Acute zonal occult outer retinopathy

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Acute zonal occult outer retinopathy
Other namesAZOOR
Pronunciation
  • ah-cewt zoh-nahl ock-cohlt ow-tehr reh-tin-ah-puh-thee
Specialty Ophthalmology

Acute zonal occult outer retinopathy (AZOOR) is an inflammatory retinopathy in the category of white dot syndromes typified by acute loss of one or more zones of outer retinal function associated with photopsia, minimal funduscopic changes and abnormal electroretinography findings. [1] [2] Relatively little is known about the condition.

This retinal disease was first described by Donald Gass in 1992. [3] The disease served as a major plot point in the BBC drama Second Sight , which aired from 2000 to 2001. [4]

Caucasian females in their mid-thirties appear to be most susceptible but the disease may affect anyone regardless of age, sex or race. [3] The disease mechanism is unknown but it is believed that it may be caused by a virus. [3]

References

  1. Quillen DA, Davis JB, Gottlieb JL, Blodi BA, Callanan DG, Chang TS, et al. The white dot syndromes. American Journal of Ophthalmology. 2004;137(3):538-50.
  2. Carrasco L, Ramos M, Galisteo R, Pisa D, Fresno M, Gonzalez ME. Isolation of Candida famata from a Patient with Acute Zonal Occult Outer Retinopathy. J Clin Microbiol. 2005;43(2):635-40.
  3. 1 2 3 "AZOOR". American Academy of Ophthalmology.Hugo R. Salcedo, MD, Koushik Tripathy, MD (AIIMS), FRCS (Glasgow) and Vinay A. Shah M.D.
  4. "See No Evil: Detective's New Insight". New York Times. September 26, 1999.