Babanki virus | |
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Virus classification | |
Group: | Group IV ((+)ssRNA) |
Family: | |
Genus: | |
Babanki virus (BBKV) is a member of the virus family Togaviridae of Class IV of the Baltimore classification system and the genus Alphavirus .
It has an unsegmented, positive sense, single-stranded RNA genome which is approximately 11.7kb long. In general, members of the Togaviridae have genomes which are able to be used directly as mRNA and the genome of BBKV can code for both structural and non-structural proteins. Currently, the genome of BBKV has only been partially sequenced. It has a spherical nucleocapsid which is approximately 40 nm in diameter and shows icosahedral symmetry of T=4. This nucleocapsid core is surrounded by a lipid envelope covered with glycoprotein spikes and virion particles are approximately 70 nm in diameter in total .
BBKV was first isolated in Babanki in Northwest Cameroon, Africa in 1969 and the disease is also known in Senegal and Madagascar . It is closely related to another Alphavirus, Sindbis virus and causes similar symptoms in humans like fever, arthralgia or joint pain and a rash. It is spread by an arthropod vector, typically mosquitoes of the genus Culex and in this way, may be described as an Arbovirus . Its normal host is birds .
Rubella virus (RuV) is the pathogenic agent of the disease rubella, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.
Pseudoviridae is a family of viruses, which includes the following genera:
Bwamba orthobunyavirus (BWAV) belongs to the genus Orthobunyavirus and the order Bunyavirales RNA viruses. BWAV is present in large parts of Africa, endemic in Mozambique, Tanzania and Uganda. It is transmitted to humans through mosquito bites and results in a brief benign generalised infection with headache, skin rash, diarrhea and joint pain and lasts 4–5 days. The animal reservoir of the virus includes birds, monkeys and donkeys.
The Semliki Forest virus was first isolated from mosquitoes in the Semliki Forest, Uganda by the Uganda Virus Research Institute in 1942 and described by Smithburn and Haddow. It is known to cause disease in animals including humans. It is an alphavirus found in central, eastern, and southern Africa.
Mardivirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Chickens, turkeys, and quail serve as natural hosts. There are currently five species in this genus including the type species Gallid herpesvirus 2. Diseases associated with this genus include: Marek's disease, which causes asymmetric paralysis of one or more limbs, neurological symptoms, and development of multiple lymphomas that manifest as solid tumors. Gallid herpesvirus 2 is the only one of these viruses known to be pathogenic and due to the antigenic similarity between the three viruses the other two have been used to vaccinate against Marek's disease. These viruses have double stranded DNA genomes with no RNA intermediate.
Alphavirus is a genus of RNA viruses, the sole genus in the Togaviridae family. Alphaviruses belong to group IV of the Baltimore classification of viruses, with a positive-sense, single-stranded RNA genome. There are 31 alphaviruses, which infect various vertebrates such as humans, rodents, fish, birds, and larger mammals such as horses, as well as invertebrates. Alphaviruses that could infect both vertebrates and arthropods are referred dual-host alphaviruses, while insect-specific alphaviruses such as Eilat virus and Yada yada virus are restricted to their competent arthropod vector. Transmission between species and individuals occurs mainly via mosquitoes, making the alphaviruses a member of the collection of arboviruses – or arthropod-borne viruses. Alphavirus particles are enveloped, have a 70 nm diameter, tend to be spherical, and have a 40 nm isometric nucleocapsid.
Fiji disease virus (FDV) belongs to the reoviridae family and infects plants. It is one of the few plant viruses in the Reoviridae family. The type species of the genus Fijivirus, it is the only known member of Fijivirus group 1.
Sindbis virus (SINV) is a member of the Togaviridae family, in the Alphavirus genus. The virus was first isolated in 1952 in Cairo, Egypt. The virus is transmitted by mosquitoes SINV causes sindbis fever in humans and the symptoms include arthralgia, rash and malaise. Sindbis fever is most common in Southern Africa, East Africa, Egypt, Palestine, the Philippines and parts of Australia.
The Togavirus 5′ plus strand cis-regulatory element is an RNA element which is thought to be essential for both plus and minus strand RNA synthesis.
Orthonairovirus is a genus in the family Nairoviridae of the order Bunyavirales that include viruses with circular, negative-sense single stranded RNA. It got its name from the Nairobi sheep disease that affects the gastrointestinal tracts of sheep and goats. The vast majority, and perhaps all viruses in this genus are tick-borne viruses that can have human or other vertebrate hosts.
Aspiviridae, formerly Ophioviridae, is a family of segmented negative-strand RNA viruses which infect plants. Member viruses are characterized by an elongated and highly filamentous and flexible nucleocapsid with helical symmetry. It is a monotypic taxon containing only one genus, Ophiovirus. Aspiviridae is also the only family in the order Serpentovirales, which in turn is the only order in the class Milneviricetes.
Transmissible gastroenteritis virus or Transmissible gastroenteritis coronavirus (TGEV) is a coronavirus which infects pigs. It is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the APN receptor. The virus is a member of the genus Alphacoronavirus, subgenus Tegacovirus, species Alphacoronavirus 1.
The species Lloviu cuevavirus is the taxonomic home of a virus that forms filamentous virion, Lloviu virus (LLOV). The species is included in the genus Cuevavirus. LLOV is a distant relative of the commonly known Ebola virus and Marburg virus.
Alphatristromavirus is the sole genus of viruses in the family Tristromaviridae. The thermophilic archaea of the genera Thermoproteus and Pyrobaculum serve as natural hosts. There are currently only two species in this genus: Thermoproteus tenax virus 1 and the type species Pyrobaculum filamentous virus 1 The genus was formerly classified into family Lipothrixviridae of order Ligamenvirales. However, due to lack of sequence similarity of TTV1 and PFV1 to other members of the Lipothrixviridae, genus Alphalipothrixvirus was renamed to Alphatristromavirus and moved into a separate family, the Tristromaviridae.
Quadriviridae is a family of double-stranded RNA viruses with a single genus Quadrivirus. The fungi Rosellinia necatrix serves as a natural host. The name of the group derives from the quadripartite genome of its members where in Latin quad means four. There is currently only one species in this family: the type species Rosellinia necatrix quadrivirus 1.
Entebbe bat virus is an infectious disease caused by a Flavivirus that is closely related to yellow fever.
Eilat virus (EILV) is a unique Alphavirus which is known mainly for its host range restriction generally to insects by means of RNA replication. The virus found in the Negev desert. It is incapable of infecting vertebrate cells, differentiating it from other alphaviruses.
Pneumoviridae is a family of negative-strand RNA viruses in the order Mononegavirales. Humans, cattle, and rodents serve as natural hosts. Respiratory tract infections are associated with member viruses such as human respiratory syncytial virus. There are five species in the family which are divided between the genera Metapneumovirus and Orthopneumovirus.
Middelburg virus (MIDV) is an alphavirus of the Old World Group that has likely endemic and zoonotic potential. It is of the viral family Togaviridae. It was isolated from mosquitos in 1957 in South Africa, MDIV antigens have now been found in livestock, horses, and humans.
Rio Negro virus is an alphavirus that was first isolated in Argentina in 1980. The virus was first called Ag80-663 but was renamed to Rio Negro virus in 2005. The virus is a member of the Venezuelan equine encephalitis complex (VEEC), which are a group of alphaviruses in the Americas that have the potential to emerge and cause disease. Closely related viruses include Mucambo virus and Everglades virus.