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In biology, the epigenome of an organism is the collection of chemical changes to its DNA and histone proteins that affects when, where, and how the DNA is expressed; these changes can be passed down to an organism's offspring via transgenerational stranded epigenetic inheritance. Changes to the epigenome can result in changes to the structure of chromatin and changes to the function of the genome.
The ABC model of flower development is a scientific model of the process by which flowering plants produce a pattern of gene expression in meristems that leads to the appearance of an organ oriented towards sexual reproduction, a flower. There are three physiological developments that must occur in order for this to take place: firstly, the plant must pass from sexual immaturity into a sexually mature state ; secondly, the transformation of the apical meristem's function from a vegetative meristem into a floral meristem or inflorescence; and finally the growth of the flower's individual organs. The latter phase has been modelled using the ABC model, which aims to describe the biological basis of the process from the perspective of molecular and developmental genetics.
Usha Vijayraghavan is an Indian molecular biologist. She is on the faculty of the Department of Microbiology and Cell Biology, at the Indian Institute of Science. Her major research interests are Molecular Genetics, Plant Development.
Arabidopsis thaliana is a first class model organism and the single most important species for fundamental research in plant molecular genetics.
Kenneth S. Zaret is a professor in the Department of Cell and Developmental Biology at the Perelman School of Medicine, University of Pennsylvania, and Director of the Institute for Regenerative Medicine at UPenn. He is a recipient of the Hans Popper Basic Science Award from the American Association for the Study of Liver Diseases and the American Liver Foundation, a fellow of the American Association for the Advancement of Science, and a member of the American Academy of Arts and Sciences, the European Molecular Biology Organization, and the National Academy of Sciences.
Karmella Ann Haynes is a biomedical engineer and associate professor at the Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University. She researches how chromatin is used to control cell development in biological tissue.
Beronda Montgomery is a writer, science communicator, and researcher. In 2022, she moved to Grinnell College as professor of biology and vice president for academic affairs and dean of the college. Prior to Grinnell, Montgomery served as Michigan State University Foundation Professor in the Departments of Biochemistry & Molecular Biology and of Microbiology & Molecular Genetics. She was also a member of the MSU-DOE Plant Research Laboratory. Her research group investigates how photosynthetic organisms adapt to changes in their environment. Her scholarship extends beyond biology and into studying mentorship and faculty development to develop evidence-based strategies to foster equity and inclusion in academia. Together with Tanisha Williams and other members of the Black Botanists Week organizing committee, Montgomery co-founded and co-organizes Black Botanists Week.
Manolis Kellis is a professor of Computer Science and Computational Biology at the Massachusetts Institute of Technology (MIT) and a member of the Broad Institute of MIT and Harvard. He is the head of the Computational Biology Group at MIT and is a Principal Investigator in the Computer Science and Artificial Intelligence Lab (CSAIL) at MIT.
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Zhiping Weng is the Li Weibo Professor of biomedical research and chair of the program in integrative biology and bioinformatics at the University of Massachusetts Medical School. She was awarded Fellowship of the International Society for Computational Biology (ISCB) in 2020 for outstanding contributions to computational biology and bioinformatics.
Katrina T. Forest is an American biologist who is the EB Fred Professor of Bacteriology and Chair in the Department of Bacteriology at the University of Wisconsin–Madison. Her research considers the use of structural biology to better understand pathogenesis. Forest is a Fellow of the American Society for Microbiology.
Erika L F. Holzbaur is an American biologist who is the William Maul Measey Professor of Physiology at University of Pennsylvania Perelman School of Medicine. Her research considers the dynamics of organelle motility along cytoskeleton of cells. She is particularly interested in the molecular mechanisms that underpin neurodegenerative diseases.
Marisa Bartolomei is an American cell biologist, the Perelman Professor of Cell and Developmental Biology and Co-Director of the Epigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania. Her research considers epigenetic processes including genomic imprinting. She was elected to the National Academy of Sciences in 2021.
Elizabeth Haswell is an American biologist who is a professor and Howard Hughes Medical Institute-Simons Faculty Scholar at the Washington University in St. Louis. She was elected Fellow of the American Association for the Advancement of Science in 2021.
Elaine Munsey Tobin is a professor of molecular, cell, and developmental biology at the University of California, Los Angeles (UCLA). Tobin is recognized as a Pioneer Member of the American Society of Plant Biologists (ASPB).
Chantell Skye Evans is an American cell biologist who is a professor at Duke University. Her research looks to understand the dynamical processes of mitochondria and their role in neurodegenerative disease. In 2022, Popular Science named her as one of their "Brilliant 10" U.S. scientists and engineers.
Jane Silverthorne was a biologist based in America who worked on plant development in response to light. She became a program officer at the National Science Foundation in the USA as well as a Senior Policy Analyst for the White House Office on Science and Technology.
Doris Howell was an American physician who specialized in pediatric oncology. She became known as the "mother of hospice," for her pioneering work in palliative care.
Danica Galonić Fujimori is a Serbian-American chemical biologist who is a professor at the University of California, San Francisco. Her research considers nucleic acid synthesis and tissue engineering. In the search for new therapeutics and vaccines, she has studied the interactions between ribosomes and SARS-CoV-2.
Stacey Harmer is a chronobiologist whose work centers on the study of circadian rhythms in plants. Her research focuses on the molecular workings of the plant circadian clock and its influences on plant behaviors and physiology. She is a professor in the Department of Plant Biology at the University of California, Davis.
References
- 1 2 3 "Doris Wagner | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of Pennsylvania". www.med.upenn.edu. Retrieved 2022-04-18.
- ↑ "Doris Wagner | Department of Biology". www.bio.upenn.edu. Retrieved 2022-04-18.
- ↑ Wagner, Doris (1995). Functional and structural analysis of Phytochrome B: a novel photoreceptor (Thesis). OCLC 34538971.
- ↑ "Meyerowitz Lab - Group photos from the 90's". plantlab.caltech.edu. Retrieved 2022-04-18.
- ↑ "NSF Award Search: Award # 0925071 - RCN: Establishment of an Epigenomics of Plants International Consortium (EPIC)". www.nsf.gov. Retrieved 2022-04-18.
- ↑ "First ever 'pioneer' factor found in plants enables cells to change their fate". EurekAlert!. Retrieved 2022-04-18.
- ↑ "DR. DORIS WAGNER RECEIVED THE 2019 FELLOW OF AMERICAN SOCIETY OF PLANT BIOLOGISTS AWARD | Wagner Lab". web.sas.upenn.edu. Retrieved 2022-04-18.
- ↑ "Editorial Board - Current Opinion in Plant Biology - Journal - Elsevier". www.journals.elsevier.com. Retrieved 2022-04-18.
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