Near-infrared spectroscopy (NIRS) is a spectroscopic method that uses the near-infrared region of the electromagnetic spectrum. Typical applications include medical and physiological diagnostics and research including blood sugar, pulse oximetry, functional neuroimaging, sports medicine, elite sports training, ergonomics, rehabilitation, neonatal research, brain computer interface, urology, and neurology. There are also applications in other areas as well such as pharmaceutical, food and agrochemical quality control, atmospheric chemistry, combustion research and knowledge.
Functional near-infrared spectroscopy (fNIRS) is an optical brain monitoring technique which uses near-infrared spectroscopy for the purpose of functional neuroimaging. Using fNIRS, brain activity is measured by using near-infrared light to estimate cortical hemodynamic activity which occur in response to neural activity. Alongside EEG, fNIRS is one of the most common non-invasive neuroimaging techniques which can be used in portable contexts. The signal is often compared with the BOLD signal measured by fMRI and is capable of measuring changes both in oxy- and deoxyhemoglobin concentration, but can only measure from regions near the cortical surface. fNIRS may also be referred to as Optical Topography (OT) and is sometimes referred to simply as NIRS.
Britton "Brit" Chance was an American biochemist, biophysicist, scholar, and inventor whose work helped develop spectroscopy as a way to diagnose medical problems. He was "a world leader in transforming theoretical science into useful biomedical and clinical applications" and is considered "the founder of the biomedical photonics." He received the National Medal of Science in 1974.
Bruce J. Tromberg is an American photochemist and a leading researcher in the field of biophotonics. He is the director of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) within the National Institutes of Health (NIH). Before joining NIH, he was Professor of Biomedical Engineering at The Henry Samueli School of Engineering and of Surgery at the School of Medicine, University of California, Irvine. He was the principal investigator of the Laser Microbeam and Medical Program (LAMMP), and the Director of the Beckman Laser Institute and Medical Clinic at Irvine. He was a co-leader of the Onco-imaging and Biotechnology Program of the NCI Chao Family Comprehensive Cancer Center at Irvine.
Laura-Ann Petitto is a cognitive neuroscientist and a developmental cognitive neuroscientist known for her research and scientific discoveries involving the language capacity of chimpanzees, the biological bases of language in humans, especially early language acquisition, early reading, and bilingualism, bilingual reading, and the bilingual brain. Significant scientific discoveries include the existence of linguistic babbling on the hands of deaf babies and the equivalent neural processing of signed and spoken languages in the human brain. She is recognized for her contributions to the creation of the new scientific discipline, called educational neuroscience. Petitto chaired a new undergraduate department at Dartmouth College, called "Educational Neuroscience and Human Development" (2002-2007), and was a Co-Principal Investigator in the National Science Foundation and Dartmouth's Science of Learning Center, called the "Center for Cognitive and Educational Neuroscience" (2004-2007). At Gallaudet University (2011–present), Petitto led a team in the creation of the first PhD in Educational Neuroscience program in the United States. Petitto is the Co-Principal Investigator as well as Science Director of the National Science Foundation and Gallaudet University’s Science of Learning Center, called the "Visual Language and Visual Learning Center (VL2)". Petitto is also founder and Scientific Director of the Brain and Language Laboratory for Neuroimaging (“BL2”) at Gallaudet University.
Oxygen saturation is the fraction of oxygen-saturated haemoglobin relative to total haemoglobin in the blood. The human body requires and regulates a very precise and specific balance of oxygen in the blood. Normal arterial blood oxygen saturation levels in humans are 96–100 percent. If the level is below 90 percent, it is considered low and called hypoxemia. Arterial blood oxygen levels below 80 percent may compromise organ function, such as the brain and heart, and should be promptly addressed. Continued low oxygen levels may lead to respiratory or cardiac arrest. Oxygen therapy may be used to assist in raising blood oxygen levels. Oxygenation occurs when oxygen molecules enter the tissues of the body. For example, blood is oxygenated in the lungs, where oxygen molecules travel from the air and into the blood. Oxygenation is commonly used to refer to medical oxygen saturation.
The International Society on Oxygen Transport to Tissue (ISOTT) is an interdisciplinary society of approximately 300 members that represents essentially every major tissue oxygen research laboratory in the world. Its purpose is to further the understanding of all aspects of the processes involved in the oxygen transport from the air to its ultimate consumption in the cells of the various organs of the body.
Duane Frederick Bruley is an American researcher, entrepreneur, and academician.
Melvin Henry Knisely was an American physiologist who first observed the pathological clumping of red and white cells, in vivo, at the capillary level. One of the most cited Knisely works was his research which documented the fact that even one alcoholic drink kills brain cells, which are irreplaceable.
David Thomas Delpy,, is a British bioengineer, and Hamamatsu Professor of Medical Photonics, at University College London.
Herman Stanton Bachelard was a British neurochemist, editor-in-chief and neuroscience book writer. He was born in Melbourne, Australia, and gained his BSc in Chemistry and Microbiology from Melbourne University in 1951, achieving an MSc and PhD in Biochemistry at Monash University. He developed most of his academic career in the United Kingdom, where Professor Bachelard headed the Departments of Biochemistry of the University of Bath and St Thomas' Hospital King's College London School of Medicine, concluding his career as Emeritus Professor of Physics at the University of Nottingham.
Edward Osmund Royle Reynolds, CBE, FRCP, FRCOG, FRCPCH, FMedSci, FRS, was a British paediatrician and Neonatologist who was most notable for the introduction of new techniques intended to improve the survival of newborns, especially those with respiratory failure, and for a series of papers regarding the value of techniques such as ultrasound imaging, nuclear magnetic resonance spectroscopy, and near infrared spectroscopy in determining the development and response to injury of the infant brain after birth.
Elizabeth M. C. Hillman is a British-born academic who is Professor of Biomedical Engineering and Radiology at Columbia University. She was awarded the 2011 Adolph Lomb Medal from The Optical Society and the 2018 SPIE Biophotonics Technology Innovator Award.
Anita Mahadevan-Jansen is a Professor of Biomedical Engineering and holds the Orrin H. Ingram Chair in Biomedical Engineering at Vanderbilt University. Her research considers the development of optical techniques for clinical diagnosis and surgical guidance, particularly using Raman and fluorescence spectroscopy. She serves on the Board of Directors of SPIE, and is a Fellow of SPIE, The Optical Society, Society for Applied Spectroscopy, and the American Society for Lasers in Medicine and Surgery. She was elected to serve as the 2020 Vice President of SPIE. With her election, Mahadevan-Jansen joined the SPIE presidential chain and served as President-Elect in 2021 and the Society's President in 2022.
Rebeccah Slater is a British neuroscientist and academic. She is professor of paediatric neuroscience and a senior Wellcome Trust research fellow at the University of Oxford. She is also a professorial fellow in Neuroscience at St John's College.
Melinda Jane Duer is Professor of Biological and Biomedical Chemistry in the Department of Chemistry at the University of Cambridge, and was the first woman to be appointed to an academic position in the department. Her research investigates changes in molecular structure of the extracellular matrix in tissues in disease and during ageing. She serves as Deputy Warden of Robinson College, Cambridge. She is an editorial board member of the Journal of Magnetic Resonance.
Markita del Carpio Landry is a Bolivian-American chemist who is an associate professor in the department of chemical engineering at the University of California, Berkeley. Her research considers nanomaterials for brain imaging and the development of sustainable crops. She was a recipient of the 2022 Vilcek prize for creative promise. del Carpio Landry's work has been featured on NPR, popular mechanics, the San Francisco Chronicle, and C&E News.
Igor Meglinski is a British, New Zealand and Finnish scientist serving as a principal investigator at the College of Engineering & Physical Sciences at Aston University, where he is a Professor in Quantum Biophotonics and Biomedical Engineering. He is a Faculty member in the School of Engineering and Technology at the Department of Mechanical, Biomedical & Design Engineering, and is also associated with the Aston Institute of Photonic Technologies (AIPT) and Aston Research Centre for Health in Ageing (ARCHA).
Digistain is a Harvard backed medical technology, registered and cleared with the UK’s Medicines and Health Regulatory Agency that provides oncologists with decision support data to guide therapy decisions in cancer patients. Cost effectively with an accelerated turnaround time of under an hour. Comparable diagnostics delay treatment decisions by several weeks and are cost prohibitive, limiting their clinical value especially in the community setting due to accessibility. Initial validation of Digistain has been achieved with early stage hormone positive breast cancer. The technology is used widely by oncologists to support the decision to administer or not to administer chemotherapy in early stage patients. Digistain’s technology can accurately predict breast cancer patients who are at at low risk of disease recurrence and forgo adjuvant chemotherapy.
Judit Gervain is a psychologist, neurolinguist and acquisitionist who is professor of developmental psychology at the University of Padua.
