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Dotmatics is an R&D scientific software company used by scientists in the R&D process that help them be more efficient in their efforts to innovate. Founded in 2005, the company's primary office is in Boston with 14 offices around the globe. [1] In March 2021, Insightful Science acquired Dotmatics. [2] In April 2022, the two companies consolidated under the Dotmatics brand with Insightful Science CEO Thomas Swalla leading the new Dotmatics. [3] Dotmatics' software is used by 2 million scientists and researchers and 10,000 customers. [4]
Dotmatics offers a cloud-based data management platform to support the R&D process and a series of software applications used by scientists that include GraphPad Prism, SnapGene, Geneious Prime, Geneious Biologics, Lab Archives, OMIQ, Protein Metrics, nQuery, Cytapex Bioinformatics, De Novo, SoftGenetics [5] , and M-Star [6] . [7]
In October 2023, Dotmatics released a multimodal drug discovery platform named Luma. Luma is a low-code SaaS platform that aggregates relevant data across instruments and software into clean data structures for AI and ML-based analysis. [4]
Dotmatics is backed by Insight Partners, a venture capital and private equity firm. [8]
Dotmatics' origins trace back to Merck Sharp and Dohme, a multinational pharmaceutical company, where, in the early 2000s, Merck staff developed what later became Dotmatics' browser and gateway software. Dotmatics Limited was founded in 2005 as a spin-out [9] when Merck closed the site. The company was established with the intent to address the information needs of scientists in the biotech/pharma space. [6]
Dotmatics develops web-based tools for querying, browsing, managing, and sharing scientific data and documents. [23]
The Informatics Suite is all the software packaged into one integrated suite. [27]
Bioinformatics is an interdisciplinary field of science that develops methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics uses biology, chemistry, physics, computer science, computer programming, information engineering, mathematics and statistics to analyze and interpret biological data. The subsequent process of analyzing and interpreting data is referred to as computational biology.
A Laboratory management system (LIMS), sometimes referred to as a laboratory information system (LIS) or laboratory management system (LMS), is a software-based solution with features that support a modern laboratory's operations. Key features include—but are not limited to—workflow and data tracking support, flexible architecture, and data exchange interfaces, which fully "support its use in regulated environments". The features and uses of a LIMS have evolved over the years from simple sample tracking to an enterprise resource planning tool that manages multiple aspects of laboratory informatics.
MDL Information Systems, Inc. was a provider of R&D informatics products for the life sciences and chemicals industries. The company was launched as a computer-aided drug design firm in January 1978 in Hayward, California. The company was acquired by Symyx Technologies, Inc. in 2007. Subsequently Accelrys merged with Symyx. The Accelrys name was retained for the combined company. In 2014 Accelrys was acquired by Dassault Systemes. The Accelrys business unit was renamed BIOVIA.
BIOVIA is a software company headquartered in the United States, with representation in Europe and Asia. It provides software for chemical, materials and bioscience research for the pharmaceutical, biotechnology, consumer packaged goods, aerospace, energy and chemical industries.
ChemSpider is a freely accessible online database of chemicals owned by the Royal Society of Chemistry. It contains information on more than 100 million molecules from over 270 data sources, each of them receiving a unique identifier called ChemSpider Identifier.
Chemaxon is a cheminformatics and bioinformatics software development company, headquartered in Budapest with 250 employees. The company also has offices in Cambridge, San Diego, Basel and in Prague. and it has distributors in China, India, Japan, South Korea, Singapore, and Australia.
Galaxy is a scientific workflow, data integration, and data and analysis persistence and publishing platform that aims to make computational biology accessible to research scientists that do not have computer programming or systems administration experience. Although it was initially developed for genomics research, it is largely domain agnostic and is now used as a general bioinformatics workflow management system.
GraphPad Software Inc. was a privately held software development corporation until its acquisition by Insight Partners in 2017. The company was named Insightful Science, which itself merged with Dotmatics in 2021. The original software was written by Harvey Motulsky in 1989 and it was co-founded by Motulsky and Earl Beutler. The company operates in California. Its products include the 2D scientific graphing, biostatistics, curve fitting software GraphPad Prism and the free, web-based statistical calculation software, GraphPad QuickCalcs.
KNIME, the Konstanz Information Miner, is a free and open-source data analytics, reporting and integration platform. KNIME integrates various components for machine learning and data mining through its modular data pipelining "Building Blocks of Analytics" concept. A graphical user interface and use of JDBC allows assembly of nodes blending different data sources, including preprocessing, for modeling, data analysis and visualization without, or with only minimal, programming.
LabKey Server is a software suite available for scientists to integrate, analyze, and share biomedical research data. The platform provides a secure data repository that allows web-based querying, reporting, and collaborating across a range of data sources. Specific scientific applications and workflows can be added on top of the basic platform and leverage a data processing pipeline.
TACTIC is a web-based, open source workflow platform and digital asset management system supported by Southpaw Technology in Toronto, ON. Designed to optimize busy production environments with high volumes of content traffic, TACTIC applies business or workflow logic to combined database and file system management. Using elements of digital asset management, production asset management and workflow management, TACTIC tracks the creation and development of digital assets through production pipelines. TACTIC is available under both commercial and open-source licenses, and also as a hosted cloud service through Amazon Web Services Marketplace.
LabLynx, Inc. is a privately owned, funded, and managed American corporation that develops, supports, and markets laboratory information management system (LIMS) solutions. Its primary offerings over the years have included webLIMS and ELab. The company’s primary clients include laboratories in the agriculture, clinical, environmental, forensics, health care, and manufacturing industries, including government agencies. The company is known for introducing one of the first browser-based LIMS products in 1997 and being in the laboratory informatics industry for decades.
BioMart is a community-driven project to provide a single point of access to distributed research data. The BioMart project contributes open source software and data services to the international scientific community. Although the BioMart software is primarily used by the biomedical research community, it is designed in such a way that any type of data can be incorporated into the BioMart framework. The BioMart project originated at the European Bioinformatics Institute as a data management solution for the Human Genome Project. Since then, BioMart has grown to become a multi-institute collaboration involving various database projects on five continents.
ChemWindow is a chemical structure drawing molecule editor and publishing program now published by John Wiley & Sons as of 2020, originally developed by Bio-Rad Laboratories, Inc. It was first developed by SoftShell International in the 1990s. Bio-Rad acquired this technology in 1996 and eventually made it part of their KnowItAll software product line, offering a specific ChemWindow edition of their software for structure drawing and publishing. They have also incorporated ChemWindow structure drawing components into their KnowItAll spectroscopy software packages with their DrawIt, ReportIt, and MineIt tools.
Pipeline Pilot is a desktop software program sold by Dassault Systèmes for processing and analyzing data. Originally used in the natural sciences, the product's basic ETL and analytics capabilities have broadened over time. The product is now used for data science, ETL, reporting, prediction, and analytics in a number of sectors. The main feature of the program is the ability to design data workflows using a graphical user interface. It is an example of visual and dataflow programming and has use in a variety of settings, such as cheminformatics and QSAR, Next Generation Sequencing, image analysis, and text analytics. It is not an 'object oriented' programming language.
A bioinformatics workflow management system is a specialized form of workflow management system designed specifically to compose and execute a series of computational or data manipulation steps, or a workflow, that relate to bioinformatics.
CARTO is a software as a service (SaaS) spatial analysis platform that provides GIS, web mapping, data visualization, spatial analytics, and spatial data science features. The company is positioned as a Location Intelligence platform due to its tools for geospatial data analysis and visualization that do not require advanced GIS or development experience. As a cloud-native platform, CARTO runs natively on cloud data warehouse platforms overcoming any previous limits on data scale for spatial workloads.
Linguamatics, headquartered in Cambridge, England, with offices in the United States and UK, is a provider of text mining systems through software licensing and services, primarily for pharmaceutical and healthcare applications. Founded in 2001, the company was purchased by IQVIA in January 2019.
Project Jupyter is a project to develop open-source software, open standards, and services for interactive computing across multiple programming languages.
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Alberto Bresciani, Head of Screening Technologies at IRBM Science Park said '...data management and data analysis across a set of highly diverse projects.'