Ayahuasca is a South American psychoactive beverage, traditionally used by Indigenous cultures and folk healers in the Amazon and Orinoco basins for spiritual ceremonies, divination, and healing a variety of psychosomatic complaints.
Terence Kemp McKenna was an American ethnobotanist and mystic who advocated for the responsible use of naturally occurring psychedelic plants. He spoke and wrote about a variety of subjects, including psychedelic drugs, plant-based entheogens, shamanism, metaphysics, alchemy, language, philosophy, culture, technology, ethnomycology, environmentalism, and the theoretical origins of human consciousness. He was called the "Timothy Leary of the '90s", "one of the leading authorities on the ontological foundations of shamanism", and the "intellectual voice of rave culture".
Entheogens are psychoactive substances, including psychedelic drugs, used in sacred contexts in religion for inducing spiritual development throughout history.
Harmala alkaloids are several alkaloids that act as monoamine oxidase inhibitors (MAOIs). These alkaloids are found in the seeds of Peganum harmala, as well as Banisteriopsis caapi (ayahuasca), leaves of tobacco and coffee beans. The alkaloids include harmine, harmaline, harmalol, and their derivatives, which have similar chemical structures, hence the name "harmala alkaloids". These alkaloids are of interest for their use in Amazonian shamanism, where they are derived from other plants. Harmine, once known as telepathine and banisterine, is a naturally occurring beta-carboline alkaloid that is structurally related to harmaline, and also found in the vine Banisteriopsis caapi. Tetrahydroharmine is also found in B. caapi and P. harmala. Dr. Alexander Shulgin has suggested that harmine may be a breakdown product of harmaline. Harmine and harmaline are reversible inhibitors of monoamine oxidase A (RIMAs). They can stimulate the central nervous system by inhibiting the metabolism of monoamine compounds such as serotonin and norepinephrine.
Dennis Jon McKenna is an American ethnopharmacologist, research pharmacognosist, lecturer and author. He is the brother of well-known psychedelics proponent Terence McKenna and is a founding board member and the director of ethnopharmacology at the Heffter Research Institute, a non-profit organization concerned with the investigation of the potential therapeutic uses of psychedelic medicines.
Jeremy Narby is a Canadian anthropologist and author.
Santo Daime is a universalistic/syncretic religion founded in the 1930s in the Brazilian Amazonian state of Acre based on the teachings of Raimundo Irineu Serra, known as Mestre Irineu. Santo Daime incorporates elements of several religious or spiritual traditions, mainly Folk Catholicism, Kardecist Spiritism, African animism and indigenous South American shamanism, including vegetalismo.
Jonathan Ott is an ethnobotanist, writer, translator, publisher, natural products chemist and botanical researcher in the area of entheogens and their cultural and historical uses, and helped coin the term "entheogen".
Icaro is a South American indigenous and mestizo colloquialism for magic song. Today, this term is commonly used to describe the medicine songs performed in vegetal ceremonies, especially by shamans in ayahuasca ceremonies.
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue.
Christian Rätsch was a German anthropologist and writer on topics like ethnopharmacology, psychoactive plants and animals.
Stephen T. Sinatra (15 October 1946 –19 June 2022) was a board-certified cardiologist specializing in integrative medicine. He was also a certified bioenergetic psychotherapist. He has published journal articles on cholesterol and coenzyme Q10. He has appeared on national radio and television broadcasts, including The Dr. Oz Show, The Doctors, CNN’s “Sunday Morning News,” XM Radio’s “America’s Doctor Dr. Mehmet Oz,” and PBS’s “Body & Soul." He was also the author of the monthly newsletter Heart, Health & Nutrition and founder of Heart MD Institute. Sinatra died on June 19, 2022.
Traditional Brazilian medicine includes many native South American elements, and imported African ones. It is predominantly used in areas where indigenous groups and African descendants reside, like in the northeast coast, nearly all interior regions including Amazon regions, savannahs, rainforest, foothills, and Pantanal. According to Romulo R. N. Alves, "although Brazil's health system is public...use of traditional remedies and rituals provide an economical way of healing for much of the populace, but that also does not mean that wealthy Brazilians don't seek it out as well. Traditional medicine is a deep part of Brazilian heritage."
Herbs are a widely distributed and widespread group of plants, excluding vegetables and other plants consumed for macronutrients, with savory or aromatic properties that are used for flavoring and garnishing food, for medicinal purposes, or for fragrances. Culinary use typically distinguishes herbs from spices. Herbs generally refers to the leafy green or flowering parts of a plant, while spices are usually dried and produced from other parts of the plant, including seeds, bark, roots and fruits.
Guillermo Arévalo Valera is a Shipibo vegetalista and businessperson from the Maynas Province of Peru. His Shipibo name is Kestenbetsa.
Researchers have noted the relationship between psychedelics and ecology, particularly in relation to the altered states of consciousness (ASC) produced by psychedelic drugs and the perception of interconnectedness expressed through ecological ideas and themes produced by the psychedelic experience. This is felt through the direct experience of the unity of nature and the environment of which the individual is no longer perceived as separate but intimately connected and embedded inside.
Zoe Helene is a cultural activist who founded Cosmic Sister, an environmental feminist collective, and coined the phrase “psychedelic feminism.”
Charles Grob is a professor of Psychiatry & Biobehavioral Sciences and Pediatrics and director of the Division of Child and Adolescent Psychiatry at Harbor–UCLA Medical Center. He received his two BS degrees from Oberlin College and Columbia University, before getting an MD from the State University of New York, Downstate Medical Center. Grob's research interests include anxiety and mood disorders and also self-medication and substance abuse. The FDA approved one of his Phase 1 studies to study the psychological and physiological effects of MDMA and the hallucinogen ayahuasca.
Jerome Sarris is Co-CEO of Psychae Therapeutics and Co-Director of the associated Not-For-Profit Psychae Institute. He was appointed Professor of Psychedelic Medicine at The Centre of Mental Health at Swinburne University of Technology He also holds Adjunct roles at NICM Health Research Institute at Western Sydney University, Australia, and at the Florey Institute of Neuroscience and Mental Health at the University of Melbourne, Australia.
The International Center for Ethnobotanical Education, Research, and Service (ICEERS) is a non-profit organization (NPO), headquartered in Barcelona. ICEERS is dedicated to transforming society's relationship with psychoactive plants by engaging with some of the fundamental issues resulting from the globalization of ayahuasca, iboga, and other ethnobotanicals. Founded in 2009, ICEERS is registered as a non-profit organization, and has charitable status in the Netherlands and Spain, and through partner organizations in the US and UK. ICEERS also has consultative status with the United Nations' ECOSOC.
