Anne Spang | |
|---|---|
 Anne Spang (2011) | |
| Born | 29 November 1967 |
| Nationality | German |
| Scientific career | |
| Fields | Biochemist/Cell Biologist |
| Institutions | Darmstadt University of Applied Sciences, Pierre-and-Marie-Curie University, University of California, Berkeley, The Friedrich Miescher Laboratory of the MPG, Biozentrum University of Basel |
Anne Spang (born 29 November 1967 in Wadern) [1] is a German Biochemist/Cell Biologist and Professor at the Biozentrum University of Basel, Switzerland.
Anne Spang studied Chemical Engineering at the University of Applied Sciences in Darmstadt and Biochemistry at the University of Paris VI, France. She received her PhD in 1996 at the Max-Planck Institute of Biochemistry in Martinsried. She was then a postdoctoral fellow at the University of California, Berkeley, USA. From 1999 to 2006 she was an Independent Research Group Leader at the Friedrich Miescher Laboratory of the Max Planck Society in Tübingen. [2] Since 2005 Anne Spang has held the position of Professor of Biochemistry and Cell Biology at the Biozentrum University of Basel. [3]
Anne Spang investigates the basics of intracellular transport. Spang gained an international reputation through her discovery of the maturation process from early to late endosomes. In the nematode, Caenorhabditis elegans, she has identified the evolutionary conserved SAND-1 protein, which serves as the switch in Rab conversion during the maturation process. [4] In addition, her research has shown that ArfGAP proteins are important for the uptake of cargo into transport vesicles and that the small GTPase Arf1 and COPI components play a role in mRNA transport and mRNA metabolism. [5] Her research findings are significant for the understanding of many diseases which are based on the location of defects in protein and mRNA in the cell, such as cystic fibrosis and lysosomal storage disorders. [6]
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. Part of the endomembrane system in the cytoplasm, it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination. It resides at the intersection of the secretory, lysosomal, and endocytic pathways. It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus.
Patrick Cramer is a German chemist, structural biologist, and molecular systems biologist. In 2020, he was honoured to be an international member of the National Academy of Sciences.
Dietmar Vestweber is a biochemist and cell biologist. He is the founding director of the Max Planck Institute for Molecular Biomedicine in Münster, Germany.
The Biozentrum of the University of Basel specializes in basic molecular and biomedical research and teaching. Research includes the areas of cell growth and development, infection biology, neurobiology, structural biology and biophysics, and computational and systems biology. With 550 employees, the Biozentrum is the largest department at the University of Basel's Faculty of Science. It is home to 32 research groups with scientists from more than 40 nations.
Guy R. Cornelis is a Belgian microbiologist.
Erich Nigg is a Swiss cell biologist.
Markus Affolter is a Swiss Developmental Biologist and Professor at the Biozentrum University of Basel, Switzerland.
Michael Nip Hall is an American-Swiss molecular biologist and professor at the Biozentrum University of Basel, Switzerland.
Tilman Schirmer is a structural biologist and Professor at the Biozentrum of the University of Basel.
Martin Spiess is a Swiss Biochemist and former professor at the Biozentrum University of Basel, Switzerland.
Dirk Bumann is a German infection biologist and professor at the Biozentrum of the University of Basel, Switzerland.
Volker Haucke is a biochemist and cell biologist. He is Director of the Leibniz-Forschungsinstitut für Molekulare Pharmakologie Berlin (FMP) Berlin and Professor of Molecular Pharmacology at the Institute for Pharmacy of the Free University of Berlin.
Susan M. Gasser is a Swiss molecular biologist. She was the Director of the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, from 2004 - 2019, where she also led a research group from 2004 until 2021. She was in parallel Professor of molecular biology at the University of Basel until April 2021. Since January 2021, Susan Gasser is Director of the ISREC Foundation, based in Lausanne, and is Professor invité at the University of Lausanne in the Department of Fundamental Microbiology. She is an expert in quantitative biology and studies epigenetic inheritance and genome stability.
David Chaim Rubinsztein FRS FMedSci is the Deputy Director of the Cambridge Institute of Medical Research (CIMR), Professor of Molecular Neurogenetics at the University of Cambridge and a UK Dementia Research Institute Professor.
Elena Conti is an Italian biochemist and molecular biologist. She serves as Director and Scientific Member of the Max Planck Institute of Biochemistry in Martinsried, Germany, where she uses structural biology and biophysical techniques to study RNA transport and RNA metabolism. Together with Elisa Izaurralde, she helped characterize proteins important for exporting mRNA out of the nucleus.
Elisa Izaurralde was an Uruguayan biochemist and molecular biologist. She served as Director and Scientific Member of the Department of Biochemistry at the Max Planck Institute for Developmental Biology in Tübingen from 2005 until her death in 2018. In 2008, she was awarded the Gottfried Wilhelm Leibniz Prize, shared with Elena Conti, for "fundamental new insights into intracellular RNA transport and RNA metabolism". Together with Conti, she helped characterize proteins important for exporting mRNA out of the nucleus and later in her career she helped elucidate mechanisms of mRNA silencing, translational repression, and mRNA decay.
Julius Brennecke is a German molecular biologist and geneticist. He is a Senior Group Leader at the Institute of Molecular Biotechnology. (IMBA) of the Austrian Academy of Sciences in Vienna.
Anne Ephrussi is a French developmental and molecular biologist. Her research is focused on the study of post-transcriptional regulations such as mRNA localization and translation control in molecular biology as well as the establishment of polarity axes in cell and developmental biology. She is head of the Developmental Biology Unit and director of the EMBL International Centre for Advanced Training (EICAT) program at the European Molecular Biology Laboratory (EMBL).
Jean Gruenberg is a Swiss biologist, and a professor at the University of Geneva. His research in the fields of cell biology and biochemistry has significantly contributed to a better understanding of the molecular mechanisms involved in the intracellular traffic within eukaryotic cells, more especially in the endolysosomal pathway.
Casper Hoogenraad is a Dutch Cell Biologist who specializes in molecular neuroscience. The focus of his research is the basic molecular and cellular mechanisms that regulate the development and function of the brain. As of January 2020, he serves as Vice President of Neuroscience at Genentech Research and Early Development.
| General | |
|---|---|
| National libraries | |
| Scientific databases | |
