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E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as repressors: E2F3b, E2F4-8. All of them are involved in the cell cycle regulation and synthesis of DNA in mammalian cells. E2Fs as TFs bind to the TTTCCCGC consensus binding site in the target promoter sequence.
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Yolonda Lorig Colson is an American thoracic surgeon, working in Boston, who was the 103rd president and first female president of the American Association for Thoracic Surgery (AATS), succeeding Shaf Keshavjee, MD and preceding Lars G. Svensson, MD, PhD. Colson is the Chief of the Division of Thoracic Surgery at Massachusetts General Hospital, Hermes C. Grillo Professor in Thoracic Surgery, and Professor of Surgery at Harvard Medical School. Colson is an Officer and Exam Chair for the American Board of Thoracic Surgery. She is also a collaborator of the Grinstaff Group.
References
- ↑ "Finding a Board Certified Thoracic Surgeon". www.abts.org. American Board of Thoracic Surgery.
- ↑ Brook, Adam (1996). E2F is required for G1 S progression of proliferating cells and normal morphology and survival of post-mitotic, differentiating cells. Cambridge: Harvard University. pp. 1–57.
- ↑ "Adam Brook CTSNet". www.ctsnet.org. The Cardiothoracic Surgery Network.
- ↑ Brook, Adam (1998). E2F functions and pathways. Cambridge: Harvard University. pp. 1–124.
- ↑ "Adam Brook | LinkedIn". LinkedIn. Retrieved 13 April 2015.
- ↑ "Adam Brook, M.D., Ph.D., Thoracic Surgeon". www.adambrook.com. Adam Brook, M.D., Ph.D.
- ↑ Brook, A; Xie, J; Du, W; Dyson, N (1996). "Requirements for dE2F function in proliferating cells and in post-mitotic differentiating mammalian cells". EMBO J. 15 (14): 3676–83. doi:10.1002/j.1460-2075.1996.tb00737.x. PMC 452016 . PMID 8670871.
- ↑ Boulton, S; Brook, A; Staehling-Hampton, K; Heitzler, P; Dyson, N (2000). "A role for Ebi in neuronal cell cycle control". EMBO J. 19 (20): 5376–86. doi:10.1093/emboj/19.20.5376. PMC 314025 . PMID 11032805.
- ↑ Brook, A; Zhang, C (2013). "The role of personal attributes in the genesis and progression of lung disease and cigarette smoking". Am J Public Health. 103 (5): 931–7. doi:10.2105/AJPH.2012.300748. PMC 3530664 . PMID 22994182.
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