Diascopy

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Diascopy of a red dot basal cell carcinoma on the left mid back of a 74-year-old female. The red dot basal cell carcinoma on the left mid back is circled; the tumor blanches when a glass microscope slide is pressed against it. From a case series by Philip R Cohen, 2017. Diascopy of a red dot basal cell carcinoma on the left mid back of a 74-year-old female.jpg
Diascopy of a red dot basal cell carcinoma on the left mid back of a 74-year-old female. The red dot basal cell carcinoma on the left mid back is circled; the tumor blanches when a glass microscope slide is pressed against it. From a case series by Philip R Cohen, 2017.

Diascopy is a test for blanchability performed by applying pressure with a finger or glass slide and observing color changes. [2] [3] [4] [5]

It is used to determine whether a lesion is vascular (inflammatory or congenital), nonvascular (nevus), or hemorrhagic (petechia or purpura). Hemorrhagic lesions and nonvascular lesions do not blanch ("negative diascopy"); inflammatory lesions do ("positive diascopy"). Diascopy is sometimes used to identify sarcoid skin lesions, which, when tested, turn an apple jelly color.

Diascopy with glassware is used as a method of diagnosing bacterial meningitis, as the rashes caused by the illness are non-blanching. [6]

References

  1. ↑ Cohen PR (March 2017). "Red Dot Basal Cell Carcinoma: Report of Cases and Review of This Unique Presentation of Basal Cell Carcinoma". Cureus. 9 (3): e1110. doi: 10.7759/cureus.1110 . PMC   5408973 . PMID   28465868.
  2. ↑ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 29. ISBN   1-4160-3185-5.
  3. ↑ Goldman, L.; Plotnick, H.; Balinkin, I. (May 9, 1957). "Investigative and clinical studies with diascopy in dermatology". Archives of Dermatology. 75 (5): 699–705. doi:10.1001/archderm.1957.01550170067012. PMID   13410135.
  4. ↑ D, Pérez-López; M, Peña-Cristóbal; EM, Otero-Rey; I, Tomás; A, Blanco-Carrión (October 1, 2016). "Clinical value of diascopy and other non-invasive techniques on differential diagnosis algorithms of oral pigmentations: A systematic review". Journal of Clinical and Experimental Dentistry. 8 (4): e448 –e458. doi:10.4317/jced.53005. PMC   5045694 . PMID   27703615.
  5. ↑ Rudd, M.; Eversole, R.; Carpenter, W. (March 9, 2001). "Diascopy: a clinical technique for the diagnosis of vascular lesions". General Dentistry. 49 (2): 206–209. PMID   12004702.
  6. ↑ "Meningitis Glass Test - Meningitis Rash Test". Meningitis Now. Retrieved 2025-05-10.


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