Christine Alewine

Last updated
Christine Alewine
Christine Alewine.jpg
Born
Christine K. Campo
Alma mater Dartmouth College (BA)
University of Maryland School of Medicine (MD, PhD)
Children2
Scientific career
FieldsOncology, biology
Institutions National Cancer Institute
Thesis PDZ protein regulation of Kir 2.3  (2006)

Christine Campo Alewine is an American oncologist and biologist researching immunotoxin therapeutics in pancreatic cancer. [1] She is an investigator at the National Cancer Institute. [2]

Contents

Education

Campo completed a B.A. in chemistry and Asian studies at Dartmouth College. In college, she interned under chemist Karen Wetterhahn focusing on the environmental effects of toxic metals. It was in this lab that Alewine was introduced to MD–PhD programs and became interested in becoming a physician-scientist. She completed a postbaccalaureate program at the National Cancer Institute's laboratory of pathology from 1998 to 1999. [3] Campo earned a M.D. and Ph.D. from the University of Maryland School of Medicine. [4] Her dissertation in 2006 was titled, PDZ protein regulation of Kir 2.3. [5] She completed internal medicine residency in the Osler Medical Training Program at Johns Hopkins Hospital followed by clinical fellowship in medical oncology at NCI. [4]

Career and research

She joined NCI's laboratory of molecular biology as an assistant clinical investigator through the support of the clinical investigator development program in 2014 and became a tenure-track investigator through the NIH Lasker Scholar program in 2016. [4] Alewine researches the use of immunotoxin therapeutics in pancreatic cancer. [6] Her lab and clinic are testing and refining two recombinant immunotoxins that target a protein called mesothelin that is present on the surface of several types of cancer tumor cells, including pancreatic, ovarian, and some lung cancers. [7]

Personal life

Alewine is married and has two daughters. [3]

Related Research Articles

An anti-CD22 immunotoxin is a monoclonal antibody linked to a cytotoxic agent. They are being studied in the treatment of some types of B-cell cancer.

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References

  1. "2016 Social Media Events - The Future of Pancreatic Cancer Research and Treatment - NCI". www.cancer.gov. 2017-03-28. Retrieved 2024-07-16.
  2. "NCI Explores AI to Screen For and Treat Pancreatic Cancer". GovCIO Media & Research. 2023-10-30. Retrieved 2024-07-16.
  3. 1 2 "Lasker Clinical Research Scholars". NIH Intramural Research Program. 2017-02-27. Retrieved 2020-07-21.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  4. 1 2 3 "Principal Investigators". NIH Intramural Research Program. Retrieved 2020-07-21.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  5. Campo, Christine K. (2006). PDZ protein regulation of Kir 2.3 (PhD thesis). University of Maryland, Baltimore. OCLC   77637455.
  6. "Christine Campo Alewine, M.D., Ph.D." Center for Cancer Research. 2014-08-12. Retrieved 2020-07-21.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  7. "Dr. Christine Alewine — Treating Pancreatic Cancer with New Immunotoxin Strategies". NIH Intramural Research Program. 2019-02-04. Retrieved 2020-07-21.PD-icon.svg This article incorporates text from this source, which is in the public domain .