Related Research Articles
Glycogen storage disease type V, also known as McArdle's disease, is a metabolic disorder, more specifically a muscle glycogen storage disease, caused by a deficiency of myophosphorylase. Its incidence is reported as one in 100,000, roughly the same as glycogen storage disease type I.
Rhabdomyolysis is a condition in which damaged skeletal muscle breaks down rapidly. Symptoms may include muscle pains, weakness, vomiting, and confusion. There may be tea-colored urine or an irregular heartbeat. Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and may lead to kidney failure.
The trochlear nerve, also called the fourth cranial nerve or CN IV, is a motor nerve that innervates just one muscle: the superior oblique muscle of the eye, which operates through the pulley-like trochlea.
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex (DAPC). Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. It has a molecular weight of 427 kDa
In biochemistry, phosphorylases are enzymes that catalyze the addition of a phosphate group from an inorganic phosphate (phosphate+hydrogen) to an acceptor.
Peter McArdle is an English artist, member of the Stuckists art group and gallery owner.
Myoglobinuria is the presence of myoglobin in the urine, which usually results from rhabdomyolysis or muscle injury. Myoglobin is present in muscle cells as a reserve of oxygen.
Tropidolaemus wagleri is a species of venomous snake, a pitviper in the subfamily Crotalinae of the family Viperidae. The species is endemic to Southeast Asia. There are no subspecies that are recognized as being valid. It is sometimes referred to as the temple viper because of its abundance around the Temple of the Azure Cloud in Malaysia.
Myophosphorylase or glycogen phosphorylase, muscle associated (PYGM) is the muscle isoform of the enzyme glycogen phosphorylase and is encoded by the PYGM gene. This enzyme helps break down glycogen into glucose-1-phosphate, so it can be used within the muscle cell. Mutations in this gene are associated with McArdle disease, a glycogen storage disease of muscle.
The McArdle Laboratory for Cancer Research is a basic cancer research facility located on the University of Wisconsin–Madison campus in Madison, Wisconsin. It houses the university's Department of Oncology. The staff of the McArdle Laboratory numbers approximately 200. Twenty-eight faculty members lead research groups focused on various fields such as cancer virology, signal transduction, cell cycle, cancer genetics, and carcinogenesis.
Harald Jockusch is a German biologist and artist with the alias Hal Jos.
Christine Anne Orengo is a Professor of Bioinformatics at University College London (UCL) known for her work on protein structure, particularly the CATH database. Orengo serves as president of the International Society for Computational Biology (ISCB), the first woman to do so in the history of the society.
The mdx mouse is a popular model for studying Duchenne muscular dystrophy (DMD). The mdx mouse has a point mutation in its DMD gene, changing the amino acid coding for a glutamine to STOP codon. This causes the muscle cells to produce a small, nonfunctional dystrophin protein. As a result, the mouse has a mild form of DMD where there is increased muscle damage and weakness.
Anne Carla Ferguson-Smith is a mammalian developmental geneticist. She is the Arthur Balfour Professor of Genetics, Head of the Department of Genetics at the University of Cambridge and a Fellow of Darwin College, Cambridge.
Anne Jacqueline Ridley is professor of Cell Biology and Head of School for Cellular and Molecular Medicine at the University of Bristol. She was previously a professor at King's College London.
Azim Surani is a developmental biologist who has been Marshall–Walton Professor at the Wellcome Trust/Cancer Research UK Gurdon Institute at the University of Cambridge since 1992, and Director of Germline and Epigenomics Research since 2013.
E-Theses Online Service (EThOS) is a bibliographic database and union catalogue of electronic theses provided by the British Library, the National Library of the United Kingdom. As of March 2018 EThOS provides access to approximately 480,000 doctoral theses awarded by over 140 UK higher education institutions, with around 3000 new thesis records added every month.
John J. McArdle is Professor of Psychology and Gerontology at the University of Southern California (USC), where he is also director of the Unified Studies of Cognition (CogUSC) Lab. He is known for his work on quantitative research methodology and on the changes in cognitive function and personality that occur as individuals age.
Barbara Anne Croy is a Canadian reproductive immunologist and professor emerita in Biomedical and Molecular Sciences at Queen's University. From 2004 until 2016, Croy was a Canada Research Chair in Reproduction, Development and Sexual Function. In 2017, she was elected a Fellow of the Royal Society of Canada. Her research focus is on mice pregnancy and natural killer cells.
Judith Anne Blake is a computational biologist at the Jackson Laboratory and Professor of Mammalian Genetics.
References
- 1 2 Wray, Susan; Tansey, Elizabeth, eds. (2015). Women phsysiologists : centenary celebrations and beyond (PDF). London: The Physiological Society. ISBN 9780993341007. OCLC 922032986.
- ↑ McArdle, Anne. (1993). Mechanisms skeletal muscle damage in the dystrophin-deficient MDX mouse (PhD thesis). University of Liverpool. OCLC 53496566. EThOS uk.bl.ethos.385144.
