Peripheral artery disease (PAD) is an abnormal narrowing of arteries other than those that supply the heart or brain. When narrowing occurs in the heart, it is called coronary artery disease, and in the brain, it is called cerebrovascular disease. Peripheral artery disease most commonly affects the legs, but other arteries may also be involved – such as those of the arms, neck, or kidneys. The classic symptom is leg pain when walking which resolves with rest, known as intermittent claudication. Other symptoms include skin ulcers, bluish skin, cold skin, or abnormal nail and hair growth in the affected leg. Complications may include an infection or tissue death which may require amputation; coronary artery disease, or stroke. Up to 50% of people with PAD do not have symptoms.
The endothelium is a single layer of squamous endothelial cells that line the interior surface of blood vessels, and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. Endothelial cells form the barrier between vessels and tissue and control the flow of substances and fluid into and out of a tissue.
The Heart Protection Study was a randomized controlled trial run by the Clinical Trial Service Unit, and funded by the Medical Research Council (MRC) and the British Heart Foundation (BHF) in the United Kingdom. It studied the use of the cholesterol lowering drug, simvastatin 40 mg and vitamin supplementation in people who were at risk of cardiovascular disease. It was led by Jane Armitage, an epidemiologist at the Clinical Trial Service Unit.
Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion, classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest. It is classically associated with early-stage peripheral artery disease, and can progress to critical limb ischemia unless treated or risk factors are modified.
Journal of Experimental Medicine is a monthly peer-reviewed medical journal published by Rockefeller University Press that publishes research papers and commentaries on the physiological, pathological, and molecular mechanisms that encompass the host response to disease. The journal prioritizes studies on intact organisms and has made a commitment to publishing studies on human subjects. Topics covered include immunology, inflammation, infectious disease, hematopoiesis, cancer, stem cells and vascular biology. The journal has no single editor-in-chief, but thirteen academic editors.
The British Journal of Surgery (BJS) is a monthly peer-reviewed publication targeting general surgeons and the associated subspecialities. At 6.939 it has the highest impact factor of any general surgical journal in Europe. It has been published since 1913 and is currently published by Oxford University Press.
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) is a peer-reviewed medical journal published on behalf of the American Heart Association by Lippincott Williams & Wilkins, an imprint of Wolters Kluwer. It covers basic and clinical research related to vascular biology, pathophysiology and complications of atherosclerosis, and thrombotic mechanisms in blood vessels.
Atherosclerosis is a monthly peer-reviewed scientific journal established in 1970 and published by Elsevier. It is the official journal of the European Atherosclerosis Society and is affiliated with the International Atherosclerosis Society.
Journal of the Renin-Angiotensin-Aldosterone System is a peer-reviewed academic journal that publishes papers in the field of Peripheral Vascular Disease. The journal's editors are Graham MacGregor and Peter Sever. It has been in publication since 2000 and is currently published by SAGE Publications.
Angiology is a peer-reviewed academic journal that publishes papers in the field of Vascular disease. The journal's editor is Dimitri P. Mikhailidis, M.D., FRCPATH. It has been in publication since 1950 and is currently published by SAGE Publications.
The Science of Diabetes Self-Management and Care is a peer-reviewed academic journal that publishes papers in the field of Endocrinology. The journal's editor is James Fain, PhD, RN, BC-ADM, FAAN. It has been in publication since 1980 and until 2021 was titled The Diabetes Educator. It is currently published by SAGE Publications in association with the Association of Diabetes Care & Education Specialists.
Diabetes and Vascular Disease Research is a peer-reviewed academic journal that publishes papers in the field of Peripheral vascular disease. The journal's editor is Peter Grant. It has been in publication since 2004 and is currently published by SAGE Publications.
Perfusion is a peer-reviewed academic journal that publishes papers in the field of cardiology. The journal's editor is Prakash P. Punjabi. It has been in publication since 1986 and is currently published by SAGE Publications.
Vascular Medicine is the premier ISI-ranked, peer-reviewed academic journal of vascular medicine comprising original research articles and reviews on vascular biology, epidemiology, diagnosis, medical treatment, and interventional therapy for vascular disease. The journal's editor is Dr. Heather L. Gornik, one of the top-ranking FMD specialists in the county. It has been in publication since 1990 and is currently published by Sage Publications on behalf of the Society for Vascular Medicine. This journal is a member of the Committee on Publication Ethics (COPE).
Cardiovascular Diabetology is a peer-reviewed open access medical journal covering the intersection of cardiology and diabetology, meaning the connection between diabetes, metabolic syndrome and cardiovascular diseases. It is published by BioMed Central and was established in 2002, with Enrique Fisman and Alexander Tenenbaum as founding editors-in-chief. Articles are published online upon acceptance, rather than in issues. A printed version is periodically distributed in India by Panacea Biotec Ltd.
The Caerphilly Heart Disease Study, also known as the Caerphilly Prospective Study (CaPS), is an epidemiological prospective cohort, set up in 1979 in a representative population sample drawn from Caerphilly, a typical small town in South Wales, UK.
Nikhil Tandon is an Indian endocrinologist, medical academic and the head of the department of endocrinology, metabolism and diabetes at the All India Institute of Medical Sciences. He is a recipient of Dr. B. C. Roy Award, the highest Indian medical award in 2005 and was honoured by the Government of India in 2015 with Padma Shri, the fourth highest Indian civilian award.
Robert B. Rutherford, MD, was an American vascular surgeon, scientific journal editor, and medical textbook author. He established the definitive textbook in vascular surgery and was a Senior Editor of the Journal of Vascular Surgery.
Arthur Scott Donkin was a British physician and writer known for his research on diabetes. Donkin proposed a skimmed milk treatment for Bright's disease and diabetes.
