| 7 | A Cadanțu-Ignatik | 0r | B Palicová | 4 | 5 | ||||||||||||||||||||||
| WC | N Vargová | 4 | WC | N Vargová | 1 | 2 | |||||||||||||||||||||
| B Palicová | 6 | 6 | B Palicová | 6 | 6 | ||||||||||||||||||||||
 M Bondarenko | 1 | 2 | B Palicová | 1 | 6 | 6 | |||||||||||||||||||||
| PR | M Lumsden | 5 | 6 | 6 | 2 | D Snigur | 6 | 2 | 3 | ||||||||||||||||||
| WC | I Balus | 7 | 3 | 4 | PR | M Lumsden | 2 | 6 | 4 | ||||||||||||||||||
| LL |  M Ristić | 1 | 1 | 2 | D Snigur | 6 | 4 | 6 | |||||||||||||||||||
| 2 | D Snigur | 6 | 6 | ||||||||||||||||||||||||
Hsieh Su-wei was the defending champion but decided not to participate.
Donna Vekić was the defending champion, having won the event in 2012, but she chose not to participate.
Nigina Abduraimova was the defending champion, having won the event in 2013. She successfully defended her title by defeating Nao Hibino in the final, 6–3, 6–4
Yvonne Meusburger was the defending champion, but lost to Chanelle Scheepers in the second round.
Elina Svitolina was the defending champion, and successfully defended her title, defeating Bojana Jovanovski in the final 6–1, 7–6(7–2).
Donna Vekić was the defending champion, but chose not to participate this year.
Alizé Cornet was the defending champion, but lost to Anna Karolína Schmiedlová in the quarterfinals.
Elina Svitolina was the two-time defending champion, but chose not to participate this year.
Shahar Pe'er is the defending champion, but chose not to participate this year.
Nao Hibino was the defending champion, but chose to participate in Nürnberg instead.
Chang Kai-chen was the defending champion, but lost to Nigina Abduraimova in the quarterfinals.
Kristýna Plíšková won the title, defeating defending champion Nao Hibino in the final, 6–3, 2–6, 6–3.
Jana Fett was the defending champion, but lost to Lizette Cabrera in the quarterfinals.
Ksenia Lykina was the defending champion, but lost to Zarina Diyas in the quarterfinals.
Yanina Wickmayer was the defending champion, but chose not to participate this year.
Marie Bouzková and Vivian Heisen were the defending champions, having won the previous edition in 2019, however both players chose not to participate.
Ons Jabeur won the women's singles tennis title at the 2022 German Open after Belinda Bencic retired with an ankle injury from the final with the score at 6–3, 2–1.
Kateřina Siniaková defeated Elena Rybakina in the final, 6–7(4–7), 7–6(7–5), 6–4 to win the singles tennis title at the 2022 WTA Slovenia Open. It was her first singles title since 2017.
Elise Mertens defeated Alizé Cornet in the final, 6–2, 6–0 to win the singles tennis title at the 2022 Jasmin Open.
Sonay Kartal was the defending champion but chose not to participate.