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Apure Department Departamento del Apure | |
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| Coordinates: 8°38′N70°12′W / 8.633°N 70.200°W | |
| Country | Gran Colombia |
| District | Distrito del Norte |
| Created | 1824 |
| Dissolved | 1830 |
| Capital | Barinas |
| Population (1820) | |
• Total | 480,000 |
Apure Department was one of the departments of Gran Colombia. It was split from the Venezuela Department.
It encompassed 2 provinces - Barinas Province in the north and Achaguas Province in the south.