HIV/AIDS originated in Africa during early 20th century and is a major public health concern and cause of death in many African countries. AIDS rates varies significantly between countries, though the majority of cases are concentrated in Southern Africa. Although the continent is home to about 15.2 percent of the world's population, more than two-thirds of the total infected worldwide – some 35 million people – were Africans, of whom 15 million have already died. Eastern and Southern Africa alone accounted for an estimate of 60 percent of all people living with HIV and 70 percent of all AIDS deaths in 2011. The countries of Eastern and Southern Africa are most affected, AIDS has raised death rates and lowered life expectancy among adults between the ages of 20 and 49 by about twenty years. Furthermore, the life expectancy in many parts of Africa is declining, largely as a result of the HIV/AIDS epidemic with life-expectancy in some countries reaching as low as thirty-nine years.
The Treatment Action Campaign (TAC) is a South African HIV/AIDS activist organisation which was co-founded by the HIV-positive activist Zackie Achmat in 1998. TAC is rooted in the experiences, direct action tactics and anti-apartheid background of its founder. TAC has been credited with forcing the reluctant government of former South African President Thabo Mbeki to begin making antiretroviral drugs available to South Africans.
Masiphumelele is a township on the Cape Peninsula, South Africa, situated between Kommetjie, Capri Village and Noordhoek.
HIV/AIDS is one of the most serious health concerns in South Africa. The country has the highest number of people afflicted with HIV of any country, and the fourth-highest adult HIV prevalence rate, according to the 2019 United Nations statistics.
The very high rate of HIV infection experienced in Uganda during the 1980s and early 1990s created an urgent need for people to know their HIV status. The only option available to them was offered by the National Blood Transfusion Service, which carries out routine HIV tests on all the blood that is donated for transfusion purposes. The great need for testing and counseling resulted in a group of local non-governmental organizations such as The AIDS Support Organisation (TASO), Uganda Red Cross, Nsambya Home Care, the National Blood Bank, the Uganda Virus Research Institute together with the Ministry of Health establishing the AIDS Information Centre in 1990. This organization worked to provide HIV testing and counseling services with the knowledge and consent of the client involved.
Ivan Peter Toms was a South African physician, who battled the Apartheid era government as a prominent anti-Apartheid and anti-conscription activist. He opposed conscription by the South African Defence Force, and was a co-founder of the End Conscription Campaign. He ran a clinic in the Crossroads shanty town where he was the only physician for 60,000 people. He went on a hunger strike in 1985 after the government decided to bulldoze the settlement. Toms was also involved with gay rights activism in South Africa and was a founding member of the Lesbians and Gays Against Oppression. At the time of his death in 2008, Toms was serving as the Director of Health for the city of Cape Town, South Africa.
The Royal Society Africa Prize has been awarded by the Royal Society since 2006 to African-based researchers at the start of their career who are making innovative contributions to the biological sciences in Africa. £60,000 is awarded as a grant for the recipient to carry out a research project that is linked to an African centre of scientific excellence, normally a University or equivalent research centre, and a further £5,000 is given directly to the prizewinner.
HIV/AIDS in Eswatini was first reported in 1986 but has since reached epidemic proportions. As of 2016, Eswatini had the highest prevalence of HIV among adults aged 15 to 49 in the world (27.2%).
HIV/AIDS in Bolivia has a less than 1 percent prevalence of Bolivia's adult population estimated to be HIV-positive. Bolivia has one of the lowest HIV prevalence rates in the Latin America and Caribbean region.
In 2016, the prevalence rate of HIV/AIDS in adults aged 15–49 was 0.3%, relatively low for a developing country. This low prevalence has been maintained, as in 2006, the HIV prevalence in Mexico was estimated at around 0.3% as well. The infected population is remains mainly concentrated among high risk populations, men who have sex with other men, intravenous drug users, and commercial sex workers. This low national prevalence is not reflected in the high-risk populations. The prison population in Mexico, faces a fairly similar low rate of around 0.7%. Among the population of prisoners, around 2% are known to be infected with HIV. Sex workers, male and female, face an HIV prevalence of around 7%. Identifying gay men and men who have sex with other men have a prevalence of 17.4%. The highest risk-factor group is identifying transgender people; about 17.4% of this population is known to be infected with HIV. Around 90% of new infections occur by sex-related methods of transmission. Of these known infected populations, around 60% of living infected people are known to be on anti-retroviral therapy (ART).
In South Africa, private and public health systems exist in parallel. The public system serves the vast majority of the population. Authority and service delivery are divided between the national Department of Health, provincial health departments, and municipal health departments.
South Africa's HIV/AIDS epidemic, which is among the most severe in the world, is concentrated in its townships, where many black South Africans live due to the lingering effects of the Group Areas Act.
The Desmond Tutu TB Centre, also referred to as the DTTC or Desmond Tutu Tuberculosis Centre, is a research facility committed to raising awareness about tuberculosis and providing medical treatment and solutions to TB patients in South Africa. Founded in 2003 by Professor Nulda Beyers as the Centre for Tuberculosis Research and Education, the centre came under the patronage of Archbishop Desmond Tutu, Archbishop of South Africa and former TB survivor and, in 2005, changed its name to reflect the event. Since then, the DTTC has worked alongside Desmond Tutu to combat the health issue of TB in South Africa. It is currently directed by Professor Beyers.
Duncan Village Day Hospital is a Provincial government funded day hospital situated Braelyn in East London, Eastern Cape in South Africa. Patients are attended to by doctors as well as registered nurse practitioners.
Madwaleni Hospital is a Provincial government funded hospital near rural Elliotdale, Eastern Cape in South Africa.
The AIDS Support Organization (TASO) is an indigenous HIV and AIDS service initiative, registered in Uganda as a non-governmental organisation. It is a pioneer non-public actor in the HIV and AIDS response in Uganda. TASO is a membership organisation with over 4,000 subscriber members.
Glenda Elisabeth GrayMB BCh, FC Paeds, DSc (hc), is a South African physician, scientist and activist specializing in the care of children and in HIV medicine. In 2012, she was awarded South Africa's highest honour, the Order of Mapungubwe (Silver). She became the first female president of the South African Medical Research Council in 2014, was recognized as one of the "100 Most Influential People" by Time in 2017 and was listed amongst "Africa's 50 Most Powerful Women" by Forbes Africa in 2020. Her research expertise involves developing microbicides for sexually transmitted diseases and HIV vaccines.
Treatment as prevention (TasP) is a concept in public health that promotes treatment as a way to prevent and reduce the likelihood of HIV illness, death and transmission from an infected individual to others. Expanding access to earlier HIV diagnosis and treatment as a means to address the global epidemic by preventing illness, death and transmission was first proposed in 2000 by Garnett et al. The term is often used to talk about treating people that are currently living with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) to prevent illness, death and transmission. Although some experts narrow this to only include preventing infections, treatment prevents illnesses such as tuberculosis and has been shown to prevent death. The dual impact on well-being and its 100% effectiveness in reducing transmission makes TasP the most important element in the HIV prevention toolkit. In relation to HIV, antiretroviral therapy (ART) is a three or more drug combination therapy that is used to decrease the viral load, or the measured amount of virus, in an infected individual. Such medications are used as a preventative for infected individuals to not only spread the HIV virus to their negative partners but also improve their current health to increase their lifespans. Other names for ART include highly active antiretroviral therapy (HAART), combination antiretroviral therapy (cART), triple therapy and triple drug cocktail. When taken correctly, ART is able to diminish the presence of the HIV virus in the bodily fluids of an infected person to a level of undetectability. Undetectability ensures that infection does not necessarily have an effect on a person's general health, and that there is no longer a risk of passing along HIV to others. Consistent adherence to an ARV regimen, monitoring, and testing are essential for continued confirmed viral suppression. Treatment as prevention rose to great prominence in 2011, as part of the HPTN 052 study, which shed light on the benefits of early treatment for HIV positive individuals.
Linda-Gail Bekker MBChB, DTMH, DCH, FCP(SA) is a Professor of Medicine and Chief Operating Officer of the Desmond Tutu HIV Foundation. She is also Director of the Desmund Tutu HIV Centre at the University of Cape Town. She is a Past President of the International AIDS Society (2016-18).
Elizabeth Anne Bukusi FAAS is a research professor working within the field of obstetrics and gynaecology, and global health. Bukusi's main areas of research focus around sexually transmitted infections, women's health, reproductive health, and HIV care, prevention and treatment. Bukusi is the Chief Research Officer at the Kenya Medical Research Institute (KEMRI) and led a "landmark" study on the use of PrEP in Kenya.
