Laureates
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The Charles S. Mott Prize was awarded annually by the General Motors Cancer Research Foundation as one of a trio of scientific prizes entirely devoted to cancer research, the other two being the Charles F. Kettering Prize and the Alfred P. Sloan, Jr. Prize. The prizes, worth US$250,000, were awarded annually between 1979 and 2005. The awards were generally considered the most prestigious in the field. [1] [2]
The Mott Prize was awarded for "the most outstanding recent contribution related to the cause or prevention of cancer". In 2006, due to financial pressures on the corporation supporting the Foundation, the three awards were consolidated into a single $250,000 General Motors Cancer Research Award.[ who? ][ citation needed ]. In 2006, the first and only winner of the General Motors Cancer Research Award was Napoleone Ferrara. [3]
Since 2006 no further prizes have been awarded.
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The General Motors Company (GM) is an American multinational automotive manufacturing company headquartered in Detroit, Michigan, United States. It is the largest automaker in the United States and was the largest in the world for 77 years before losing the top spot to Toyota in 2008.
Roger & Me is a 1989 American documentary film written, produced, directed by, and starring Michael Moore, in his directorial debut. Moore portrays the regional economic impact of General Motors CEO Roger Smith's action of closing several auto plants in his hometown of Flint, Michigan, reducing GM's employees in that area from 80,000 in 1978 to about 50,000 in 1992. As of August 2015, GM employs approximately 7,200 workers in the Flint area, according to The Detroit News, and 5,000 workers according to MSNBC.
Charles Franklin Kettering sometimes known as Charles Fredrick Kettering was an American inventor, engineer, businessman, and the holder of 186 patents. He was a founder of Delco, and was head of research at General Motors from 1920 to 1947. Among his most widely used automotive developments were the electrical starting motor and leaded gasoline. In association with the DuPont Chemical Company, he was also responsible for the invention of Freon refrigerant for refrigeration and air conditioning systems. At DuPont he also was responsible for the development of Duco lacquers and enamels, the first practical colored paints for mass-produced automobiles. While working with the Dayton-Wright Company he developed the "Bug" aerial torpedo, considered the world's first aerial missile. He led the advancement of practical, lightweight two-stroke diesel engines, revolutionizing the locomotive and heavy equipment industries. In 1927, he founded the Kettering Foundation, a non-partisan research foundation, and was featured on the cover of Time magazine in January 1933.
Charles Stewart Mott was an American industrialist and businessman, a co-founder of General Motors, philanthropist, and the 50th and 55th mayor of Flint, Michigan.
Moses Judah Folkman was an American medical scientist best known for his research on tumor angiogenesis, the process by which a tumor attracts blood vessels to nourish itself and sustain its existence. He founded the field of angiogenesis research, which has led to the discovery of a number of therapies based on inhibiting or stimulating neovascularization.
Ian Hector Frazer is a Scottish-born Australian immunologist, the founding CEO and Director of Research of the Translational Research Institute (Australia). Frazer and Jian Zhou developed and patented the basic technology behind the HPV vaccine against cervical cancer at the University of Queensland. Researchers at the National Cancer Institute, Georgetown University, and University of Rochester also contributed to the further development of the cervical cancer vaccine in parallel.
The Charles F. Kettering Prize was a US$250,000 award given by the General Motors Cancer Research Foundation for the most outstanding recent contribution to the diagnosis or treatment of cancer.
The Flint Cultural Center (FCC) is a campus of cultural, scientific, and artistic institutes located in Flint, Michigan, United States. The institutions located on the grounds of the FCC are the Flint Institute of Arts, Flint Institute of Music, Sloan Museum, Flint Public Library, Buick Gallery & Research Center, Robert T. Longway Planetarium, The Whiting, and the Bower Theatre. The campus and some institutions are owned by Flint Cultural Center Corporation.
Paul Lawrence Modrich is an American biochemist, James B. Duke Professor of Biochemistry at Duke University and Investigator at the Howard Hughes Medical Institute. He is known for his research on DNA mismatch repair. Modrich received the Nobel Prize in Chemistry 2015, jointly with Aziz Sancar and Tomas Lindahl.
The Dr. Paul Janssen Award for Biomedical Research is given annually by Johnson & Johnson to honor the work of an active scientist in academia, industry or a scientific institute in the field of biomedical research. It was established in 2004 and perpetuates the memory of Paul Janssen, the founder of Janssen Pharmaceutica, a Johnson & Johnson subsidiary.
Harald zur Hausen NAS EASA APS is a German virologist and professor emeritus. He has done research on cervical cancer and discovered the role of papilloma viruses in cervical cancer, for which he received the Nobel Prize in Physiology or Medicine 2008.
Napoleone Ferrara, is an Italian-American molecular biologist who joined University of California, San Diego Moores Cancer Center in 2013 after a career in Northern California at the biotechnology giant Genentech, where he pioneered the development of new treatments for angiogenic diseases such as cancer, age-related macular degeneration (AMD), and diabetic retinopathy. At Genentech, he discovered VEGF—and made the first anti-VEGF antibody—which suppresses growth of a variety of tumors. These findings helped lead to development of the first clinically available angiogenesis inhibitor, bevacizumab (Avastin), which prevents the growth of new blood vessels into a solid tumor and which has become part of standard treatment for a variety of cancers. Ferrara's work led also to the development of ranibizumab (Lucentis), a drug that is highly effective at preventing vision loss in intraocular neovascular disorders.
Joseph F. Fraumeni Jr. is an American physician and cancer researcher. Born in Boston, he received an A.B. from Harvard College, an M.D. from Duke University, and an M.Sc. in epidemiology from the Harvard School of Public Health. He completed his medical residency at Johns Hopkins Hospital and Memorial Sloan-Kettering Cancer Center. He then joined the National Cancer Institute at the National Institutes of Health in 1962 as a commissioned officer of the U.S. Public Health Service, becoming the founding Director of the Division of Cancer Epidemiology and Genetics in 1995. He stepped down from this position in 2012 to become a senior investigator and advisor to the National Cancer Institute.
Charles L. Sawyers is a Howard Hughes Medical Institute (HHMI) investigator who holds the Marie-Josée and Henry R. Kravis Chair of the Human Oncology and Pathogenesis Program (HOPP) at Memorial Sloan Kettering Cancer Center (MSK). HOPP is a program created in 2006 that comprises researchers from many disciplines to bridge clinical and laboratory discoveries.
Mott is a surname and given name.
Arnold Jay Levine, is an American Molecular biologist. He was awarded the 1998 Louisa Gross Horwitz Prize for Biology or Biochemistry and was the first recipient of the Albany Medical Center Prize in Medicine and Biomedical Research in 2001 for his discovery of the tumor suppressor protein p53.
The Warren Alpert Foundation Prize is awarded annually to scientist(s) whose scientific achievements have led to the prevention, cure or treatment of human diseases or disorders, and/or whose research constitutes a seminal scientific finding that holds great promise of ultimately changing our understanding of or ability to treat disease. The prize was established in 1987 by the late philanthropist and businessman Warren Alpert and the Warren Alpert Foundation.
The Alfred P. Sloan Jr. Prize was a $250,000 award given by the General Motors Cancer Research Foundation for outstanding oncological research.
Anthony Rex Hunter is a British-American biologist who is a Professor of Biology at the Salk Institute for Biological Studies and the University of California San Diego. His research publications list his name as Tony Hunter.
Webster K. "Web" Cavenee is the Director of Strategic Alliances in Central Nervous System Cancers at the Ludwig Institute for Cancer Research and Distinguished Professor at the University of California, San Diego. He was the Director of the Ludwig Institute for Cancer Research until 2015 when it was taken over by Richard Kolodner. His laboratory studies gene mutations in cancer, most notably in EGFR and glioblastoma multiforme.
