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Acne, also known as acne vulgaris, is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and possible scarring. It primarily affects skin with a relatively high number of oil glands, including the face, upper part of the chest, and back. The resulting appearance can lead to anxiety, reduced self-esteem, and, in extreme cases, depression or thoughts of suicide.
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name accutane among others, is a medication primarily used to treat severe acne. It is also used to prevent certain skin cancers, and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.
Tretinoin, also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia. For acne, it is applied to the skin as a cream, gel or ointment. For leukemia, it is taken by mouth for up to three months.
Warner Chilcott was a company in the pharmaceutical industry based in Rockaway, New Jersey. It was primarily focused on women’s healthcare and dermatology. On October 1, 2013, the company was acquired by Actavis.
Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin.
Dilip Shanghvi is an Indian billionaire businessman and one of the country's richest people. He founded Sun Pharmaceuticals. The Government of India awarded him the civilian honour of the Padma Shri in 2016. India Today magazine ranked him 8th in India's most powerful people of 2017 list.
Nicomide is an acne medication available in topical cream, topical gel and vitamin supplement form. Tablets available by prescription only and contain the active ingredients nicotinamide, zinc, copper, and folic acid. The topical cream and topical gel are formulated into a 4% nicotinamide mixture. Dermatologists say this medication reduces inflammation of the skin, thereby reducing acne. Results from a well-controlled clinical trial in Caucasian and Japanese women have shown that 4-6 weeks of application of 2 percent nicotinamide moisturiser to the face decreases sebum production with significant differences in facial shine and oiliness.Nicotinamide gel is marketed as an over-the-counter treatment for acne in Canada, Australia, NZ, UK, USA and Ireland. If a twice-daily application causes excessive drying of the skin, one may reduce to once a day, or every other day.Nicotinamide gel is sold in Canada, Australia, NZ, UK, the USA and Ireland as an over-the-counter acne remedy. If a twice-daily application causes the skin to dry excessively, one may use once a day or every other day.Nicotinamide is highly not recommended for acne in pregnancy or nursing women.
A comedo is a clogged hair follicle (pore) in the skin. Keratin combines with oil to block the follicle. A comedo can be open (blackhead) or closed by skin (whitehead) and occur with or without acne. The word comedo comes from the Latin comedere, meaning 'to eat up', and was historically used to describe parasitic worms; in modern medical terminology, it is used to suggest the worm-like appearance of the expressed material.
Bausch Health Companies Inc. is a multinational specialty pharmaceutical company based in Laval, Quebec, Canada. It develops, manufactures and markets pharmaceutical products and branded generic drugs, primarily for skin diseases, gastrointestinal disorders, eye health and neurology. Bausch Health owns Bausch & Lomb, a supplier of eye health products.
Galderma S.A. is a Swiss pharmaceutical company specializing in dermatological treatments and skin care products. Formerly a subsidiary of L'Oréal and Nestlé, it has been held by a consortium of private institutional investors since 2019.
Benzoyl peroxide/clindamycin is a topical gel used for the treatment of acne. It is a combination of clindamycin, an antibiotic, and benzoyl peroxide, an antiseptic. All formulations are prescription drugs.
Rohto Pharmaceutical Co., Ltd. is a multinational fast-moving consumer goods and pharmaceutical corporation headquartered in Ikuno-ku, Osaka, Japan, with a presence in North America, Europe and Asia. The company is listed on the stock exchange having posted steady increases in revenues from ¥95,619 million in 2006 to ¥120,292 million in 2011. Skin Care contributes to 61.3% of the revenues while Eye Care contributes to 21% of their sales.
Amcinonide is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis. Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity.
Bradley Pharmaceuticals was a pharmaceutical company headquartered in Fairfield Township, Essex County, New Jersey. The company was founded in 1985 by Daniel Glassman who was also its CEO.
Medicis Pharmaceutical is a medical cosmetics company based in Bridgewater, New Jersey. It is a subsidiary of Valeant Pharmaceuticals, which acquired the company in 2012. Medicis is known for products such as Solodyn and Ziana for treating acne, and for Restylane and Dysport for treating facial wrinkles.
Sun Pharmaceutical Industries Limited is No. 4th Global and no. 1 Indian multinational pharmaceutical company headquartered in Mumbai, Maharashtra, that manufactures and sells pharmaceutical formulations and active pharmaceutical ingredients (APIs) primarily in India and the United States. The company offers formulations in various therapeutic areas, such as cardiology, psychiatry, neurology, gastroenterology and diabetology. It also provides APIs such as warfarin, carbamazepine, etodolac, and clorazepate, as well as anti-cancers, steroids, peptides, sex hormones, and controlled substances.
A pimple is a kind of comedo that results from excess sebum and dead skin cells getting trapped in the pores of the skin. In its aggravated state, it may evolve into a pustule or papules. Pimples can be treated by acne medications, antibiotics, and anti-inflammatories prescribed by a physician, or various over the counter remedies purchased at a pharmacy.
Stiefel Laboratories is an American dermatological pharmaceutical company, with its global headquarters in Research Triangle Park, North Carolina. It makes products such as Duac and Oilatum. Stiefel was acquired by GlaxoSmithKline at a price of $2.9 billion. The company was founded in 1847 by John David Stiefel, Ferdinand von Hebra and Paul Unna, who initially created medicated soaps.
CFR Pharmaceuticals, now owned by Abbott Laboratories, is a Chilean pharmaceutical company engaged in the development, production, and sale of pharmaceutical drugs in 15 Latin American countries such as Argentina, Bolivia, Chile, Colombia, Costa Rica, Ecuador, Paraguay, Peru, Venezuela and others and in Vietnam in Asia. The company is one of the largest Pharmaceutical companies in Latin America.
Yoram Harth is an Israeli dermatologist and inventor. He co-invented blue light acne vulgaris phototherapy, as well as a radio frequency device for home treatment for wrinkle reduction.
References
- ↑ "DUSA Pharmaceuticals Closes Acquisition of Sirius Laboratories". BNET. 2006-04-14. Retrieved 2008-08-26.CS1 maint: discouraged parameter (link)
- ↑ Caraco Pharmaceutical Laboratories Announces Successful Tender Offer To Acquire DUSA. and Archived 2015-09-12 at the Wayback Machine