| Doubles | |
|---|---|
| 2022 Zagreb Ladies Open | |
| Champions |  Anastasia Dețiuc  Katarina Zavatska |
| Runners-up |  Lina Gjorcheska  Irina Khromacheva |
| Final score | 6–4, 6–7(5–7), [11–9] |
Barbara Haas and Katarzyna Kawa were the defending champions [1] but chose not to participate.
Anastasia Dețiuc and Katarina Zavatska won the title, defeating Lina Gjorcheska and Irina Khromacheva in the final, 6–4, 6–7(5–7), [11–9].
Julia Lohoff / Renata Voráčová (withdrew)
Xenia Knoll / 
Andreea Mitu (semifinals) Lina Gjorcheska / Irina Khromacheva (final)
Adrienn Nagy / Maria Timofeeva (first round)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| Alt |  V Erjavec N Potočnik | 6 | 6 | ||||||||||||||||||||||||
 L Bošković T Lukas | 4 | 4 | Alt | V Erjavec N Potočnik | 6 | 6 | |||||||||||||||||||||
 M Kawamura F Kozaki | 6 | 6 | M Kawamura F Kozaki | 4 | 3 | ||||||||||||||||||||||
| WC | M Dražić A Klasen | 4 | 3 | Alt | V Erjavec N Potočnik | 5 | 5 | ||||||||||||||||||||
| 4 | A Nagy M Timofeeva | 0 | 6 | [14] | A Dețiuc K Zavatska | 7 | 7 | ||||||||||||||||||||
| M Bulgaru OG Simion | 6 | 2 | [16] | M Bulgaru OG Simion | 2 | 77 | [9] | ||||||||||||||||||||
 D Papamichail  E Webley-Smith | 4 | 1 | A Dețiuc K Zavatska | 6 | 65 | [11] | |||||||||||||||||||||
| A Dețiuc K Zavatska | 6 | 6 | A Dețiuc K Zavatska | 6 | 65 | [11] | |||||||||||||||||||||
 J Fourlis  P Ormaechea | 3 | 6 | [3] | 3 | L Gjorcheska I Khromacheva | 4 | 77 | [9] | |||||||||||||||||||
| WC | L Ćirić Bagarić T Würth | 6 | 3 | [10] | WC | L Ćirić Bagarić T Würth | 3 | 4 | |||||||||||||||||||
 D Herdželaš D Jakupović | 2 | 6 | [8] | 3 | L Gjorcheska I Khromacheva | 6 | 6 | ||||||||||||||||||||
| 3 | L Gjorcheska I Khromacheva | 6 | 4 | [10] | 3 | L Gjorcheska I Khromacheva | 6 | 6 | |||||||||||||||||||
 I Gamarra Martins I Shymanovich | 6 | 6 | 2 | X Knoll A Mitu | 2 | 3 | |||||||||||||||||||||
| WC | L Ivković L Šumak | 3 | 0 | I Gamarra Martins I Shymanovich | 6 | 64 | [10] | ||||||||||||||||||||
| A-L Friedsam L Papadakis | 2 | 6 | [8] | 2 | X Knoll A Mitu | 3 | 77 | [12] | |||||||||||||||||||
| 2 | X Knoll A Mitu | 6 | 2 | [10] | |||||||||||||||||||||||
Noppawan Lertcheewakarn and Sally Peers were the defending champions, but both were ineligible to participate in the juniors.
Tímea Babos and Sloane Stephens were the defending champions, but they chose to not participate this year.
Kristýna Plíšková was the defending champion but was no longer eligible to compete as a junior.
Tímea Babos and Sloane Stephens were the defending champions; however, they didn't participate this year.
An-Sophie Mestach and Demi Schuurs were the defending champions but neither of them were eligible to participate in 2012.
Irina Khromacheva and Maryna Zanevska were the defending champions. Zanevska did not compete in the event, but Khromacheva retained her title alongside new partner Daria Gavrilova, with the Russian pair defeating Montserrat González and Beatriz Haddad Maia in the final, 4–6, 6–4, [10–8].
Mihaela Buzărnescu was the defending champion, but chose not to participate.
María-Teresa Torró-Flor won the title after defeating Cristina Mitu in the final, 6–3, 6–4.
This was a new event in the ITF Women's Circuit.
Timea Bacsinszky and Kristina Barrois were the defending champions having won the last edition in 2013, but chose not to participate.
Ons Jabeur was the defending champion, but chose not to participate.
Xenia Knoll and Petra Martić were the defending champions, but Martić chose not to participate. Knoll played alongside Maryna Zanevska, but they lost to Maria Sakkari and Sara Sorribes Tormo in the quarterfinals.
Lina Gjorcheska and Diāna Marcinkēviča were the defending champions, but Gjorcheska chose not to participate.
Kristýna Plíšková was the defending champion, but lost in the second round to Kurumi Nara.
Raluca Olaru and İpek Soylu were the defending champions, but Olaru chose to compete in Wuhan instead. Soylu played alongside Irina Khromacheva, but lost in the semifinal to Tímea Babos and Andrea Hlaváčková.
Beatriz Haddad Maia and Nadia Podoroska were the defending champions, but Haddad Maia could not participate this year due to a right wrist injury. Podoroska played alongside Mariana Duque Mariño, but lost in the final to Dalila Jakupović and Irina Khromacheva, 3–6, 4–6.
Dalila Jakupović and Nadiia Kichenok were the defending champions, but Kichenok chose to compete in Stuttgart instead. Jakupović played alongside Irina Khromacheva, but lost in the first round to Natela Dzalamidze and Anna Kalinskaya.
Alla Kudryavtseva and Katarina Srebotnik were the defending champions, but Kudryavtseva chose not to participate. Srebotnik played alongside Raquel Atawo, but lost in the quarterfinals to Irina Khromacheva and Veronika Kudermetova.
Dalila Jakupović and Irina Khromacheva were the defending champions, but withdrew due to a left eye injury sustained by Jakupović.
Dalila Jakupović and Irina Khromacheva are the defending champions, however Jakupović chose not to participate. Khromacheva was scheduled to partner countrywoman Olga Doroshina, but the pair withdrew after Khromacheva sustained a viral illness.
The 2022 Zagreb Ladies Open was a professional tennis tournament played on outdoor clay courts. It was the twelfth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Zagreb, Croatia between 25 April and 1 May 2022.