Related Research Articles
The University of Pennsylvania is a private Ivy League research university in Philadelphia, Pennsylvania. It is one of nine colonial colleges and was chartered prior to the U.S. Declaration of Independence when Benjamin Franklin, the university's founder and first president, advocated for an educational institution that trained leaders in academia, commerce, and public service. Penn identifies as the fourth oldest institution of higher education in the United States, though this representation is challenged by other universities, as Franklin first convened the Board of Trustees in 1749, arguably making it the fifth oldest institution of higher education in the U.S.
Child abuse is physical, sexual, and/or psychological maltreatment or neglect of a child or children, especially by a parent or a caregiver. Child abuse may include any act or failure to act by a parent or a caregiver that results in actual or potential harm to a child and can occur in a child's home, or in the organizations, schools, or communities the child interacts with.
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. It may also appear later in life and then have a milder course of the disease. The common feature is progressive weakness of voluntary muscles, with arm, leg and respiratory muscles being affected first. Associated problems may include poor head control, difficulties swallowing, scoliosis, and joint contractures.
A number of significant scientific events occurred in 2020.
This is a list of several significant scientific events that occurred or were scheduled to occur in 2021.
The following scientific events occurred in 2022.
This article lists a number of significant events in science that have occurred in the third quarter of 2020.
The 2022 Queen's Birthday Honours are appointments by some of the 15 Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. The Birthday Honours are awarded as part of the Queen's Official Birthday celebrations during the month of June. They were announced on 1 June 2022, in anticipation of the Queen's Platinum Jubilee. They were the last honours granted by the Queen before her death on 8 September 2022.
References
- ↑ Barrett, Doreen; Bilic, Sanela; Chyung, Yung; Cote, Shaun M.; Iarrobino, Ryan; Kacena, Katherine; Kalra, Ashish; Long, Kimberly; Nomikos, George; Place, Amy; Still, James Gordon; Vrishabhendra, Leela (2021). "A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy". Advances in Therapy. 38 (6): 3203–3222. doi:10.1007/s12325-021-01757-z. ISSN 0741-238X. PMC 8189951 . PMID 33963971.
- ↑ Crawford, Thomas; Darras, Basil; Day, John; Song, Guochen; Nomikos, George; Place, Amy; Barrett, Doreen; Bilic, Sanela; O‘Neil, Janet; Kertesz, Nathalie; Cote, Shaun; Patel, Jagdish; Chyung, Yung (3 May 2022). "Apitegromab in Spinal Muscular Atrophy (SMA): An Analysis of Multiple Efficacy Endpoints in the TOPAZ Trial (P15-5.005)". Neurology. 98 (18 Supplement). ISSN 0028-3878.
- ↑ Crawford, Thomas; Place, Amy; Barrett, Doreen; Cote, Shaun; Nomikos, George; Song, Guochen; Bilic, Sanela; Kalra, Ashish; Sadanowicz, Mara; O'Neil, Janet; Iarrobino, Ryan; Kertesz, Nathalie; Chyung, Yung (2021). "Relationship of pharmacokinetics and pharmacodynamics to apitegromab efficacy in patients with later-onset spinal muscular atrophy (Types 2 and 3 SMA): Results from the TOPAZ study". Journal of the Neurological Sciences. 429: 118388. doi:10.1016/j.jns.2021.118388. S2CID 238481481.