Peer review is the evaluation of work by one or more people with similar competences as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review methods are used to maintain quality standards, improve performance, and provide credibility. In academia, scholarly peer review is often used to determine an academic paper's suitability for publication. Peer review can be categorized by the type of activity and by the field or profession in which the activity occurs, e.g., medical peer review.
A medical journal is a peer-reviewed scientific journal that communicates medical information to physicians and other health professionals. Journals that cover many medical specialties are sometimes called general medical journals.
A molecule is an electrically neutral group of two or more atoms held together by chemical bonds. Molecules are distinguished from ions by their lack of electrical charge. However, in quantum physics, organic chemistry, and biochemistry, the term molecule is often used less strictly, also being applied to polyatomic ions.
The journal evaluates molecules, signal pathways, receptors and other therapeutic targets and their potential as candidates for drug development. Articles in this journal focus on the molecular level and should not include clinical information on specific drugs
The audience consists of scientists, managers and decision makers in the pharmaceutical industry, academic researchers working in the field of molecular medicine and others closely involved in R&D.
The journal is published by Informa. The Editor in Chief of the journal is Professor Daniele Santini, University Campus Bio-Medico, Rome, Italy
Informa plc is a multinational events and publishing company with its head office and registered office in London. It has offices in 43 countries and around 11,000 employees. It owns numerous brands including CRC Press, Datamonitor, Fan Expo, Institute for International Research, Lloyd's List, Penton, Routledge, Taylor & Francis, and UBM.
Indexing
Expert Opinion on Therapeutic Targets ranks #25 of 261 in the Pharmacology & Pharmacy category in the 2017 ISI Journal Citation Reports. The journal has a 2017 impact factor of 4.598.
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index which reflects the yearly average number of citations to recent articles published in that journal. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factors are often deemed to be more important than those with lower ones. The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI). Impact factors are calculated yearly starting from 1975 for journals listed in the Journal Citation Reports (JCR).
Index Medicus (IM) is a curated subset of MEDLINE, which is a bibliographic database of life science and biomedical science information, principally scientific journal articles. From 1879 to 2004, Index Medicus was a comprehensive bibliographic index of such articles in the form of a print index or its onscreen equivalent. Medical history experts have said of Index Medicus that it is “America's greatest contribution to medical knowledge.”
MEDLINE is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care. MEDLINE also covers much of the literature in biology and biochemistry, as well as fields such as molecular evolution.
Pharmacology is the branch of biology concerned with the study of drug or medication action, where a drug can be broadly defined as any man-made, natural, or endogenous molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
The Institute for Scientific Information (ISI) was an academic publishing service, founded by Eugene Garfield in Philadelphia in 1960. ISI offered scientometric and bibliographic database services. Its specialty was citation indexing and analysis, a field pioneered by Garfield.
Isis is a quarterly peer-reviewed academic journal published by the University of Chicago Press. It covers the history of science, history of medicine, and the history of technology, as well as their cultural influences. It contains original research articles and extensive book reviews and review essays. Furthermore, sections devoted to one particular topic are published in each issue in open access. These sections consist of the Focus section, the Viewpoint section and the Second Look section.
The Bulletin of the American Mathematical Society is a quarterly mathematical journal published by the American Mathematical Society.
A coactivator is a type of transcriptional coregulator that binds to an activator to increase the rate of transcription of a gene or set of genes. The activator contains a DNA binding domain that binds either to a DNA promoter site or a specific DNA regulatory sequence called an enhancer. Binding of the activator-coactivator complex increases the speed of transcription by recruiting general transcription machinery to the promoter, therefore increasing gene expression. The use of activators and coactivators allows for highly specific expression of certain genes depending on cell type and developmental stage.
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor. Receptor sites have specific affinities for drugs based on the chemical structure of the drug, as well as the specific action that occurs there. Drugs that do not bind to receptors produce their corresponding therapeutic effect by simply interacting with chemical or physical properties in the body. Common examples of drugs that work in this way are antacids and laxatives.
The Journal of Endocrinology is a monthly peer-reviewed scientific journal that publishes original research articles, reviews and commentaries. Its focus is on endocrine physiology and metabolism, including hormone secretion, hormone action and biological effects. The journal considers basic and translational studies at the organ and whole organism level.
Expert Opinion on Pharmacotherapy is a peer-reviewed medical journal publishing review articles and original papers on new pharmacotherapies. It is published by Informa and the editor-in-chief is Dimitri P. Mikhailidis.
Expert Opinion on Biological Therapy is a monthly peer-reviewed medical journal covering research on all aspects of biological therapy, including gene therapy and gene transfer technologies, therapeutic peptides and proteins, vaccines and antibodies, and cell- and tissue-based therapies. The journal is published by Taylor & Francis and the editor-in-chief is Michael Morse. The journal was established in 2001 and according to the Journal Citation Reports, it has a 2017 impact factor of 3.974. The journal is also indexed in MEDLINE.
Expert Opinion on Therapeutic Patents is a monthly peer-reviewed medical journal covering pharmaceutical patent information across all therapy areas. Each review includes an "expert opinion" section, in which authors provide their personal view on the current status and future direction of the research discussed. The journal was established in 1991 and is published by Informa. The editor-in-chief is Claudiu T. Supuran.
Expert Opinion on Drug Delivery is a monthly peer-reviewed medical journal publishing review articles covering all aspects of research on drug delivery, from initial concept to potential therapeutic application and final relevance in clinical use. It was established in 2004 and is published by Taylor and Francis Group. The editor-in-chief is Uday Kompella.
Expert Opinion on Drug Safety is a monthly peer-reviewed medical journal publishing review articles on all aspects of pharmacovigilance and original papers on the clinical implications of drug treatment safety issues. It was established in 2002 and is published by Informa. The editor-in-chief is Roger McIntyre.
Expert Opinion on Drug Metabolism & Toxicology is a monthly peer-reviewed medical journal publishing review articles on ADME-Tox. It was established in 2005 and is published by Taylor and Francis. The editor-in-chief is Luis Valerio.
Expert Opinion on Drug Discovery is a monthly peer-reviewed medical journal publishing review articles on novel technologies involved in drug discovery. The editor-in-chief David Janero.
Current Cancer Drug Targets is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Ruiwen Zhang. The journal covers research on contemporary molecular drug targets involved in cancer, including medicinal chemistry, pharmacology, molecular biology, genomics, and biochemistry. Current Cancer Drug Targets publishes original research reports, review papers, and rapid communications ("letters").
Selurampanel is a drug closely related to the quinoxalinedione series which acts as a competitive antagonist of the AMPA and kainate receptors and, as of 2015, is being investigated in clinical trials by Novartis for the treatment of epilepsy. It has also been studied in the acute treatment of migraine, and was found to produce some pain relief, but with a relatively high rate of side effects.
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