Six Degrees of Kevin Bacon or Bacon's Law is a parlor game where players challenge each other to arbitrarily choose an actor and then connect them to another actor via a film that both actors have appeared in together, repeating this process to try to find the shortest path that ultimately leads to prolific American actor Kevin Bacon. It rests on the assumption that anyone involved in the Hollywood film industry can be linked through their film roles to Bacon within six steps. The game's name is a reference to "six degrees of separation", a concept that posits that any two people on Earth are six or fewer acquaintance links apart.
Fat Albert and the Cosby Kids is an American animated television series created, produced, and hosted by comedian Bill Cosby, who also lent his voice to a number of characters, including Fat Albert himself. Filmation was the production company for the series. The show premiered in 1972 and aired until 1985. The show, based on Cosby's remembrances of his childhood gang, focused on Fat Albert, and his friends.
Robin Hood is a 1973 American animated musical adventure comedy film produced by Walt Disney Productions and released by Buena Vista Distribution. Produced and directed by Wolfgang Reitherman, it is based on the English folktale "Robin Hood". The story follows the adventures of Robin Hood, Little John, and the inhabitants of Nottingham as they fight against the excessive taxation of Prince John, and Robin Hood wins the hand of Maid Marian. The film features the voices of Brian Bedford, Phil Harris, Peter Ustinov, Pat Buttram, Monica Evans, Terry-Thomas, Roger Miller, and Carole Shelley.
Little Bill is an American animated educational television series created by Bill Cosby. It is based on the Little Bill book series, written by Cosby with illustrations by Varnette P. Honeywood. Cosby also composed some of the theme music, appeared in live-action in the show's intro sequence, and voiced the recurring character of Captain Brainstorm. It was Cosby's second animated series, after Fat Albert and the Cosby Kids.
Here Comes Garfield is a 1982 animated television special based on the comic strip Garfield by Jim Davis. It was the first half-hour Garfield TV special. It is directed by Phil Roman and features Lorenzo Music as the voice of Garfield the house cat, as well as the voices of Sandy Kenyon, Henry Corden and Gregg Berger.
A person's Erdős–Bacon number is the sum of one's Erdős number—which measures the "collaborative distance" in authoring academic papers between that person and Hungarian mathematician Paul Erdős—and one's Bacon number—which represents the number of links, through roles in films, by which the person is separated from American actor Kevin Bacon. The lower the number, the closer a person is to Erdős and Bacon, which reflects a small world phenomenon in academia and entertainment.
The Batman/Superman Hour is a Filmation animated series that was broadcast on CBS from 1968 to 1969. Premiering on September 14, 1968, this 60-minute program featured new adventures of the DC Comics superheroes Batman, Robin and Batgirl alongside shorts from The New Adventures of Superman and The Adventures of Superboy.
p14ARF is an alternate reading frame protein product of the CDKN2A locus. p14ARF is induced in response to elevated mitogenic stimulation, such as aberrant growth signaling from MYC and Ras (protein). It accumulates mainly in the nucleolus where it forms stable complexes with NPM or Mdm2. These interactions allow p14ARF to act as a tumor suppressor by inhibiting ribosome biogenesis or initiating p53-dependent cell cycle arrest and apoptosis, respectively. p14ARF is an atypical protein, in terms of its transcription, its amino acid composition, and its degradation: it is transcribed in an alternate reading frame of a different protein, it is highly basic, and it is polyubiquinated at the N-terminus.
Mitogen-activated protein kinase 1, also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.
Cbl is a mammalian gene family. CBL gene, a part of the Cbl family, encodes the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Mutations to this gene have been implicated in a number of human cancers, particularly acute myeloid leukaemia.
Receptor tyrosine-protein kinase erbB-3, also known as HER3, is a membrane bound protein that in humans is encoded by the ERBB3 gene.
Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene.
Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene.
Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. Two mRNAs from the gene have been identified that encode proteins of 1335 and 1177 amino acids long.
Potassium channel subfamily K member 9 is a protein that in humans is encoded by the KCNK9 gene.
Ras and Rab interactor 1 is a protein that in humans is encoded by the RIN1 gene.
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) also known as islet cell autoantigen-related protein (ICAAR) and phogrin is an enzyme that in humans is encoded by the PTPRN2 gene. PTPRN and PTPRN2 are both found to be major autoantigens associated with insulin-dependent diabetes mellitus.
Calcium modulating ligand, also known as calcium-modulating cyclophilin ligand, is a signalling protein recognized by the TNF receptor TACI.
Matrix metallopeptidase 27 also known as MMP-27 is an enzyme which in humans is encoded by the MMP27 gene.
Hugh David Politzer is an American theoretical physicist and the Richard Chace Tolman Professor of Theoretical Physics at the California Institute of Technology. He shared the 2004 Nobel Prize in Physics with David Gross and Frank Wilczek for their discovery of asymptotic freedom in quantum chromodynamics.
