| Singles | |
|---|---|
| 2024 Santa Cruz Challenger II | |
| Champion |  Juan Manuel Cerúndolo |
| Runner-up |  Álvaro Guillén Meza |
| Score | 3–6, 6–1, 6–4 |
Camilo Ugo Carabelli was the defending champion [1] but chose not to defend his title.
Juan Manuel Cerúndolo won the title after defeating Álvaro Guillén Meza 3–6, 6–1, 6–4 in the final.
Juan Manuel Cerúndolo (champion)
Murkel Dellien (second round) Andrea Collarini (second round, retired)
Hady Habib (semifinals) Álvaro Guillén Meza (final)
Pedro Sakamoto (quarterfinals) Renzo Olivo (second round) Facundo Mena (semifinals)| Semifinals | Final | ||||||||||||
| 1 | Juan Manuel Cerúndolo | 77 | 6 | ||||||||||
| 4 | Hady Habib | 64 | 4 | ||||||||||
| 1 | Juan Manuel Cerúndolo | 3 | 6 | 6 | |||||||||
| 5 | Álvaro Guillén Meza | 6 | 1 | 4 | |||||||||
| 8 | Facundo Mena | 6 | 3 | 3 | |||||||||
| 5 | Álvaro Guillén Meza | 3 | 6 | 6 | |||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | JM Cerúndolo | 1 | 6 | 7 | |||||||||||||||||||||||
| Lautaro Midón | 6 | 1 | 5 | 1 | JM Cerúndolo | 6 | 7 | ||||||||||||||||||||
| SE | P Boscardin Dias | 4 | 2 | Q | J Pereira | 4 | 5 | ||||||||||||||||||||
| Q | J Pereira | 6 | 6 | 1 | JM Cerúndolo | 6 | 6 | ||||||||||||||||||||
| H Casanova | 6 | 6 | 6 | P Sakamoto | 4 | 3 | |||||||||||||||||||||
| JL Reis da Silva | 2 | 2 | H Casanova | 3 | 77 | 63 | |||||||||||||||||||||
| V Aboian | 65 | 78 | 4 | 6 | P Sakamoto | 6 | 63 | 77 | |||||||||||||||||||
| 6 | P Sakamoto | 77 | 66 | 6 | 1 | JM Cerúndolo | 77 | 6 | |||||||||||||||||||
| 4 | H Habib | 6 | 77 | 4 | H Habib | 64 | 4 | ||||||||||||||||||||
| M Pucinelli de Almeida | 3 | 64 | 4 | H Habib | 77 | 7 | |||||||||||||||||||||
| Q |  Noah Schachter | 6 | 3 | 3 |  M Soto | 62 | 5 | ||||||||||||||||||||
| M Soto | 3 | 6 | 6 | 4 | H Habib | 77 | 4 | 7 | |||||||||||||||||||
| Q | Dali Blanch | 6 | 4 | 3 | JC Prado Ángelo | 63 | 6 | 5 | |||||||||||||||||||
| JC Prado Ángelo | 4 | 6 | 6 | JC Prado Ángelo | 6 | 3 | 6 | ||||||||||||||||||||
| WC | Agustín Eduardo Cuéllar Lorberg | 2 | 2 | 7 | R Olivo | 2 | 6 | 3 | |||||||||||||||||||
| 7 | R Olivo | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | F Mena | 78 | 6 | ||||||||||||||||||||||||
| Alt | Nicolas Zanellato | 66 | 1 | 8 | F Mena | 6 | 7 | ||||||||||||||||||||
| G Villanueva | 4 | 2 | AL Lingua Lavallén | 2 | 5 | ||||||||||||||||||||||
| AL Lingua Lavallén | 6 | 6 | 8 | F Mena | 6 | 6 | |||||||||||||||||||||
| LL | U Blanch | 65 | 4 | Q | L Aboian | 3 | 2 | ||||||||||||||||||||
| Q | Leonardo Aboian | 77 | 6 | Q | L Aboian | 6 | 1 | ||||||||||||||||||||
| WC | E Gómez | 2 | 5 | 3 | A Collarini | 3 | 2r | ||||||||||||||||||||
| 3 | A Collarini | 6 | 7 | 8 | F Mena | 6 | 3 | 3 | |||||||||||||||||||
| 5 | Á Guillén Meza | 77 | 6 | 5 | Á Guillén Meza | 3 | 6 | 6 | |||||||||||||||||||
| Alt |  Adrià Soriano Barrera | 65 | 3 | 5 | Á Guillén Meza | 7 | 62 | 6 | |||||||||||||||||||
| Q | Guido Iván Justo | 5 | 1 | JB Torres | 5 | 77 | 1 | ||||||||||||||||||||
| JB Torres | 7 | 6 | 5 | Á Guillén Meza | 6 | 4 | 6 | ||||||||||||||||||||
| WC | Raúl García | 4 | 1 | G Johns | 2 | 6 | 3 | ||||||||||||||||||||
| Garrett Johns | 6 | 6 | G Johns | 0 | 6 | 77 | |||||||||||||||||||||
| Q |  Diego Augusto Barreto Sánchez | 1 | 0 | 2 | M Dellien | 6 | 4 | 64 | |||||||||||||||||||
| 2 | M Dellien | 6 | 6 | ||||||||||||||||||||||||
Guido Andreozzi and Guillermo Durán were the defending champions but only Durán chose to defend his title, partnering Mariano Kestelboim. Durán lost in the first round to Facundo Mena and Camilo Ugo Carabelli.
Daniel Elahi Galán was the defending champion, but chose not to defend his title.
Sebastián Báez was the defending champion but chose not to defend his title.
Francisco Cerúndolo was the defending champion but chose not to defend his title.
Francisco Cerúndolo was the defending champion but chose not to defend his title.
Facundo Díaz Acosta was the defending champion but lost in the final to Juan Manuel Cerúndolo.
Camilo Ugo Carabelli was the defending champion but lost in the second round to Giovanni Mpetshi Perricard.
Hugo Dellien was the defending champion but chose not to defend his title.
Camilo Ugo Carabelli was the defending champion but chose not to defend his title.
Juan Manuel Cerúndolo was the defending champion and successfully defended his title, defeating Jesper de Jong 6–3, 2–6, 6–2 in the final.
Daniel Elahi Galán was the defending champion but chose not to defend his title.
Nicolás Jarry defeated Tomás Martín Etcheverry in the final, 6–7(5–7), 7–6(7–5), 6–2 to win the singles tennis title at the 2023 Chile Open. This was Jarry's first ATP title since 2019.
Hugo Dellien was the defending champion and successfully defended his title after defeating Thiago Seyboth Wild 3–6, 6–3, 6–3 in the final.
Paul Jubb was the defending champion but chose not to defend his title.
Jan Choinski was the defending champion but lost in the second round to Andrea Pellegrino.
Agustín Velotti was the defending champion from when the tournament was last held in 2016 but didn't defend his title as he retired from professional tennis.
Daniel Altmaier was the defending champion but chose not to defend his title.
Álvaro Guillén Meza was the defending champion but lost in the second round to Mariano Navone.
Mariano Navone was the defending champion but chose not to defend his title.
Luciano Darderi was the defending champion but chose not to defend his title.