Deborah (Debbie) Jarvis | |
---|---|
Born | UK |
Citizenship | British |
Known for | Epidemiology of Asthma Epidemiology of Allergy |
Scientific career | |
Fields | Public health |
Institutions | National Heart & Lung Institute Imperial College London |
Website | https://www.imperial.ac.uk/people/d.jarvis |
Deborah (Debbie) Jarvis is a British emeritus professor of public health at the National Heart and Lung Institute, Imperial College London. [1] She is an authority on the epidemiology of asthma in adults. [2]
Jarvis obtained both her MB.BS degree and MD (postgraduate research degree) from University of London, and trained in public health in South East Thames. The early part of her research career was spent at King's College London. She moved to Imperial College London in 2006.
Jarvis main research focus has been on identifying lifestyle and environmental factors, including air pollution, that could determine whether adults have or develop allergy, asthma or chronic obstructive pulmonary disease. [3] She is project lead of the European Community Respiratory Health Survey (ECRHS) [4] and principal investigator of the Ageing Lungs in European Cohorts study. [5] She was member of the Committee on the Medical Effects of Air Pollutants (COMEAP), [6] and served as Chair of the Epidemiology group of the Occupation and Epidemiology Assembly of the European Respiratory Society. [7]
Mold health issues refer to the harmful health effects of molds and their mycotoxins.
Asthma is a common long-term inflammatory disease of the airways of the lungs. Asthma occurs when allergens, pollen, dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise.
Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, coughing, a runny nose, shortness of breath, or swelling. Note that food intolerances and food poisoning are separate conditions.
An allergen is an otherwise harmless substance that triggers an allergic reaction in sensitive individuals by stimulating an immune response.
Sputum is mucus that is coughed up from the lower airways. In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations of respiratory systems.
House dust mites are various species of acariform mites belonging to the family Pyroglyphidae that are found in association with dust in dwellings. They are known for causing allergies.
Chlamydia pneumoniae is a species of Chlamydia, an obligate intracellular bacterium that infects humans and is a major cause of pneumonia. It was known as the Taiwan acute respiratory agent (TWAR) from the names of the two original isolates – Taiwan (TW-183) and an acute respiratory isolate designated AR-39. Briefly, it was known as Chlamydophila pneumoniae, and that name is used as an alternate in some sources. In some cases, to avoid confusion, both names are given.
Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment. Allergic diseases are clinical manifestations of such inappropriate, atopic responses.
Exercise-induced bronchoconstriction (EIB) occurs when the airways narrow as a result of exercise. This condition has been referred to as exercise-induced asthma (EIA); however, this term is no longer preferred. While exercise does not cause asthma, it is frequently an asthma trigger.
Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response of the immune system to the fungus Aspergillus. It occurs most often in people with asthma or cystic fibrosis. Aspergillus spores are ubiquitous in soil and are commonly found in the sputum of healthy individuals. A. fumigatus is responsible for a spectrum of lung diseases known as aspergilloses.
Occupational asthma is new onset asthma or the recurrence of previously quiescent asthma directly caused by exposure to an agent at workplace. It is an occupational lung disease and a type of work-related asthma. Agents that can induce occupational asthma can be grouped into sensitizers and irritants.
Bronchial hyperresponsiveness is a state characterised by easily triggered bronchospasm.
Asthma is a common pulmonary condition defined by chronic inflammation of respiratory tubes, tightening of respiratory smooth muscle, and episodes of bronchoconstriction. The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. According to the World Health Organization, asthma affects 235 million people worldwide. There are two major categories of asthma: allergic and non-allergic. The focus of this article will be allergic asthma. In both cases, bronchoconstriction is prominent.
As of 2011, approximately 235 million people worldwide were affected by asthma, and roughly 250,000 people die per year from asthma-related causes. Low and middle income countries make up more than 80% of the mortality. Prevalences vary between countries from 1% to 18%. Asthma tends to be more prevalent in developed than in developing countries. Rates are lower in Asia, Eastern Europe, and Africa. Within developed countries it is more common among those who are economically disadvantaged, but in contrast in developing countries it is more common amongst the affluent. The reason for these differences is not well known.
GA²LEN, or Global Allergy and Asthma European Network, is a consortium of leading European research centres specialized in allergic diseases, including asthma. Funded by the European Union under the 6th Framework Programme, GA²LEN addresses the growing public health concern of allergic diseases.
Dehydrogenase/reductase member 7 is a protein that in humans is encoded by the DHRS7 gene.
Stephanie J. London is an American epidemiologist and physician-scientist specializing in environmental health, respiratory diseases, and genetic susceptibility. She is the deputy chief of the epidemiology branch at the National Institute of Environmental Health Sciences.
Peter Burney is a British epidemiologist. He is emeritus professor of respiratory epidemiology and public health at the National Heart and Lung Institute, Imperial College London. He is a Fellow of the Academy of Medical Sciences since 2001.
Frank Erwin Speizer is an American physician and epidemiologist, currently Professor of Environmental Health and Environmental Science at Harvard T.H. Chan School of Public Health, and Edward H. Kass Distinguished Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School. He is best known for his work on two major epidemiological cohort studies: the Nurses' Health Study, which explored women's illnesses and health risk factors, and the Harvard Six Cities study, which definitively linked air pollution to higher death rates in urban areas.