| Singles | |
|---|---|
| 2023 RD Open | |
| Champion |  Genaro Alberto Olivieri |
| Runner-up | Marco Trungelliti |
| Score | 7–5, 2–6, 6–4 |
Pedro Cachin was the defending champion [1] but chose not to defend his title.
Genaro Alberto Olivieri won the title after defeating Marco Trungelliti 7–5, 2–6, 6–4 in the final.
Federico Coria (semifinals)
Alejandro Tabilo (quarterfinals) Thiago Agustín Tirante (second round)
Flavio Cobolli (first round)
Hugo Dellien (first round)
Felipe Meligeni Alves (quarterfinals, retired) Genaro Alberto Olivieri (champion) Marco Trungelliti (final)| Semifinals | Final | ||||||||||||
| 1 | Federico Coria | 4 | 6 | 5 | |||||||||
| 7 | Genaro Alberto Olivieri | 6 | 3 | 7 | |||||||||
| 7 | Genaro Alberto Olivieri | 7 | 2 | 6 | |||||||||
| 8 | Marco Trungelliti | 5 | 6 | 4 | |||||||||
| Francisco Comesaña | 5 | 3 | |||||||||||
| 8 | Marco Trungelliti | 7 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | F Coria | 6 | 6 | ||||||||||||||||||||||||
| Q |  J Panta | 0 | 3 | 1 | F Coria | 6 | 1 | 6 | |||||||||||||||||||
| JP Ficovich | 6 | 0 | 6 | JP Ficovich | 4 | 6 | 4 | ||||||||||||||||||||
| PR | P Sakamoto | 4 | 6 | 2 | 1 | F Coria | 62 | 6 | 6 | ||||||||||||||||||
| JL Reis da Silva | 6 | 6 |  B Tomic | 77 | 2 | 3 | |||||||||||||||||||||
| Q |  J Roberts | 4 | 4 | JL Reis da Silva | 7 | 4 | 4 | ||||||||||||||||||||
| B Tomic | 6 | 6 | B Tomic | 5 | 6 | 6 | |||||||||||||||||||||
| 5 | H Dellien | 3 | 2 | 1 | F Coria | 4 | 6 | 5 | |||||||||||||||||||
| 4 | F Cobolli | 4 | 1 | 7 | GA Olivieri | 6 | 3 | 7 | |||||||||||||||||||
| M Dellien | 6 | 6 | M Dellien | 4 | 6 | 6 | |||||||||||||||||||||
| Q | M Alves | 7 | 6 | Q | M Alves | 6 | 3 | 4 | |||||||||||||||||||
| WC |  R Cid Subervi | 5 | 3 | M Dellien | 3 | 3 | |||||||||||||||||||||
| Q | Ignacio Monzón | 6 | 63 | 6 | 7 | GA Olivieri | 6 | 6 | |||||||||||||||||||
 K Uchida | 4 | 77 | 4 | Q | I Monzón | 4 | 0 | ||||||||||||||||||||
| M Pucinelli de Almeida | 2 | 6 | 2 | 7 | GA Olivieri | 6 | 6 | ||||||||||||||||||||
| 7 | GA Olivieri | 6 | 1 | 6 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | F Meligeni Alves | 6 | 710 | ||||||||||||||||||||||||
| E Ribeiro | 4 | 68 | 6 | F Meligeni Alves | 6 | 6 | |||||||||||||||||||||
| WC | P Bertran | 6 | 5 | 6 | WC | P Bertran | 1 | 3 | |||||||||||||||||||
| N Hardt | 3 | 7 | 2 | 6 | F Meligeni Alves | 4 | 0r | ||||||||||||||||||||
 G Oliveira | 4 | 0 | F Comesaña | 6 | 0 | ||||||||||||||||||||||
| F Comesaña | 6 | 6 | F Comesaña | 6 | 65 | 7 | |||||||||||||||||||||
| G Heide | 64 | 4 | 3 | TA Tirante | 1 | 77 | 5 | ||||||||||||||||||||
| 3 | TA Tirante | 77 | 6 | F Comesaña | 5 | 3 | |||||||||||||||||||||
| 8 | M Trungelliti | 6 | 6 | 8 | M Trungelliti | 7 | 6 | ||||||||||||||||||||
| P Boscardin Dias | 4 | 1 | 8 | M Trungelliti | 6 | 6 | |||||||||||||||||||||
| Q |  Joshua Sheehy | 66 | 3 | G Bueno | 3 | 4 | |||||||||||||||||||||
| G Bueno | 78 | 6 | 8 | M Trungelliti | 6 | 6 | |||||||||||||||||||||
 F Verdasco | 1 | 6 | 3 | 2 | A Tabilo | 4 | 2 | ||||||||||||||||||||
| WC | G Lama | 6 | 3 | 6 | WC | G Lama | 3 | 0 | |||||||||||||||||||
| Q | Kyle Seelig | 5 | 3 | 2 | A Tabilo | 6 | 6 | ||||||||||||||||||||
| 2 | A Tabilo | 7 | 6 | ||||||||||||||||||||||||
Roman Safiullin was the defending champion, but was ineligible to play.
Oliver Anderson won the title, defeating Jurabek Karimov in the final, 6–2, 1–6, 6–1.
Rafael Nadal defeated the two-time defending champion Kei Nishikori in the final, 6–4, 7–5 to win the singles title at the 2016 Barcelona Open. It was Nadal's record-extending ninth title at the Barcelona Open and his 49th clay court title, equaling Guillermo Vilas' record for the most titles on clay.
Reilly Opelka was the reigning champion, but was ineligible to compete this year.
Lý Hoàng Nam and Sumit Nagal were the defending champions, but were both ineligible to compete this year.
Taylor Harry Fritz was the defending champion, but is no longer eligible to compete.
Félix Auger-Aliassime and Denis Shapovalov were the defending champions, however Shapovalov withdrew due to injury. Auger-Aliassime played alongside Benjamin Sigouin, but lost in the final to Juan Carlos Aguilar and Felipe Meligeni Alves, 3–6, 6–7(4–7).
Fabio Fognini was the defending champion, but lost in the quarterfinals to lucky loser Andrey Rublev.
This was the first edition of the tournament.
This was the second of four editions of the tournament in the 2021 ATP Challenger Tour calendar.
Antonio Veić was the reigning champion but did not defend his title as he retired from professional tennis.
Santiago Rodríguez Taverna was the defending champion but lost in the quarterfinals to Genaro Alberto Olivieri.
Norbert Gombos was the defending champion but chose not to defend his title.
Jason Kubler was the defending champion but chose not to defend his title.
Juan Pablo Varillas was the defending champion but lost in the first round to Thiago Agustín Tirante.
Hugo Dellien was the defending champion but chose not to defend his title.
Igor Marcondes was the defending champion but chose not to defend his title.
Juan Bautista Torres was the defending champion but chose not to defend his title.
Francesco Maestrelli was the defending champion but chose not to defend his title.
Paul Jubb was the defending champion but chose not to defend his title.
Mariano Navone was the defending champion and successfully defended his title after defeating Andrea Pellegrino 3–6, 6–2, 6–3 in the final.