Brain Mapping Foundation

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The Brain Mapping Foundation is a neuroscience organization established in 2004 by Babak Kateb to advance cross-pollination of ideas across physical sciences into biological sciences and neuroscience. The organization provides funding to the members of the Society for Brain Mapping and Therapeutics (SBMT). One of the focuses of the foundation is to further establish and fund the National Center for NanoBioElectronics (NCNBE) to rapidly integrate nanotechnology, devices, imaging, cellular and stem cell therapy. The organization has played a significant role in President Obama's BRAIN initiative. [1] [ failed verification ] [2] [ failed verification ]

Contents

Definition of brain mapping

The study of the anatomy and function of the brain and spinal cord through the use of imaging (including intra-operative, Microscopic, Endoscopic and Multi-Modality imaging), Immunohistochemistry, Molecular & optogenetics, Stem cell and Cellular Biology, Engineering (material, electrical and biomedical), Neurophysiology and Nanotechnology (See Brain Mapping for more information).

Special projects

Currently the organization is focused on establishing Global Alliance for Nano-Bio-Electronics through its National Center for NanoBioElectronic and has shaped policies in the field of Nanoneuroscience and Nanoneurosurgery. [3] In this regard, the foundation has established significant ties with international partners and plans to launch a global consortium in Neuroscience with a specific aim of integrating nanotechnology, device, imaging and cellular therapy. [4] BMF has signed a formal consortium agreement with Dr. Charlie Teo's Cure Brain Cancer Foundation in Australia, which is focused on eradicating brain cancers. [5] [6] NCNBE has also launched a graduate training program in NanoBioElectronic, which will be offering a doctoral degree in NanoBioElectronics.

Publications

BMF has been a major supporter of the Society for Brain Mapping and Therapeutics (SBMT) annual meetings and its publications. [3] [7] The Foundation supported series of special issue publications with NeuroImage, in which members of the Society published their findings. [8] [9] [10] The articles these publications were discontinued when the Society went into partnership with PLOS ONE on the ″NeuroMapping & Therapeutics Collection″. [11] BMF also played a major role in publishing the first Textbook of Nanoneuroscience and Nanoneurosurgery. [12]

Funded projects

The foundation funds multidisciplinary translation research such as:

  1. Galaxy-Exploring Camera to Be Used in the Operating Room
  2. JPL Nanotubes Help Advance Brain Tumor Research [13]
  3. NASA's Electronic Nose May Provide Neurosurgeons with A New Weapon Against Brain Cancer [14] [15] [16] [17] [18] [19] [20]
  4. X Marks the Spot; Infrared Technology used for intraoperative Mapping of the Human Brain Tumors [21]

The Brain Mapping Foundation has been supporting annual meetings of Society for Brain Mapping and Therapeutics in the last 10 years. [22] [23] [24]

Brain Mapping Day at the US Congress

Brain Mapping Foundation in collaboration with the Society for Brain Mapping and Therapeutics (SBMT), hold the Brain Mapping Days at the US Congress and Canadian Parliament to educate policymakers about the state-of-the-art research in neuroscience. More information about the Brain Mapping Days can be found at https://web.archive.org/web/20131022180145/http://www.worldbrainmapping.org/brain-mapping-day and http://www.worldbrainmapping.org/brain-research-day.%5B%5D%5B%5D

Several notable scientists, such as Dr. Keith L. Black and Jean Paul Allain, have briefed congressional leaders during the Brain Mapping Days organized by BMF and SMBT. [24] [25]

Awards

Brain Mapping Foundation has partnered with Society for Brain Mapping and Therapeutics (SBMT) to identify the most important scientific and clinical contributions to the field, and recognize them with the prestigious “Pioneer” awards. The awards are presented in partnership with SBMT, industry leaders and other foundations to highlight the significant work done by scientists, industry leaders, individuals, and policymakers. [26] [27]

U.S. congresswoman Gabby Giffords is the only award recipient who has been recognized twice by the Society and the Foundation for her courage and dedication toward raising awareness for neurotrauma as well as her role in healthcare reform. She was awarded a Beacon of courage and dedication and Pioneer in healthcare policy award by the Foundation and the Society. [28] [29]

Global Physicians and Scientists (GPS)

GPS is a humanitarian program, which is focused on mobilizing physicians, scientists and surgeons to serve for few weeks in the poor and rural areas of the United States and abroad. This program collaborates with industry and government officials and uses the national and international SBMT centers as bases of operations. The program is designed to help alleviate healthcare disparities by bringing world class physicians to poor areas, and to help improve local economies through micro and neuro economics.

Related Research Articles

Functional neuroimaging

Functional neuroimaging is the use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. It is primarily used as a research tool in cognitive neuroscience, cognitive psychology, neuropsychology, and social neuroscience.

The first neuroimaging technique ever is the so-called 'human circulation balance' invented by Angelo Mosso in the 1880s and able to non-invasively measure the redistribution of blood during emotional and intellectual activity. Then, in the early 1900s, a technique called pneumoencephalography was set. This process involved draining the cerebrospinal fluid from around the brain and replacing it with air, altering the relative density of the brain and its surroundings, to cause it to show up better on an x-ray, and it was considered to be incredibly unsafe for patients. A form of magnetic resonance imaging (MRI) and computed tomography (CT) were developed in the 1970s and 1980s. The new MRI and CT technologies were considerably less harmful and are explained in greater detail below. Next came SPECT and PET scans, which allowed scientists to map brain function because, unlike MRI and CT, these scans could create more than just static images of the brain's structure. Learning from MRI, PET and SPECT scanning, scientists were able to develop functional MRI (fMRI) with abilities that opened the door to direct observation of cognitive activities.

Angular gyrus Gyrus of the parietal lobe of the brain

The angular gyrus is a region of the brain lying mainly in the posteroinferior region of the parietal lobe, occupying the posterior part of the inferior parietal lobule. It represents the Brodmann area 39.

Imaging genetics refers to the use of anatomical or physiological imaging technologies as phenotypic assays to evaluate genetic variation. Scientists that first used the term imaging genetics were interested in how genes influence psychopathology and used functional neuroimaging to investigate genes that are expressed in the brain.

Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the brain resulting in maps.

The Organization for Human Brain Mapping (OHBM) is an organization of scientists with the main aim of organizing an annual meeting.

Voxel-based morphometry Computational neuroanatomy method

Voxel-based morphometry is a computational approach to neuroanatomy that measures differences in local concentrations of brain tissue, through a voxel-wise comparison of multiple brain images.

<i>NeuroImage</i> Academic journal

NeuroImage is a peer-reviewed scientific journal covering research on neuroimaging, including functional neuroimaging and functional human brain mapping. The current Editor in Chief is Michael Breakspear. Abstracts from the annual meeting of the Organization for Human Brain Mapping have been published as supplements to the journal. Members of the Organization for Human Brain Mapping are eligible for reduced subscription rates. In 2012, Elsevier launched an online-only, open access sister journal to NeuroImage, entitled NeuroImage: Clinical.

Resting state fMRI Type of functional magnetic resonance imaging

Resting state fMRI is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed. A number of resting-state brain networks have been identified, one of which is the default mode network. These brain networks are observed through changes in blood flow in the brain which creates what is referred to as a blood-oxygen-level dependent (BOLD) signal that can be measured using fMRI.

The following outline is provided as an overview of and topical guide to brain mapping:

A brain atlas is composed of serial sections along different anatomical planes of the healthy or diseased developing or adult animal or human brain where each relevant brain structure is assigned a number of coordinates to define its outline or volume. Brain atlases are contiguous, comprehensive results of visual brain mapping and may include anatomical, genetic or functional features. A functional brain atlas is made up of regions of interest, where these regions are typically defined as spatially contiguous and functionally coherent patches of gray matter.

George Paxinos Greek Australian neuroscientist

George Paxinos AO DSc FASSA FAA FRSN FAHMS is a Greek Australian neuroscientist, born in Ithaca, Greece. He completed his BA in psychology at the University of California at Berkeley and his PhD at McGill University in Montreal, Canada. After a postdoctoral year at Yale University, he moved to the School of Psychology of the University of New South Wales in Sydney, Australia. He is currently an NHMRC Senior Principal Research Fellow at Neuroscience Research Australia and Scientia Professor of Medical Sciences at the University of New South Wales.

Nevzat Tarhan

Kaşif Nevzat Tarhan is a Turkish psychiatrist and Psychological warfare expert and neuropsychology expert.

The International Brain Mapping and Intraoperative Surgical Planning Society DBA The Society for Brain Mapping and Therapeutics (SBMT) is a non-profit biomedical association (501c6) principally concerned with Brain Mapping and Intra-operative Surgical planning. International Brain Mapping and Intraoperative Surgical planning Foundation (IBMISPF) DBA The Brain Mapping Foundation provides funding to members of the society.

The G20 World Brain Mapping & Therapeutic Scientific Summit aims to contribute to President Obama’s BRAIN initiative and to expand action on the current and upcoming initiatives across the G20 nations, bringing the finest scientists, engineers, physicians and surgeons across the globe in order to rapidly introduce clinical solutions for neurological disorders, which cost the world economy hundreds of billions of dollars annually. G20 World Brain Mapping Summit was launched in 2014 on the initiative of The Society for Brain Mapping and Therapeutics (SBMT).

Russell Poldrack

Russell "Russ" Alan Poldrack is an American psychologist and neuroscientist. He is a professor of Psychology at Stanford University, Associate Director of Stanford Data Science, member of the Stanford Neuroscience Institute and director of the Stanford Center for Reproducible Neuroscience and the SDS Center for Open and Reproducible Science.

Dynamic causal modeling (DCM) is a framework for specifying models, fitting them to data and comparing their evidence using Bayesian model comparison. It uses nonlinear state-space models in continuous time, specified using stochastic or ordinary differential equations. DCM was initially developed for testing hypotheses about neural dynamics. In this setting, differential equations describe the interaction of neural populations, which directly or indirectly give rise to functional neuroimaging data e.g., functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG) or electroencephalography (EEG). Parameters in these models quantify the directed influences or effective connectivity among neuronal populations, which are estimated from the data using Bayesian statistical methods.

NeuroVault

NeuroVault is an open-science neuroinformatics online repository of brain statistical maps atlases and parcellations.

References

  1. "Society for Brain Mapping and Therapeutics (SBMT) announce the formation of American Board of Brain Mapping, its 2013 award recipients and its Brain Mapping Day at the US Congress" (Press release). Society for Brain Mapping and Therapeutics. April 12, 2013. Archived from the original on March 28, 2014. Retrieved July 26, 2013.
  2. Fox, Jeffrey L (2013). "$350 million in new funding for brain research". Nature Biotechnology. 31 (6): 480. doi: 10.1038/nbt0613-480 . PMID   23752420.
  3. 1 2 Kateb, Babak; Chiu, Katherine; Black, Keith L.; Yamamoto, Vicky; Khalsa, Bhavraj; Ljubimova, Julia Y.; Ding, Hui; Patil, Rameshwar; et al. (2011). "Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: What should be the policy?". NeuroImage. 54 (Suppl 1): S106–24. doi:10.1016/j.neuroimage.2010.01.105. PMC   3524337 . PMID   20149882.
  4. "Neurosurgeon honoured by US congress - NSW Health". Archived from the original on 2013-07-22. Retrieved 2013-07-31.[ full citation needed ]
  5. "News - Charlie Teo addresses US Congress on brain cancer". Archived from the original on 2014-07-14. Retrieved 2014-07-14.
  6. http://newsroom.unsw.edu.au/news/health/mapping-human-brain%5B%5D%5B%5D
  7. Tzika, A. (2012). "Functional MRI using robotic MRI compatible devices for monitoring rehabilitation from chronic stroke in the molecular medicine era (Review)" (PDF). International Journal of Molecular Medicine. 29 (6): 963–73. doi:10.3892/ijmm.2012.942. PMC   3981645 . PMID   22426741.
  8. http://www.sciencedirect.com/science/journal/10538119/54/supp/S1%5B%5D
  9. http://www.sciencedirect.com/science/journal/10538119/47/supp/S2%5B%5D
  10. http://www.sciencedirect.com/science/journal/10538119/37/supp/S1%5B%5D
  11. http://blogs.plos.org/everyone/2012/06/27/plos-one-launches-the-neuromapping-therapeutics-collection/%5B%5D%5B%5D
  12. Babak Kateb, John D. Heiss. The Textbook of Nanoneuroscience and Nanoneurosurgery. CRC Press. 2013. 41 chapters. 602 pages. ISBN   9781439849415 [ page needed ]
  13. Kateb, Babak; Yamamoto, Vicky; Alizadeh, Darya; Zhang, Leying; Manohara, Harish M.; Bronikowski, Michael J.; Badie, Behnam (2010). "Multi-walled Carbon Nanotube (MWCNT) Synthesis, Preparation, Labeling, and Functionalization". Immunotherapy of Cancer. Methods in Molecular Biology. Vol. 651. pp. 307–17. doi:10.1007/978-1-60761-786-0_18. ISBN   978-1-60761-785-3. PMID   20686974.
  14. Kateb, Babak; Ryan, M.A.; Homer, M.L.; Lara, L.M.; Yin, Yufang; Higa, Kerin; Chen, Mike Y. (2009). "Sniffing out cancer using the JPL electronic nose: A pilot study of a novel approach to detection and differentiation of brain cancer". NeuroImage. 47: T5–9. doi:10.1016/j.neuroimage.2009.04.015. PMID   19362154.
  15. http://www.ndtv.com/article/sci-tech/nasa-s-e-nose-to-fight-brain-cancer-study-2762%5B%5D
  16. https://www.theregister.co.uk/2009/05/01/nasa_enose_cancer_sniffer%5B%5D%5B%5D
  17. "NASA's new e-nose can detect scent of cancerous brain cells".
  18. http://www.everydayhealth.com/sanjay-gupta/why-brain-mapping-matters.aspx%5B%5D%5B%5D
  19. https://www.sciencedaily.com/releases/2009/04/090430065456.htm%5B%5D%5B%5D
  20. http://www.networkworld.com/community/node/41467%5B%5D%5B%5D
  21. Kateb, Babak; Yamamoto, Vicky; Yu, Cheng; Grundfest, Warren; Gruen, John Peter (2009). "Infrared thermal imaging: A review of the literature and case report". NeuroImage. 47: T154–62. doi:10.1016/j.neuroimage.2009.03.043. PMID   19332140.
  22. http://www.elsevier.com/about/press-releases/health-sciences/elsevier-and-brain-mapping-foundation-co-host-6th-annual-world-congress-of-ibmisps-on-brain-mapping-and-image-guided-therapy%5B%5D%5B%5D
  23. http://worldbrainmapping.org/previous%5B%5D%5B%5D
  24. 1 2 "Cedars-Sinai".
  25. "Purdue takes research to Congress for Brain Mapping Day".
  26. "Top Scientists from US, Canada, and Australia, Member of the Canadian Parliament and Stryker Executive to be Honored by the Society of Brain Mapping and Therapeutics (SBMT)" (Press release). Society for Brain Mapping and Therapeutics. March 16, 2012.
  27. "Colonel honored with humanitarian award from the Brain Mapping Foundation for work with TBI".
  28. http://www.wafb.com/story/14313763/medical-group-to-honor-rep-giffords-with-award%5B%5D%5B%5D
  29. http://azjewishpost.com/2011/brain-mapping-society-to-honor-giffords/%5B%5D%5B%5D