Epipodophyllotoxin

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Etoposide, an epipodophyllotoxin Etoposide.svg
Etoposide, an epipodophyllotoxin

Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant ( Podophyllum peltatum ).

Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II. [1]

See also

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References

  1. Takimoto CH, Calvo E. "Principles of Oncologic Pharmacotherapy" Archived 2009-05-15 at the Wayback Machine in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) Cancer Management: A Multidisciplinary Approach Archived 2013-10-04 at the Wayback Machine . 11 ed. 2008.