Vasquez split his 2018 minor league season between Fort Myers, the Double-AChattanooga Lookouts, and the Triple-ARochester Red Wings. In 40 appearances for the three affiliates, he accumulated a 1–2 record with a 1.30 ERA and 108 strikeouts across 69+1⁄3 innings.[2]
On September 1, 2018, Vasquez was selected to the 40-man roster and promoted to the major leagues for the first time.[4] In nine appearances during his rookie campaign, Vasquez compiled a 1-0 record and 5.40 ERA with seven strikeouts across five innings of work.[2]
Vasquez made one appearance for Minnesota, allowing three runs without recording an out against the New York Mets on April 10, 2019. On July 4, he was removed from the 40-man roster and sent outright to Triple-A Rochester.[5] In his minor league season, Vasquez spent time with the GCL Twins, the Double-A Pensacola Blue Wahoos, and Rochester, registering a cumulative 2-3 record and 5.40 ERA with 51 strikeouts in 36+2⁄3 innings pitched across 30 appearances.[6]
Vasquez did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.[7] He returned to action in 2021 with the Triple-A St. Paul Saints, and posted a 4-0 record with a 3.61 ERA and 68 strikeouts in 42+1⁄3 innings pitched across 33 appearances.[6]
Los Angeles Dodgers
On August 31, 2021, Vasquez was traded to the Los Angeles Dodgers in exchange for Stevie Berman.[8] He was added to the major league roster on September 2.[9] Vasquez only pitched 1+2⁄3 innings for Los Angeles, appearing in two games. He allowed one run on one hit while striking out three batters in those games.[10] Vasquez also pitched six innings for the Triple-A Oklahoma City Dodgers and allowed two runs on six hits.[6] On November 30, Vasquez was non-tendered by the Dodgers, making him a free agent.[11]
Toronto Blue Jays
On March 15, 2022, Vasquez signed a one-year, $800,000 contract with the Toronto Blue Jays.[12] He posted an 8.10 ERA with six strikeouts in 6+2⁄3 innings of relief for the team before he suffered an ankle sprain. Vasquez spent time in rehabilitation with the Triple-A Buffalo Bisons and rookie-level Florida Complex League Blue Jays.
On August 17, 2022, Vasquez was claimed off waivers by the San Francisco Giants.[15] He was designated for assignment by the team on August 31, following the promotion of Andrew Knapp.[16] Vasquez cleared waivers and was sent outright to the Triple–A Sacramento River Cats on September 1.[17] In 14 games for Sacramento, he recorded a 5–0 record and 2.20 ERA with 23 strikeouts in 16+1⁄3 innings pitched. On October 3, the Giants selected Vasquez's contract to the major league roster.[18] He logged two scoreless innings in San Francisco's season finale against the San Diego Padres, recording four strikeouts.
Philadelphia Phillies (second stint)
On November 9, 2022, Vasquez was claimed off waivers by the Philadelphia Phillies. In 2023, he made 30 appearances for Philadelphia, registering a 2.27 ERA with 34 strikeouts in 39+2⁄3 innings pitched. Despite the strong results, Vasquez was designated for assignment by the Phillies on August 2, 2023.[19]
Detroit Tigers
On August 4, 2023, Vasquez was claimed off waivers by the Detroit Tigers.[20] In 12 appearances for Detroit, he struggled to an 8.31 ERA with 9 strikeouts in 8+2⁄3 innings of work. Following the season on November 6, Vasquez was removed from the 40–man roster and sent outright to the Triple–A Toledo Mud Hens.[21][22] He elected minor league free agency the next day.[23]
On January 4, 2024, Vasquez re-signed with the Tigers on a minor league contract.[24] In 48 appearances for Toledo, he compiled a 7-3 record and 5.11 ERA with 63 strikeouts across 68+2⁄3 innings pitched. Vasquez elected free agency following the season on November 4.[25]
Tecolotes de los Dos Laredos
On February 22, 2025, Vasquez signed with the Tecolotes de los Dos Laredos of the Mexican League.[26] Vasquez made seven scoreless appearances for Dos Laredos, recording six strikeouts and three saves across 7+2⁄3 innings pitched.[27]
Los Angeles Angels
On May 6, 2025, Vasquez signed a minor league contract with the Los Angeles Angels.[28] In 12 appearances split between the rookie-level Arizona Complex League Angels and Triple-A Salt Lake Bees, he posted a 1-0 record and 5.28 ERA with 16 strikeouts across 15+1⁄3 innings pitched. Vasquez was released by the Angels organization on June 17.[29]
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