| 2024 Challenger Santa Fe | |
|---|---|
| Date | 3 – 9 June |
| Edition | 3rd |
| Surface | Clay |
| Location | Santa Fe, Argentina |
| Champions | |
| Singles | |
 Andrea Collarini | |
| Doubles | |
 Hady Habib /  Trey Hilderbrand | |
The 2024 Challenger Santa Fe was a professional tennis tournament played on clay courts. It was the third edition of the tournament which was part of the 2024 ATP Challenger Tour. It took place in Santa Fe, Argentina between 3 and 9 June 2024.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BOL | Hugo Dellien | 168 | 1 |
| BOL | Murkel Dellien | 222 | 2 |
| ARG | Santiago Rodríguez Taverna | 245 | 3 |
| LIB | Hady Habib | 259 | 4 |
 PER | Gonzalo Bueno | 276 | 5 |
 ECU | Álvaro Guillén Meza | 279 | 6 |
| ARG | Andrea Collarini | 292 | 7 |
 BRA | Pedro Sakamoto | 302 | 8 |
The following players received wildcards into the singles main draw:
Juan Estévez Alejo Lorenzo Lingua Lavallén Ezequiel MonferrerThe following player received entry into the singles main draw using a protected ranking:
The following players received entry into the singles main draw as alternates:
Diego Augusto Barreto Sánchez Wilson LeiteThe following players received entry from the qualifying draw:
Leonardo Aboian Dali Blanch Tomás Farjat Emilio Gómez Trey Hilderbrand 
Aleksandr Lobanov Andrea Collarini def. Facundo Mena 6–2, 6–3. Hady Habib / Trey Hilderbrand def. 
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