Eric N. Olson | |
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| Born | September 27, 1955 |
Eric Newell Olson (born September 27, 1955 in Rochester, New York [1] ) is an American molecular biologist. He is professor and chair of the Department of Molecular Biology at the University of Texas Southwestern Medical Center in Dallas, where he also holds the Robert A. Welch Distinguished Chair in Science, the Annie and Willie Nelson Professorship in Stem Cell Research, and the Pogue Distinguished Chair in Research on Cardiac Birth Defects. [2]
Olson grew up in North Carolina and attended Wake Forest University, receiving a B.A. in Chemistry and Biology, and a Ph.D. in Biochemistry. After postdoctoral training at Washington University School of Medicine, he began his scientific career at MD Anderson Cancer Center in Houston. In 1995, he founded the Department of Molecular Biology at UT Southwestern.
Olson and his trainees discovered many of the key genes and mechanisms responsible for development of the heart and other muscles. His laboratory also unveiled the signaling pathways responsible for pathological cardiac growth and heart failure. Olson’s discoveries at the interface of developmental biology and medicine have illuminated the fundamental principles of organ formation and have provided new concepts in the quest for cardiovascular therapeutics. His most recent work has provided a new strategy for correction of Duchenne muscular dystrophy using CRISPR gene editing.
Olson is a member of the U.S. National Academy of Sciences, the National Academy of Medicine, and the American Academy of Arts and Sciences. His work has been recognized by numerous awards, including the Basic Research Prize and Research Achievement Award from the American Heart Association, the Pasarow Medical Research Award, the Pollin Prize, the Passano Award, and the March of Dimes Prize in Developmental Biology. In 2009, the French Academy of Science awarded Dr. Olson the Lefoulon-Delalande Grand Prize for Science. His work has been cited over 200,000 times in the scientific literature. [3]
Olson was awarded the Eugene Braunwald Mentorship Award from the American Heart Association. [4] The International Society for Heart Research also established the Eric N. Olson Mentorship Award in his honor. [5]
Olson serves on the advisory boards of numerous organizations and has founded multiple biotechnology companies to translate the discoveries from his laboratory to the clinic.[ citation needed ] In his spare time, he plays guitar and harmonica with The Transactivators, a rock band inspired by the Texas musician, Willie Nelson, who created the professorship that supports Olson's research. [6]
Howard Robert Horvitz ForMemRS NAS AAA&S APS NAM is an American biologist best known for his research on the nematode worm Caenorhabditis elegans, for which he was awarded the 2002 Nobel Prize in Physiology or Medicine, together with Sydney Brenner and John E. Sulston, whose "seminal discoveries concerning the genetic regulation of organ development and programmed cell death" were "important for medical research and have shed new light on the pathogenesis of many diseases".
The University of Texas Southwestern Medical Center is a public academic health science center in Dallas, Texas. With approximately 23,000 employees, more than 3,000 full-time faculty, and nearly 4 million outpatient visits per year, UT Southwestern is the largest medical school in the University of Texas System and the State of Texas.
Ronald Mark Evans is an American Biologist, Professor and Head of the Salk’s Gene Expression Laboratory, and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute for Biological Studies in La Jolla, California and a Howard Hughes Medical Institute Investigator. Dr. Ronald M. Evans is known for his original discoveries of nuclear hormone receptors (NR), a special class of transcriptional factor, and the elucidation of their universal mechanism of action, a process that governs how lipophilic hormones and drugs regulate virtually every developmental and metabolic pathway in animals and humans. Nowadays, NRs are among the most widely investigated group of pharmaceutical targets in the world, already yielding benefits in drug discovery for cancer, muscular dystrophies, osteoporosis, type II diabetes, obesity, and cardiovascular diseases. His current research focuses on the function of nuclear hormone signaling and their function in metabolism and cancer.
Joseph Leonard Goldstein ForMemRS is an American biochemist. He received the Nobel Prize in Physiology or Medicine in 1985, along with fellow University of Texas Southwestern researcher, Michael Brown, for their studies regarding cholesterol. They discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develop hypercholesterolemia and become at risk for cholesterol related diseases, notably coronary heart disease. Their studies led to the development of statin drugs.
Kevin P. Campbell is an Investigator for the Howard Hughes Medical Institute, UI Foundation Distinguished Professor, the Roy J. Carver Chair of Molecular Physiology and Biophysics, and head of the department; he is also professor of neurology and internal medicine at the University of Iowa.
Eugene Braunwald is an Austrian-born American cardiologist.
Carolyn Widney Greider is an American molecular biologist and Nobel laureate. She joined the University of California, Santa Cruz as a Distinguished Professor in the department of molecular, cell, and developmental biology in October 2020.
Robert Joseph Lefkowitz is an American physician and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University.
Bert W. O’Malley is the Tom Thompson Distinguished Service Professor of Molecular and Cellular Biology and Chancellor at Baylor College of Medicine. A native of Pittsburgh, he has a bachelor's degree from the University of Pittsburgh and a M.D. from their School of Medicine (1963). He completed his residency at Duke University and spent four years at the National Institute of Health followed by four years serving as the Luscious Birch Professor and the director of the Reproductive Biology Center at Vanderbilt University. He then moved to Baylor as Professor and Chairman of Molecular and Cellular Biology.
The Pollin Prize for Pediatric Research was an annual award given to physicians who contributed important advances to the field of pediatrics, and was the only existing international pediatric award. The prize was created in 2002 by Irene and Abe Pollin, and funded by the Linda and Kenneth Pollin Foundation. It was administered by the NewYork-Presbyterian Hospital, and as of 2003, Dr. Rudolph Leibel was chairman of the selection panel.
Thomas Christian Südhof, ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the school of medicine in the department of molecular and cellular physiology, and by courtesy in neurology, and in psychiatry and behavioral sciences at Stanford University.
Stefanie Dimmeler is a German biologist specializing in the pathophysiological processes underlying cardiovascular diseases. Her awards and honours include the Gottfried Wilhelm Leibniz Prize of the German Research Foundation for her work on the programmed cell death of endothelial cells. Since 2008 she has led the Institute for Cardiovascular Regeneration at the University of Frankfurt. Her current work is focusing to develop cellular and pharmacological strategies to improve cardiovascular repair and regeneration. Her work aims to establish non-coding RNAs as novel therapeutic targets.
Joan Massagué, is a Spanish biologist and the current director of the Sloan Kettering Institute at Memorial Sloan Kettering Cancer Center. He is also an internationally recognized leader in the study of both cancer metastasis and growth factors that regulate cell behavior, as well as a professor at the Weill Cornell Graduate School of Medical Sciences.
Nina Starr Braunwald (1928–1992) was an American thoracic surgeon and medical researcher who was among the first women to perform open-heart surgery. She was also the first woman to be certified by the American Board of Thoracic Surgery, and the first to be elected to the American Association for Thoracic Surgery. In 1960, at the age of 32, she led the operative team at the U.S. National Institutes of Health (NIH) that implanted the first successful artificial mitral human heart valve replacement, which she had designed and fabricated. She died in August 1992 in Weston, Massachusetts, after a career that included prominent appointments at the NIH, University of California, San Diego, Harvard Medical School, and Brigham and Women's Hospital.
Rhian M. Touyz Koppel MBBCh, MSc (Med), PhD, FRCP, FRSE, FMedSci, FCAHS is a Canadian medical researcher. She is currently serving as the Executive Director and Chief Scientific Officer of the Research Institute of the McGill University Health Centre in Montreal, Canada, since 2021. A clinician scientist, her research primarily focuses on hypertension and cardiovascular disease.
Robert Roberts, is a cardiologist, geneticist, academic, and medical researcher.
Duojia Pan is a Chinese-American developmental biologist at the University of Texas Southwestern Medical Center, where he is Fouad A. and Val Imm Bashour Distinguished Professor of Physiology, chairman of the department of physiology, and investigator of the Howard Hughes Medical Institute (HHMI). His research is focused on molecular mechanisms of growth control and tissue homeostasis and their implications in human disease.
Christine Edry Seidman is the Thomas W. Smith Professor of Medicine at Harvard Medical School and director of the Cardiovascular Genetics Center at Brigham and Women's Hospital. She operates a joint lab with her husband, Jonathan Seidman, where they study genetic mechanisms of heart disease. In recognition of her scientific contributions, she was elected as a fellow of the National Academy of Sciences, American Academy of Arts and Sciences, and National Academy of Medicine.
Kenneth R. Chien is an American doctor and medical scientist who has been a research director at Karolinska Institute, in Stockholm, since 2013. Chien has several papers with over 1,000 citations and a h-index of 132. His area of expertise is cardiovascular science. His research into regenerative cardiovascular medicine, specifically while director of the Cardiovascular Program of the Harvard Stem Cell Institute, led to his co-founding, in 2010, of ModeRNA Therapeutics. In 2018, the company re-branded as Moderna, Inc. Chien is a recipient of the Walter Bradford Cannon Award of the American Physiology Society and the Pasarow Award. He is a member of the Norwegian Academy of Science and Letters, the Austrian Academy of Sciences, and has received an honorary doctorate from the University of Edinburgh.
James Thornton Willerson was an American cardiologist. He was the President Emeritus, Director of Cardiology Research, and Co-Director of the Cullen Cardiovascular Research Laboratories at the Texas Heart Institute. Upon moving to Houston in 1989, Willerson created the Institute of Molecular Medicine for the Prevention of Human Diseases.
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