ERVK6

ERVK-6
Identifiers
Aliases	ERVK-6 , HERV-K(C7), HERV-K108, K-Rev, c-orf, cORF, endogenous retrovirus group K member 6, endogenous retrovirus group K member 6, envelope, envK2
External IDs	OMIM: 605626; GeneCards: ERVK-6; OMA:ERVK-6 - orthologs
Orthologs Species Human Mouse Entrez 64006 n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) NM_001007236 n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search [1] n/a
Wikidata
View/Edit Human

HERV-K_19q12 provirus ancestral Pol protein is a protein that in humans is encoded by the ERVK6 gene. ^{[2] [3] [4]}

References

1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
2. Mayer J, Sauter M, Racz A, Scherer D, Mueller-Lantzsch N, Meese E (Mar 1999). "An almost-intact human endogenous retrovirus K on human chromosome 7". Nat Genet. 21 (3): 257–8. doi:10.1038/6766. PMID   10080172. S2CID   38753809.
3. Reus K, Mayer J, Sauter M, Scherer D, Muller-Lantzsch N, Meese E (Jun 2001). "Genomic organization of the human endogenous retrovirus HERV-K(HML-2.HOM) (ERVK6) on chromosome 7". Genomics. 72 (3): 314–20. doi:10.1006/geno.2000.6488. PMID   11401447.
4. "Entrez Gene: ERVK6 endogenous retroviral sequence K, 6".

Further reading

• Löwer R, Tönjes RR, Korbmacher C, et al. (1995). "Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K". J. Virol. 69 (1): 141–9. doi:10.1128/JVI.69.1.141-149.1995. PMC   188557 . PMID   7983704.
• Sauter M, Schommer S, Kremmer E, et al. (1995). "Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas". J. Virol. 69 (1): 414–21. doi:10.1128/JVI.69.1.414-421.1995. PMC   188589 . PMID   7983737.
• Zsíros J, Jebbink MF, Lukashov VV, et al. (1998). "Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses". J. Gen. Virol. 79. ( Pt 1): 61–70. doi: 10.1099/0022-1317-79-1-61 . PMID   9460924.
• Andersson ML, Lindeskog M, Medstrand P, et al. (1999). "Diversity of human endogenous retrovirus class II-like sequences". J. Gen. Virol. 80. ( Pt 1): 255–60. doi: 10.1099/0022-1317-80-1-255 . PMID   9934709.
• Berkhout B, Jebbink M, Zsíros J (1999). "Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus". J. Virol. 73 (3): 2365–75. doi:10.1128/JVI.73.3.2365-2375.1999. PMC   104482 . PMID   9971820.
• Barbulescu M, Turner G, Seaman MI, et al. (1999). "Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans". Curr. Biol. 9 (16): 861–8. Bibcode:1999CBio....9..861B. doi: 10.1016/S0960-9822(99)80390-X . PMID   10469592. S2CID   14578723.
• Tönjes RR, Czauderna F, Kurth R (1999). "Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K." J. Virol. 73 (11): 9187–95. doi:10.1128/JVI.73.11.9187-9195.1999. PMC   112952 . PMID   10516026.
• Sugimoto J, Matsuura N, Kinjo Y, et al. (2001). "Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping". Genomics. 72 (2): 137–44. doi:10.1006/geno.2001.6473. PMID   11401426.
• Wang-Johanning F, Frost AR, Jian B, et al. (2003). "Quantitation of HERV-K env gene expression and splicing in human breast cancer". Oncogene. 22 (10): 1528–35. doi:10.1038/sj.onc.1206241. PMID   12629516.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• de Parseval N, Lazar V, Casella JF, et al. (2003). "Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins". J. Virol. 77 (19): 10414–22. doi:10.1128/JVI.77.19.10414-10422.2003. PMC   228468 . PMID   12970426.
• Blaise S, de Parseval N, Bénit L, Heidmann T (2004). "Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 13013–8. Bibcode:2003PNAS..10013013B. doi: 10.1073/pnas.2132646100 . PMC   240736 . PMID   14557543.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi: 10.1038/nature02399 . PMID   15057824.
• Schmutz J, Martin J, Terry A, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 5". Nature. 431 (7006): 268–74. Bibcode:2004Natur.431..268S. doi: 10.1038/nature02919 . PMID   15372022.
• Galli UM, Sauter M, Lecher B, et al. (2005). "Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors". Oncogene. 24 (19): 3223–8. doi:10.1038/sj.onc.1208543. PMID   15735668.
• Mayer J, Stuhr T, Reus K, et al. (2006). "Haplotype analysis of the human endogenous retrovirus locus HERV-K(HML-2.HOM) and its evolutionary implications". J. Mol. Evol. 61 (5): 706–15. doi:10.1007/s00239-005-0066-7. PMID   16211423. S2CID   41436118.
• Romano CM, Ramalho RF, Zanotto PM (2006). "Tempo and mode of ERV-K evolution in human and chimpanzee genomes". Arch. Virol. 151 (11): 2215–28. doi:10.1007/s00705-006-0792-1. PMID   16830071. S2CID   19483207.