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A pandemic is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide.
An influenza pandemic is an epidemic of an influenza virus that spreads across a large region and infects a large proportion of the population. There have been six major influenza epidemics in the last 140 years, with the 1918 flu pandemic being the most severe; this is estimated to have been responsible for the deaths of 50–100 million people. The 2009 swine flu pandemic resulted in under 300,000 deaths and is considered relatively mild. These pandemics occur irregularly.
The Johns Hopkins Center for Health Security is an independent, nonprofit organization of the Johns Hopkins Bloomberg School of Public Health. The center works to protect people's health from epidemics and pandemics and ensures that communities are resilient to major challenges. The center is also concerned with biological weapons and the biosecurity implications of emerging biotechnology.
Margaret Ann "Peggy" Hamburg is an American physician and public health administrator, who is serving as the chair of the board of the American Association for the Advancement of Science (AAAS) and co-chair of the InterAcademy Partnership (IAP). She served as the 21st Commissioner of the U.S. Food and Drug Administration from May 2009 to April 2015.
Atlantic Storm was a ministerial exercise simulating the top-level response to a bioterror incident. The simulation operated on January 14, 2005, in Washington, D.C. It was created in part to reveal the current international state of preparedness and possible political and public health issues that might evolve from such a crisis.
A H5N1 vaccine is an influenza vaccine intended to provide immunization to influenza A virus subtype H5N1.
Disease X is a placeholder name that was adopted by the World Health Organization (WHO) in February 2024 on their shortlist of blueprint priority diseases to represent a hypothetical, unknown pathogen that could cause a future epidemic. The WHO adopted the placeholder name to ensure that their planning was sufficiently flexible to adapt to an unknown pathogen. Director of the US National Institute of Allergy and Infectious Diseases Anthony Fauci stated that the concept of Disease X would encourage WHO projects to focus their research efforts on entire classes of viruses, instead of just individual strains, thus improving WHO capability to respond to unforeseen strains. In 2020, experts, including some of the WHO's own expert advisors, speculated that COVID-19, caused by the SARS-CoV-2 virus strain, met the requirements to be the first Disease X.
The COVID-19 pandemic, also known as the coronavirus pandemic, is a global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified in an outbreak in the Chinese city of Wuhan in December 2019, and spread to other areas of Asia and then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020. The WHO ended its PHEIC declaration on 5 May 2023. As of 22 February 2024, the pandemic has caused 774,493,392 cases and 7,026,534 confirmed deaths, ranking it fifth in the list of the deadliest epidemics and pandemics in history.
Jennifer Nuzzo is an American epidemiologist. She is Director of the Pandemic Center and Professor of Epidemiology at the Brown University School of Public Health, having previously taught at the Johns Hopkins Bloomberg School of Public Health. She is also a Senior Fellow for Global Health at the Council on Foreign Relations.
Syra Madad is an American pathogen preparedness expert and infectious disease epidemiologist. Madad is the Senior Director of the System-wide Special Pathogens Program at NYC Health + Hospitals where she is part of the executive leadership team which oversees New York City's response to the Coronavirus disease 2019 pandemic in the city's 11 public hospitals. She was featured in the Netflix documentary series Pandemic: How to Prevent an Outbreak and the Discovery Channel documentary The Vaccine: Conquering COVID.
Crimson Contagion was a joint exercise conducted from January to August 2019, in which numerous national, state and local, private and public organizations in the US participated, in order to test the capacity of the federal government and twelve states to respond to a severe pandemic of influenza originating in China.
Pandemic prevention is the organization and management of preventive measures against pandemics. Those include measures to reduce causes of new infectious diseases and measures to prevent outbreaks and epidemics from becoming pandemics.
Exercise Cygnus was a three-day simulation exercise carried out by the UK Government in October 2016 to estimate the impact of a hypothetical H2N2 influenza pandemic on the United Kingdom. It aimed to identify strengths and weaknesses within the United Kingdom health system and emergency response chain by putting it under significant strain, providing insight on the country's resilience and any future ameliorations required. It was conducted by Public Health England representing the Department of Health and Social Care, as part of a project led by the "Emergency Preparedness, Resilience and Response Partnership Group". Twelve government departments across Scotland, Wales and Northern Ireland, as well as local resilience forums (LRFs) participated. More than 950 workers from those organisations, prisons and local or central government were involved during the three-day simulation, and their ability to cope under situations of high medical stress was tested.
Planning and preparing for pandemics has happened in countries and international organizations. The World Health Organization writes recommendations and guidelines, though there is no sustained mechanism to review countries' preparedness for epidemics and their rapid response abilities. National action depends on national governments. In 2005–2006, before the 2009 swine flu pandemic and during the decade following it, the governments in the United States, France, UK, and others managed strategic health equipment stocks, but they often reduced stocks after the 2009 pandemic in order to reduce costs.
Peter Daszak is a British zoologist, consultant and public expert on disease ecology, in particular on zoonosis. He is the president of EcoHealth Alliance, a nonprofit non-governmental organization that supports various programs on global health and pandemic prevention. He is also a member of the Center for Infection and Immunity at the Columbia University Mailman School of Public Health. He lives in Suffern, New York.
Crystal Watson is a senior scholar at the Johns Hopkins Center for Health Security and an associate professor in the Department of Environmental Health and Engineering. She is an expert in health security, biodefense, and risk assessment and preparedness for emerging infectious diseases. She is currently working on the public health response to the COVID-19 pandemic.
Part of managing an infectious disease outbreak is trying to delay and decrease the epidemic peak, known as flattening the epidemic curve. This decreases the risk of health services being overwhelmed and provides more time for vaccines and treatments to be developed. Non-pharmaceutical interventions that may manage the outbreak include personal preventive measures such as hand hygiene, wearing face masks, and self-quarantine; community measures aimed at physical distancing such as closing schools and cancelling mass gathering events; community engagement to encourage acceptance and participation in such interventions; as well as environmental measures such surface cleaning. It has also been suggested that improving ventilation and managing exposure duration can reduce transmission.
Saskia Popescu is an infectious disease epidemiologist and global health security expert in Phoenix, Arizona. She is an Assistant Professor of epidemiology at the University of Maryland, and holds academic appointments at the University of Arizona and George Mason University’s Schar School of Policy and Government, where she lectures on biopreparedness and outbreak response. Since the start of the Coronavirus disease 2019 pandemic, Popescu has worked to prepare for and mitigate the spread of the disease within healthcare and the entertainment industry, where she led the global epidemiology and infection prevention response for Netflix. She has been recognized for her communication efforts around the pandemic, as well as her work on the front lines in infection prevention and healthcare biopreparedness. Popescu currently is a Senior Fellow at the Council on Strategic Risks, addressing converging biological risks from biological weapons nonproliferation, biosecurity, emerging infectious diseases and ecological security, biopreparedness in private industry, and global health security vulnerabilities.
Amesh Adalja is an American infectious disease physician. He specializes in infectious disease, bioterrorism, and emergency medicine at Johns Hopkins Center for Health Security and a clinical assistant professor at the University of Pittsburgh School of Medicine.
References
- ↑ Watson, Crystal; Toner, Eric S.; Shearer, Matthew P.; Rivers, Caitlin; Meyer, Diane; Hurtado, Christopher; Watson, Matthew; Gronvall, Gigi Kwik; Adalja, Amesh A.; Sell, Tara Kirk; Inglesby, Tom; Cicero, Anita (2019-10-07). "Clade X: A Pandemic Exercise". Health Security. 17 (5): 410–417. doi:10.1089/hs.2019.0097. ISSN 2326-5094.
- ↑ Loria, Kevin. "This Pandemic Could Kill 900 Million People if It Happened Today, Warns Leading Medical Institute". ScienceAlert. Retrieved 2018-07-30.
- ↑ Seidel, Jamie (2018-07-30). "A virus attack could end the world". news.com.au. Retrieved 2018-07-31.
- ↑ Waugh, Rob (2018-07-30). "Pandemic 'could wipe out 900 million people,' experts warn". Metro. Retrieved 2018-07-30.
- ↑ Johns Hopkins Center for Health Security (2021-12-16). "About Clade X, a tabletop exercise". Johns Hopkins Center for Health Security. Retrieved 2022-02-06.
- ↑ "Clade X: A Global Health Security Pandemic Simulation Highlights Need to Support Global Health Security Initiatives". Global Health Council . 2018-08-16. Archived from the original on 2022-03-29. Retrieved 2024-02-22.
- ↑ Mandal, Ananya (2018-07-31). "World not ready to deal with a viral pandemic". News-Medical. Archived from the original on 2021-04-04. Retrieved 2024-02-22.
