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In chemistry, a reagent or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms reactant and reagent are often used interchangeably, but reactant specifies a substance consumed in the course of a chemical reaction. Solvents, though involved in the reaction mechanism, are usually not called reactants. Similarly, catalysts are not consumed by the reaction, so they are not reactants. In biochemistry, especially in connection with enzyme-catalyzed reactions, the reactants are commonly called substrates.
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Craig M. Crews is an American scientist at Yale University. He is the John C. Malone Professor of Molecular, Cellular, and Developmental Biology, and also holds joint appointments in the departments of Chemistry and Pharmacology. Crews is the Executive Director of the Yale Center for Molecular Discovery and a former Editor of the journal Cell Chemical Biology. His research interests focus on chemical biology, particularly on controlled proteostasis. Crews is a pioneer in the field of targeted protein degradation and his lab's research led to the development of the anti-cancer drug carfilzomib (Kyprolis). He is the founder of Arvinas, the first biotechnology company to bring PROTAC drugs into clinical trials.In 2019, he was named an American Cancer Society Research Professor at the Yale University.
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Jonathan Baell is an Australian medicinal chemist. He is a research professor in medicinal chemistry at the Monash Institute of Pharmaceutical Sciences (MIPS), the Director of the Australian Translational Medicinal Chemistry Facility and a Chief Investigator at the ARC Centre for Fragment-Based Design. He is also the President of the International Chemical Biology Society. His research focuses on the early stages of drug discovery, including high-throughput screening (HTS) library design, hit-to-lead and lead optimization for the treatment of a variety of diseases, such as malaria and neglected diseases.
References
- ↑ Weintraub, Karen (5 March 2016). "Derek Lowe: Chemist puts a human face on drug development". STAT.
- ↑ "Derek Lowe". Chemistry World.
- ↑ "Odyssey Medal: Derek Lowe". Hendrix College. 2014.
- 1 2 "Derek Lowe". LinkedIn. Retrieved 29 May 2018.
- ↑ Secko, David (August 2005). "The Power of the Blog". The Scientist. Archived from the original on 2011-05-14.
- ↑ "The oldest science blog of all? | Gene Expression | Discover Magazine". Blogs.discovermagazine.com. 2010-08-24. Retrieved 2012-02-22.
- 1 2 Raber, Linda R. (June 19, 2006). "Moving Away From Target-Based Discovery". Chemical & Engineering News.
- ↑ Jarvis, Lisa (24 August 2010). "Pharma Blogging Panel at ACS Boston". The Haystack.
- ↑ "Foods Ingredients Banned Outside the US". ABC News. 26 June 2013.
- ↑ Nosowitz, Dan (June 21, 2013). "Chemist Says BuzzFeeᴅ Article About Food Chemistry Has "Serial Stupidities"". Popular Science.
- ↑ Jogalekar, Ashutosh (July 11, 2013). "Where's the chemistry lobby? On why we need a National Center for Chemical Education". Scientific American Blog Network.
- ↑ Baum, Rudy M. (3 May 2010). "C&EN In The Blogosphere". Chemical & Engineering News. 88 (18): 3. doi: 10.1021/cen-v088n018.p003 .
- ↑ Lieu, Chris (28 March 2017). "BioCentury - Lowe parts ways with Vertex amid reorganization". Biocentury.
- ↑ Chemjobber (November 20, 2017). "Layoffs and the midcareer chemist". Chemical & Engineering News. 95 (46).
