Company type | Private |
---|---|
Industry | Clinical and applied markets |
Founded | 2014 |
Founders | Sasan Amini, Mahni Ghorashi |
Headquarters | , |
Area served | Global |
Key people | Sasan Amini, CEO and Co-founder; Ramin Khaksar, CSO, COO, and Co-founder |
Products | Fully automated genomics testing |
Number of employees | 50+ |
Website | www |
Clear Labs, Inc. is a private genomics testing company headquartered in San Carlos, California, United States. It offers a fully automated, next-generation sequencing (NGS) platform for turnkey diagnostics, including SARS-CoV-2 genomic characterization and detection of foodborne pathogens such as listeria and salmonella. [1] It can also verify a food's ingredients, its GMO status, or conduct other tests. [2]
Clear Labs was co-founded by Sasan Amini and Mahni Ghorashi in 2014, [3] who left their jobs at a genomics company to start Clear Labs. [4] The company acquired $6.5 million in series A financing in September 2015. [3] In December 2016, the company closed a $16 million Series B funding round. [5] This was followed by another $21 million round in October 2018. [6]
Clear Labs was granted an Emergency Use Authorization (EUA) from the US FDA in September 2020 for its SARS-CoV-2 descriptive diagnostic test. [7] Clear Labs launched in January 2021 a groundbreaking solution for whole genome sequencing surveillance of SARS-CoV-2 and its mutations. [8] Clear Labs announced in March 2021 that the company had reached a critical milestone of over 50% public health laboratory penetration with its whole genome sequencing SARS-CoV-2 product, [9] [10] including laboratories such as Nebraska, [11] [12] [13] Nevada, [14] [15] New York, [16] California [17] and Kansas, [18] among others. Clear Labs Raised a $60M Series C round led by Morgan Stanley and T. Rowe Price in May 2021. [19]
Clear Labs has also received governmental and professional certification for its food safety next generation sequencing platform, including from the International AOAC [20] in December 2019 and the National Poultry Improvement Plan in October 2021. [21]
bioMérieux SA is a French multinational biotechnology company founded and headquartered in Marcy-l'Étoile, France, close to Lyon. bioMérieux is present in 44 countries and serves more than 160 countries through a large network of distributors.
CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB) is a scientific research institute devoted primarily to biological research. It is a part of Council of Scientific and Industrial Research (CSIR), India.
The National Centre for Disease Control is an institute under the Indian Directorate General of Health Services, Ministry of Health and Family Welfare. It was established in July 1963 for research in epidemiology and control of communicable diseases and to reorganize the activities of the Malaria Institute of India. It has nine branches at Alwar, Bengaluru, Trivandrum, Calicut, Coonoor, Jagdalpur, Patna, Rajahmundry and Varanasi to advise the respective state governments on public health. The headquarters are in Sham Nath Marg, in New Delhi.
Dr Vinod Scaria FRSB, FRSPH is an Indian biologist, medical researcher pioneering in Precision Medicine and Clinical Genomics in India. He is best known for sequencing the first Indian genome. He was also instrumental in the sequencing of The first Sri Lankan Genome, analysis of the first Malaysian Genome sequencing and analysis of the Wild-type strain of Zebrafish and the IndiGen programme on Genomics for Public Health in India.
Molecular diagnostics is a collection of techniques used to analyze biological markers in the genome and proteome, and how their cells express their genes as proteins, applying molecular biology to medical testing. In medicine the technique is used to diagnose and monitor disease, detect risk, and decide which therapies will work best for individual patients, and in agricultural biosecurity similarly to monitor crop- and livestock disease, estimate risk, and decide what quarantine measures must be taken.
DiaSorin S.p.A. is an Italian multinational biotechnology company that produces and markets in vitro diagnostics reagent kits used in immunodiagnostics and molecular diagnostics and since July 2021, it is also active in the Life Science business. The group was founded in 2000 and is headquartered in Saluggia, Italy. Its production is at several plants located in Europe and the United States: Saluggia and Gerenzano (Italy), Dietzenbach (Germany), Stillwater, Minnesota (US), Dartford (UK). Following the acquisition of Luminex, the company acquired five additional production plants located in the United States and in Canada (Toronto). The company is a constituent of the FTSE MIB index.
Color Health, Inc. makes population-scale cancer detection and care accessible, convenient, and cost-effective for employers, health plans, and unions. With nearly a decade of experience, Color has served millions of patients and partnered with innovators such as the National Institutes of Health, the CDC, large public health departments, and more.
The Philippine Genome Center (PGC) is a multi-disciplinary research facility in Quezon City, Metro Manila, Philippines which specializes in genomics.
Mahni Ghorashi is a Silicon Valley entrepreneur, CMO and most recently served as Chief Strategy Officer for the state of Tennessee's economic development program for startups and venture capital.
Cluster 5 is a designation used by the Danish Statens Serum Institut for a virus variant described by the institute in autumn 2020, in connection with investigations of SARS-CoV-2 infection among mink and humans in the north of Jutland, Denmark.
Bamlanivimab is a monoclonal antibody developed by AbCellera Biologics and Eli Lilly as a treatment for COVID-19. The medication was granted an emergency use authorization (EUA) by the US Food and Drug Administration (FDA) in November 2020, and the EUA was revoked in April 2021.
The Alpha variant (B.1.1.7) was a SARS-CoV-2 variant of concern. It was estimated to be 40–80% more transmissible than the wild-type SARS-CoV-2. Scientists more widely took note of this variant in early December 2020, when a phylogenetic tree showing viral sequences from Kent, United Kingdom looked unusual.
The Beta variant, (B.1.351), was a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants initially believed to be of particular importance, it was first detected in the Nelson Mandela Bay metropolitan area of the Eastern Cape province of South Africa in October 2020, which was reported by the country's health department on 18 December 2020. Phylogeographic analysis suggests this variant emerged in the Nelson Mandela Bay area in July or August 2020.
The COVID-19 Genomics UK (COG-UK) consortium was a group of academic institutions and public health agencies in the United Kingdom created in April 2020 to collect, sequence and analyse genomes of SARS-CoV-2 at scale, as part of COVID-19 pandemic response.
Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are of enough significance to lead virologists to label them separately. SARS-CoV-2 is the virus that causes coronavirus disease 2019 (COVID-19). Some have been stated, to be of particular importance due to their potential for increased transmissibility, increased virulence, or reduced effectiveness of vaccines against them. These variants contribute to the continuation of the COVID-19 pandemic.
The Gamma variant (P.1) was one of the variants of SARS-CoV-2, the virus that causes COVID-19. This variant of SARS-CoV-2 has been named lineage P.1 and has 17 amino acid substitutions, ten of which in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. It was first detected by the National Institute of Infectious Diseases (NIID) of Japan, on 6 January 2021 in four people who had arrived in Tokyo having visited Amazonas, Brazil, four days earlier. It was subsequently declared to be in circulation in Brazil. Under the simplified naming scheme proposed by the World Health Organization, P.1 was labeled Gamma variant, and was considered a variant of concern until March 2022, when it was largely displaced by the delta and omicron variants.
INSACOG is the forum set up under the Ministry of Health and Family Welfare by the Government of India on 30 December 2020, to study and monitor genome sequencing and virus variation of circulating strains of COVID-19 in India. Initially it was tasked to study the virus variant Lineage B.1.1.7 earlier found in United Kingdom in December 2020.
COVID-19 rapid antigen tests or RATs, also frequently called COVID-19 lateral flow tests or LFTs, are rapid antigen tests used to detect SARS-CoV-2 infection (COVID-19). They are quick to implement with minimal training, cost a fraction of other forms of COVID-19 testing, and give users a result within 5–30 minutes. RATs have been used in several countries as part of mass testing or population-wide screening approaches. Many RATs can be used for self-testing, in which an individual "collects their own specimen… and interpret[s] their test result themselves".
The African Centre of Excellence for Genomics of Infectious Diseases (ACEGID), based at Redeemer’s University, Ede, Nigeria, is a consortium of West African academic and medical institutions partnering for research and training.
Alexander L. Greninger is assistant director of the UW Medicine Clinical Virology Laboratory, director of the Retrovirology/Clinical Trials Laboratory, and the Larry Corey Endowed professor of Laboratory Medicine. His research is focused on genomic and proteomic characterization of a variety of human viruses and bacteria, with a focus on respiratory viruses and human herpesviruses.