Extracorporeal shockwave therapy

Last updated
Extracorporeal shockwave therapy
Gerat zur extrakorporalen Stosswellentherapie.JPG
ESWT device (EMS Swiss DolorClast)
ICD-10-PCS 6A93
ICD-9-CM 98.5
ESWT device Fokussiertes Stosswellen-System.jpg
ESWT device

Extracorporeal shockwave therapy (ESWT) is a treatment using powerful acoustic pulses which is mostly used to treat kidney stones and in physical therapy and orthopedics. [1] [2]

Contents

Medical uses

Some of the passed fragments of a 1-cm calcium oxalate stone that was smashed using lithotripsy Kidney stone fragments.png
Some of the passed fragments of a 1-cm calcium oxalate stone that was smashed using lithotripsy

The most common use of extracorporeal shockwave therapy (ESWT) is for lithotripsy to treat kidney stones [3] (urinary calculosis) and biliary calculi (stones in the gallbladder or in the liver) using an acoustic pulse. It is also reported to be used for salivary stones [4] and pancreatic stones. [5]

In the UK, the National Institute for Health and Care Excellence (NICE) found that the evidence for ESWT in the majority of indications is conflicting, and therefore ESWT should only be used where there are special arrangements for clinical governance and audit. [6] Two 2017 reviews had similar findings, with moderate level evidence at best. [7] [8]

Extracorporeal shockwave therapy is used as a second line measure to treat tennis elbow, [9] [10] shoulder rotator cuff pain, [11] [12] Achilles tendinitis, [13] [14] plantar fasciitis, [15] [16] and greater trochanteric pain syndrome. [17]

ESWT is also used to promote bone healing and treat bone necrosis. [18] It is an effective alternative to surgical treatment of non-healing fractures. [19]

ESWT is used for wound healing and has shown positive results in short-term and long-term outcomes in diabetic patients with foot ulcers. [20] Randomised controlled trials into the use of ESWT for healing venous leg ulcers are needed as there is a lack of evidence in this area. [21]

Low-intensity extracorporeal shock wave therapy has been used as a treatment for erectile dysfunction. [22] It differs from palliative options by aiming to restore natural erectile function by inducing cellular microtrauma, triggering the release of angiogenic factors and promoting neovascularization in treated tissue. This mechanism is distinct from the high-intensity shock waves used in lithotripsy and medium-intensity shock waves used for anti-inflammatory purposes in orthopedics. Clinical studies, including double-blind randomized trials, have demonstrated LI-ESWT's ability to significantly improve erectile function and penile hemodynamics in men with vasculogenic ED. [23] [24]

Procedure

The lithotripter attempts to break up the stone with minimal collateral damage by using an externally applied, focused, high-intensity acoustic pulse. The patient is usually sedated or anesthetized for the procedure in order to help them remain still and reduce possible discomfort. [25] Sedation is not required in its application for soft tissue injuries.

History

Beginning in 1969 and funded by the German Ministry of Defense, Dornier began a study of the effects of shock waves on tissue. In 1972, on the basis of preliminary studies performed by Dornier Medical Systems, an agreement was reached with Egbert Schmiedt, director of the urologic clinic at the University of Munich. The development of the Dornier lithotripter progressed through several prototypes, ultimately culminating in February 1980 with the first treatment of a human by shockwave lithotripsy (SWL). The production and distribution of the Dornier HM3 lithotripter began in late 1983, and SWL was approved by the U.S. Food and Drug Administration in 1984. [26]

In the 1980s people using ESWT for kidney stones noticed that it appeared to increase bone density in nearby bones, leading them to explore it for orthopedic purposes. [27]

Research

In response to concerns raised by NICE, in 2012 a study called the Assessment of the Effectiveness of ESWT for Soft Tissue Injuries was launched (ASSERT). [6]

As of 2018 use of ESWT had been studied as a potential treatment for chronic prostatitis/chronic pelvic pain syndrome in three small studies; there were short-term improvements in symptoms and few adverse effects, but the medium-term results are unknown, and the results are difficult to generalize due to the low quality of the studies. [28]

Veterinary use

ESWT is commonly used for treating orthopedic problems in horses, including tendon and ligament injuries, kissing spine, navicular syndrome, and arthritis. The evidence for these uses is weak. [27]

Physiotherapy use

ESWT is used in physical therapy for pain reduction, increase in metabolism at the cellular level, revascularisation, and recovering normal muscle tone following various disorders. [29] The use of ESWT was demonstrated in patients with frozen shoulders compared to therapeutic ultrasound with exercises. [30]

Research suggests that ESWT can accelerate the blood flow, facilitating the healing of the inflamed Achilles tendon.[ citation needed ] In one study involving 23 patients with chronic Achilles tendinopathy, 20 reported improvement in their condition and pain scores after ESWT; three saw no change, and none reported any worsening. [31]

See also

Related Research Articles

Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity. It is the most common sexual problem in males and can cause psychological distress due to its impact on self-image and sexual relationships.

<span class="mw-page-title-main">Kidney stone disease</span> Formation of mineral stones in the urinary tract

Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material develops in the urinary tract. Renal calculi typically form in the kidney and leave the body in the urine stream. A small calculus may pass without causing symptoms. If a stone grows to more than 5 millimeters, it can cause blockage of the ureter, resulting in sharp and severe pain in the lower back that often radiates downward to the groin. A calculus may also result in blood in the urine, vomiting, or painful urination. About half of people who have had a renal calculus are likely to have another within ten years.

<span class="mw-page-title-main">Tendinopathy</span> Inflammation of the tendon

Tendinopathy is a type of tendon disorder that results in pain, swelling, and impaired function. The pain is typically worse with movement. It most commonly occurs around the shoulder, elbow, wrist, hip, knee, or ankle.

<span class="mw-page-title-main">Gallstone</span> Disease where stones form in the gallbladder

A gallstone is a stone formed within the gallbladder from precipitated bile components. The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, and choledocholithiasis refers to the presence of migrated gallstones within bile ducts.

<span class="mw-page-title-main">Plantar fasciitis</span> Connective tissue disorder of the heel

Plantar fasciitis or plantar heel pain is a disorder of the plantar fascia, which is the connective tissue that supports the arch of the foot. It results in pain in the heel and bottom of the foot that is usually most severe with the first steps of the day or following a period of rest. Pain is also frequently brought on by bending the foot and toes up towards the shin. The pain typically comes on gradually, and it affects both feet in about one-third of cases.

<span class="mw-page-title-main">Tennis elbow</span> Condition in which the outer part of the elbow becomes sore and tender

Tennis elbow, also known as lateral epicondylitis or enthesopathy of the extensor carpi radialis origin, is an enthesopathy of the origin of the extensor carpi radialis brevis on the lateral epicondyle. Those with tennis elbow often report pain and tenderness over the bony prominence of the lateral epicondyle, which serves as the common origin of the forearm and hand’s long extensor tendons. Symptoms range from mild tenderness to severe, persistent pain. The pain may also extend into the back of the forearm. Onset of symptoms is generally gradual, although they can seem sudden and be misinterpreted as an injury.

<span class="mw-page-title-main">Achilles tendinitis</span> Medical condition of the ankle and heel

Achilles tendinitis, also known as Achilles tendinopathy, is soreness of the Achilles tendon. It is accompanied by alterations in the tendon's structure and mechanical properties. The most common symptoms are pain and swelling around the back of the ankle. The pain is typically worse at the start of exercise and decreases thereafter. Stiffness of the ankle may also be present. Onset is generally gradual.

<span class="mw-page-title-main">Chronic pancreatitis</span> Medical condition

Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions. It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption. It is a disease process characterized by irreversible damage to the pancreas as distinct from reversible changes in acute pancreatitis. Tobacco smoke and alcohol misuse are two of the most frequently implicated causes, and the two risk factors are thought to have a synergistic effect with regards to the development of chronic pancreatitis. Chronic pancreatitis is a risk factor for the development of pancreatic cancer.

Lithotripsy is a procedure involving the physical destruction of hardened masses like kidney stones, bezoars or gallstones, which may be done non-invasively. The term is derived from the Greek words meaning "breaking stones".

An extracorporeal procedure is a medical procedure which is performed outside the body. Extracorporeal devices are the artificial organs that remain outside the body while treating a patient. Extracorporeal devices are useful in hemodialysis and cardiac surgery.

<span class="mw-page-title-main">Shin splints</span> Inflammation of the inner edge of the shin bone (tibia)

A shin splint, also known as medial tibial stress syndrome, is pain along the inside edge of the shinbone (tibia) due to inflammation of tissue in the area. Generally this is between the middle of the lower leg and the ankle. The pain may be dull or sharp, and is generally brought on by high-impact exercise that overloads the tibia. It generally resolves during periods of rest. Complications may include stress fractures.

Prolotherapy, also called proliferation therapy, is an injection-based treatment used in chronic musculoskeletal conditions. It has been characterised as an alternative medicine practice.

<span class="mw-page-title-main">Renal colic</span> Severe abdominal pain due to obstruction of the ureter, often from kidney stones

Renal colic, also known as ureteric colic, is a type of abdominal pain commonly caused by obstruction of ureter from dislodged kidney stones. The most frequent site of obstruction is the vesico-ureteric junction (VUJ), the narrowest point of the upper urinary tract. Acute obstruction and the resultant urinary stasis can distend the ureter (hydroureter) and cause a reflexive peristaltic smooth muscle spasm, which leads to a very intense visceral pain transmitted via the ureteric plexus.

<span class="mw-page-title-main">Patellar tendinitis</span> Human disease

Patellar tendinitis, also known as jumper's knee, is an overuse injury of the tendon that straightens the knee. Symptoms include pain in the front of the knee. Typically the pain and tenderness is at the lower part of the kneecap, though the upper part may also be affected. Generally there is no pain when the person is at rest. Complications may include patellar tendon rupture.

Therapeutic effect refers to the response(s) after a treatment of any kind, the results of which are judged to be useful or favorable. This is true whether the result was expected, unexpected, or even an unintended consequence. An adverse effect is the converse and refers to harmful or undesired response(s). What constitutes a therapeutic effect versus a side effect is a matter of both the nature of the situation and the goals of treatment. No inherent difference separates therapeutic and undesired side effects; both responses are behavioral/physiologic changes that occur as a response to the treatment strategy or agent.

<span class="mw-page-title-main">Calcific tendinitis</span> Disorder characterized by calcium deposits in a tendon

Calcific tendinitis is a common condition where deposits of calcium phosphate form in a tendon, sometimes causing pain at the affected site. Deposits can occur in several places in the body, but are by far most common in the rotator cuff of the shoulder. Around 80% of those with deposits experience symptoms, typically chronic pain during certain shoulder movements, or sharp acute pain that worsens at night. Calcific tendinitis is typically diagnosed by physical exam and X-ray imaging. The disease often resolves completely on its own, but is typically treated with non-steroidal anti-inflammatory drugs to relieve pain, rest and physical therapy to promote healing, and in some cases various procedures to breakdown and/or remove the calcium deposits.

<span class="mw-page-title-main">Low-level laser therapy</span> Treatment using irradiation with light of low power intensity

Low-level laser therapy (LLLT), cold laser therapy, photobiomodulation (PBM) or red light therapy is a form of medicine that applies low-level (low-power) lasers or light-emitting diodes (LEDs) to the surface of the body. Whereas high-power lasers are used in laser medicine to cut or destroy tissue, it is claimed that application of low-power lasers relieves pain or stimulates and enhances cell function. The effects appear to be limited to a specified set of wavelengths and new research has demonstrated effectiveness at myopia control. Several such devices are cleared by the United States Food and Drug Administration (FDA), and research shows potential for treating a range of medical problems including rheumatoid arthritis and oral mucositis.

<span class="mw-page-title-main">Platelet-rich plasma</span> Blood product used in transfusion medicine

Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of plasma protein derived from whole blood, centrifuged to remove red blood cells but retaining platelets. Though promoted for treating various medical conditions, evidence of its benefits was mixed as of 2020, showing effectiveness in certain conditions and ineffectiveness in others.

<span class="mw-page-title-main">Non-invasive procedure</span> Medical procedure involving no break in skin

A medical procedure is defined as non-invasive when no break in the skin is created and there is no contact with the mucosa, or skin break, or internal body cavity beyond a natural or artificial body orifice. For example, deep palpation and percussion are non-invasive but a rectal examination is invasive. Likewise, examination of the ear-drum or inside the nose or a wound dressing change all fall outside the definition of non-invasive procedure. There are many non-invasive procedures, ranging from simple observation, to specialised forms of surgery, such as radiosurgery. Extracorporeal shock wave lithotripsy is a non-invasive treatment of stones in the kidney, gallbladder or liver, using an acoustic pulse. For centuries, physicians have employed many simple non-invasive methods based on physical parameters in order to assess body function in health and disease, such as pulse-taking, the auscultation of heart sounds and lung sounds, temperature examination, respiratory examination, peripheral vascular examination, oral examination, abdominal examination, external percussion and palpation, blood pressure measurement, change in body volumes, audiometry, eye examination, and many others.

Electrohydraulic Lithotripsy (EHL) is a medical procedure which uses targeted shockwaves to break up kidney stones and gallstones. This form of extracorporeal lithotripsy is unique in that the shockwaves are produced by a vaporization bubble expanding and collapsing repeatedly, creating a pressure wave. The procedure is non-invasive and has a 90% success rate, which makes it a first-line treatment for smaller kidney stones.

References

  1. Wang, Ching-Jen (2012). "Extracorporeal shockwave therapy in musculoskeletal disorders". Journal of Orthopaedic Surgery and Research. 7 (1): 11. doi: 10.1186/1749-799X-7-11 . PMC   3342893 . PMID   22433113.
  2. Chung, Bryan; Wiley, J. Preston (2002). "Extracorporeal Shockwave Therapy". Sports Medicine. 32 (13): 851–865. doi:10.2165/00007256-200232130-00004. PMID   12392445. S2CID   30387795.
  3. Setthawong V, Srisubat A, Potisat S, Lojanapiwat B, Pattanittum P (August 2023). "Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) for kidney stones". The Cochrane Database of Systematic Reviews. 2023 (8): CD007044. doi:10.1002/14651858.CD007044.pub4. PMC   10392035 . PMID   37526261.
  4. "Salivary duct stones". MedlinePlus Medical Encyclopedia. U.S. National Library of Medicine.
  5. Hayes JM, Ding SL (September 2012). "Pancreatic stone and treatment using ERCP and ESWL procedures: a case study and review". The New Zealand Medical Journal. 125 (1361): 89–97. PMID   22960720.
  6. 1 2 Maffulli G, Hemmings S, Maffulli N (September 2014). "Assessment of the Effectiveness of Extracorporeal Shock Wave Therapy (ESWT) For Soft Tissue Injuries (ASSERT): An Online Database Protocol". Translational Medicine @ UniSa. 10: 46–51. PMC   4140430 . PMID   25147767.
  7. Korakakis V, Whiteley R, Tzavara A, Malliaropoulos N (March 2018). "The effectiveness of extracorporeal shockwave therapy in common lower limb conditions: a systematic review including quantification of patient-rated pain reduction". British Journal of Sports Medicine. 52 (6): 387–407. doi: 10.1136/bjsports-2016-097347 . PMID   28954794.
  8. Steuri R, Sattelmayer M, Elsig S, Kolly C, Tal A, Taeymans J, Hilfiker R (September 2017). "Effectiveness of conservative interventions including exercise, manual therapy and medical management in adults with shoulder impingement: a systematic review and meta-analysis of RCTs". British Journal of Sports Medicine. 51 (18): 1340–1347. doi:10.1136/bjsports-2016-096515. PMC   5574390 . PMID   28630217.
  9. "Extracorporeal shockwave therapy for refractory tennis elbow". Interventional procedures guidance. National Institute for Health and Clinical Excellence. August 2009. IPG313.
  10. Thiele S, Thiele R, Gerdesmeyer L (December 2015). "Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy". International Journal of Surgery. 24 (Pt B): 165–170. doi: 10.1016/j.ijsu.2015.09.034 . PMID   26455532.
  11. "Extracorporeal shockwave lithotripsy for calcific tendonitis (tendinopathy) of the shoulder". Interventional procedures guidance. National Institute for Health and Clinical Excellence. November 2003. IPG21.
  12. Louwerens JK, Sierevelt IN, van Noort A, van den Bekerom MP (August 2014). "Evidence for minimally invasive therapies in the management of chronic calcific tendinopathy of the rotator cuff: a systematic review and meta-analysis". Journal of Shoulder and Elbow Surgery. 23 (8): 1240–1249. doi:10.1016/j.jse.2014.02.002. PMID   24774621.
  13. "Extracorporeal shockwave therapy for refractory Achilles tendinopathy". Interventional procedures guidance. National Institute for Health and Clinical Excellence. August 2009. IPG312.[ needs update ]
  14. Wiegerinck JI, Kerkhoffs GM, van Sterkenburg MN, Sierevelt IN, van Dijk CN (June 2013). "Treatment for insertional Achilles tendinopathy: a systematic review". Knee Surgery, Sports Traumatology, Arthroscopy. 21 (6): 1345–1355. doi:10.1007/s00167-012-2219-8. PMID   23052113. S2CID   2214735.
  15. "Extracorporeal shockwave therapy for refractory plantar fasciitis". Interventional procedures guidance. National Institute for Health and Clinical Excellence. August 2009. IPG311.
  16. Yin MC, Ye J, Yao M, Cui XJ, Xia Y, Shen QX, et al. (August 2014). "Is extracorporeal shock wave therapy clinical efficacy for relief of chronic, recalcitrant plantar fasciitis? A systematic review and meta-analysis of randomized placebo or active-treatment controlled trials". Archives of Physical Medicine and Rehabilitation. 95 (8): 1585–1593. doi:10.1016/j.apmr.2014.01.033. PMID   24662810.
  17. "Extracorporeal shockwave therapy for refractory greater trochanteric pain syndrome". Interventional procedures guidance. National Institute for Health and Clinical Excellence. January 2011. IPG376.
  18. Cheng JH, Wang CJ (December 2015). "Biological mechanism of shockwave in bone". International Journal of Surgery. 24 (Pt B): 143–146. doi: 10.1016/j.ijsu.2015.06.059 . PMID   26118613.
  19. Kong FR, Liang YJ, Qin SG, Li JJ, Li XL (January 2010). "[Clinical application of extracorporeal shock wave to repair and reconstruct osseous tissue framework in the treatment of avascular necrosis of the femoral head (ANFH)]". Zhongguo Gu Shang = China Journal of Orthopaedics and Traumatology (in Chinese). 23 (1): 12–15. PMID   20191955.
  20. Wang CJ, Cheng JH, Kuo YR, Schaden W, Mittermayr R (December 2015). "Extracorporeal shockwave therapy in diabetic foot ulcers". International Journal of Surgery. 24 (Pt B): 207–209. doi: 10.1016/j.ijsu.2015.06.024 . PMID   26079500.
  21. Cooper B, Bachoo P (June 2018). "Extracorporeal shock wave therapy for the healing and management of venous leg ulcers". The Cochrane Database of Systematic Reviews. 2018 (6): CD011842. doi:10.1002/14651858.CD011842.pub2. PMC   6513251 . PMID   29889978.
  22. "Low-intensity extracorporeal shockwave therapy for erectile dysfunction: an overview of systematic reviews". Translational Andrology and Urology. 2024-10-09. Retrieved 2024-10-09.
  23. Bocchino, Alessia Celeste; Pezzoli, Marta; Martínez-Salamanca, Juan Ignacio; Russo, Giorgio Ivan; Lo Giudice, Arturo; Cocci, Andrea (March 2023). "Low-intensity extracorporeal shock wave therapy for erectile dysfunction: Myths and realities". Investigative and Clinical Urology. 64 (2): 118–125. doi:10.4111/icu.20220327. ISSN   2466-0493. PMC   9995960 . PMID   36882170.
  24. Gruenwald, Ilan; Appel, Boaz; Kitrey, Noam D.; Vardi, Yoram (April 2013). "Shockwave treatment of erectile dysfunction". Therapeutic Advances in Urology. 5 (2): 95–99. doi:10.1177/1756287212470696. ISSN   1756-2872. PMC   3607492 . PMID   23554844.
  25. "Lithotrypsy" National Kidney Foundation, Accessed February 6, 2017
  26. "Gastroenterology and Urology Devices; Reclassification of the Extracorporeal Shock Wave Lithotripter AGENCY: Food and Drug Administration, HHS ACTION: Proposed rule". Federal Register (US Government). February 8, 1999. Retrieved February 6, 2017.
  27. 1 2 Chamberlain GA, Colborne GR (2016). "A review of the cellular and molecular effects of extracorporeal shockwave therapy". Veterinary and Comparative Orthopaedics and Traumatology. 29 (2): 99–107. doi:10.3415/VCOT-15-04-0057. PMID   26846274. S2CID   19280257. Open Access logo PLoS transparent.svg
  28. Franco JV, Turk T, Jung JH, Xiao YT, Iakhno S, Garrote V, Vietto V (May 2018). "Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome". The Cochrane Database of Systematic Reviews. 2018 (5): CD012551. doi:10.1002/14651858.CD012551.pub3. PMC   6494451 . PMID   29757454.
  29. Gündüz R, Malas FÜ, Borman P, Kocaoğlu S, Özçakar L (May 2012). "Physical therapy, corticosteroid injection, and extracorporeal shock wave treatment in lateral epicondylitis. Clinical and ultrasonographical comparison". Clinical Rheumatology. 31 (5): 807–812. doi:10.1007/s10067-012-1939-y. PMID   22278162. S2CID   13109216.
  30. Muthukrishnan R, Rashid AA, Al-Alkharji F (July 2019). "The effectiveness of extracorporeal shockwave therapy for frozen shoulder in patients with diabetes: randomized control trial". Journal of Physical Therapy Science. 31 (7): 493–497. doi:10.1589/jpts.31.493. PMC   6642889 . PMID   31417208.
  31. Fridman R, Cain JD, Weil L, Weil L (November–December 2008). "Extracorporeal shockwave therapy for the treatment of Achilles tendinopathies: a prospective study". Journal of the American Podiatric Medical Association. 98 (6): 466–468. doi:10.7547/0980466. PMID   19017855.