 | A major contributor to this article appears to have a close connection with its subject.(July 2017) |
| Purpose | AIDS research |
|---|---|
| Location | |
Director | Salim Abdool Karim |
| Website | http://www.caprisa.org/ |
CAPRISA ("Centre for the AIDS Programme of Research in South Africa") is the name of an AIDS research center based in Durban, South Africa.
CAPRISA was established in 2002 under the National Institutes of Health program called Comprehensive International Program of Research on AIDS (CIPRA). Five partner institutions participated in the founding: University of KwaZulu-Natal, University of Cape Town, University of Western Cape, National Institute of Communicable Diseases, and Columbia University in New York. UNAIDS recognizes CAPRISA with the designation of "Collaborating Centre for HIV Prevention Research." [1]
CAPRISA's mission is to promote HIV prevention and research its epidemiology. [1]
CAPRISA 004 is the name of a clinical trial testing a microbicide which was experimentally shown to be effective in reducing women's risk of contracting HIV. [2]
The AIDS epidemic, caused by HIV, found its way to the United States between the 1970s and 1980s, but was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in homosexual men in Los Angeles, New York City, and San Francisco in 1981. Treatment of HIV/AIDS is primarily via the use of multiple antiretroviral drugs, and education programs to help people avoid infection.
HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). Some of its proponents reject the existence of HIV, while others accept that HIV exists but argue that it is a harmless passenger virus and not the cause of AIDS. Insofar as they acknowledge AIDS as a real disease, they attribute it to some combination of sexual behavior, recreational drugs, malnutrition, poor sanitation, haemophilia, or the effects of the medications used to treat HIV infection (antiretrovirals).
Microbicides for sexually transmitted infections are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause sexually transmitted infection.
The global epidemic of HIV/AIDS began in 1981, and is an ongoing worldwide public health issue. According to the World Health Organization (WHO), by 2023, HIV/AIDS had killed approximately 40.4 million people, and approximately 39 million people were infected with HIV globally. Of these 29.8 million people, 75% are receiving antiretroviral treatment. There were about 630,000 deaths from HIV/AIDS in 2022. The 2015 Global Burden of Disease Study estimated that the global incidence of HIV infection peaked in 1997 at 3.3 million per year. Global incidence fell rapidly from 1997 to 2005, to about 2.6 million per year. Incidence of HIV has continued to fall, decreasing by 23% from 2010 to 2020, with progress dominated by decreases in Eastern Africa and Southern Africa. As of 2020, there are approximately 1.5 million new infections of HIV per year globally.
FHI 360 is a nonprofit human development organization based in North Carolina. FHI 360 operates in more than 70 countries and all U.S. states and territories. Established in 1971, the organization manages projects relating to family planning and reproductive health. In 1986 the organization began a worldwide response to HIV/AIDS. FHI 360's research and programs also address malaria, tuberculosis, and other infectious and chronic diseases and international agencies, governments, foundations, research institutions, and individual donors.
HIV/AIDS is one of the most serious health concerns in South Africa. The country has the highest number of people afflicted with HIV of any country, and the fourth-highest adult HIV prevalence rate, according to the 2019 United Nations statistics.
The history of HIV/AIDS in Australia is distinctive, as Australian government bodies recognised and responded to the AIDS pandemic relatively swiftly, with the implementation of effective disease prevention and public health programs, such as needle and syringe programs (NSPs). As a result, despite significant numbers of at-risk group members contracting the virus in the early period following its discovery, Australia achieved and has maintained a low rate of HIV infection in comparison to the rest of the world.
The very high rate of human immunodeficiency virus infection experienced in Uganda during the 1980s and early 1990s created an urgent need for people to know their HIV status. The only option available to them was offered by the National Blood Transfusion Service, which carries out routine HIV tests on all the blood that is donated for transfusion purposes. The great need for testing and counseling resulted in a group of local non-governmental organizations such as The AIDS Support Organisation, Uganda Red Cross, Nsambya Home Care, the National Blood Bank, the Uganda Virus Research Institute together with the Ministry of Health establishing the AIDS Information Centre in 1990. This organization worked to provide HIV testing and counseling services with the knowledge and consent of the client involved.
The Desmond Tutu HIV Foundation (DTHF) is a nonprofit organization founded to provide treatment for and conduct HIV/AIDS research. It is based in Cape Town, South Africa, and is managed with the Desmond Tutu HIV Centre at the University of Cape Town. The Foundation operates community sites throughout greater Cape Town, providing treatment, testing, and outreach services to at-risk communities.
CAPRISA 004 is the name of a clinical trial conducted by CAPRISA. This particular study was the first to show that a topical gel could reduce a person's risk of contracting HIV. The gel used in the study contained a microbicide.
CONRAD is a non-profit organization scientific research organization that works to improve the reproductive health of women, especially in developing countries. CONRAD was established in 1986 under a cooperative agreement between Eastern Virginia Medical School (EVMS) and the United States Agency for International Development(USAID). CONRAD’s products are developed primarily for women in low-resource settings, in that they are designed to be safe, affordable and user-friendly. CONRAD is led by Scientific and Executive Director Gustavo Doncel, M.D., Ph.D. Primary funding for CONRAD comes from the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) through the U.S. Agency for International Development (USAID), with additional funding from The Bill & Melinda Gates Foundation and the National Institutes of Health (NIH).
mothers2mothers is an international nonprofit organization dedicated to preventing mother-to-child transmission of HIV by providing education and support for pregnant women and new mothers living with HIV.
Nicoli Nattrass is a South African development economist who is professor of economics at the University of Cape Town (UCT). She is the co-director of the Institute for Communities and Wildlife in Africa (iCWild) and was the founding director of the Centre for Social Science Research (CSSR).
Mervyn Wilfred Susser was a South African activist, doctor and epidemiologist.
Zena Athene Stein was a South African epidemiologist, activist and doctor. She was professor of epidemiology and psychiatry at Columbia University.
Quarraisha Abdool Karim is an infectious diseases epidemiologist and co-founder and Associate Scientific Director of CAPRISA. She is a Professor in Clinical Epidemiology, Columbia University, New York and Pro-Vice Chancellor for African Health, University of KwaZulu-Natal, South Africa.
Salim S. Abdool Karim, MBChB, MMed, MS(Epi), FFPHM, FFPath (Virol), DipData, PhD, DSc(hc), FRS is a South African public health physician, epidemiologist and virologist who has played a leading role in the AIDS and COVID-19 pandemic. His scientific contributions have impacted the landscape of HIV prevention and treatment, saving thousands of lives.
Wendee M. Wechsberg is an American social science researcher. Wechsberg's research focuses on developing and testing the efficacy of HIV prevention interventions among key populations of substance abusers globally. She is a recognized expert in the fields of substance abuse, gender inequality, and HIV. She developed the Women's CoOp intervention, a woman-focused behavioral HIV intervention that incorporates gender- and culture-specific skills training. Wechsberg is a Principal Researcher and Director of the Substance Use, Gender, and Applied Research (SUGAR) Program at RTI International and Director of the RTI Global Gender Center. She is also adjunct professor at the University of North Carolina at Chapel Hill (UNC) Gillings School of Global Public Health, Adjunct Professor of Psychology at North Carolina State University (NCSU), and adjunct professor in Psychiatry and Behavioral Sciences at Duke University School of Medicine.
Taghmeda Achmat, commonly known as Midi Achmat, is one of South Africa's most well known lesbian activists. Achmat co-founded the Treatment Action Campaign (TAC) with her partner and fellow activist Theresa Raizenberg on 10 December 1998.
Gita Ramjee was a Ugandan-South African scientist and researcher in HIV prevention. In 2018, she was awarded the ‘Outstanding Female Scientist’ award from the European and Developing Countries Clinical Trials Partnership. She died in Umhlanga, Durban, South Africa, from COVID-19 related complications.
