FTH1P5

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Ferritin, heavy polypeptide 1 pseudogene 5 is a protein that in humans is encoded by the FTH1P5 gene. [1]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Related Research Articles

Pseudogene functionless relative of a gene

Pseudogenes, sometimes referred to as zombie genes in the media, are segments of DNA that are related to real genes. Pseudogenes have lost at least some functionality, relative to the complete gene, in cellular gene expression or protein-coding ability. Pseudogenes often result from the accumulation of multiple mutations within a gene whose product is not required for the survival of the organism, but can also be caused by genomic copy number variation (CNV) where segments of 1+ kb are duplicated or deleted. Although not fully functional, pseudogenes may be functional, similar to other kinds of noncoding DNA, which can perform regulatory functions. The "pseudo" in "pseudogene" implies a variation in sequence relative to the parent coding gene, but does not necessarily indicate pseudo-function. Despite being non-coding, many pseudogenes have important roles in normal physiology and abnormal pathology.

Ferritin

Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion. The protein is produced by almost all living organisms, including algae, bacteria, higher plants, and animals. In humans, it acts as a buffer against iron deficiency and iron overload. Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body, hence serum ferritin is used as a diagnostic test for iron-deficiency anemia.

Pituitary adenylate cyclase-activating peptide protein-coding gene in the species Homo sapiens

Pituitary adenylate cyclase-activating polypeptide also known as PACAP is a protein that in humans is encoded by the ADCYAP1 gene. PACAP is similar to vasoactive intestinal peptide. One of its effects is to stimulate enterochromaffin-like cells. It binds to vasoactive intestinal peptide receptor and to the PACAP receptor.

Gastric inhibitory polypeptide receptor protein-coding gene in the species Homo sapiens

The gastric inhibitory polypeptide receptor (GIP-R), also known as the glucose-dependent insulinotropic polypeptide receptor, is a protein that in humans is encoded by the GIPR gene. GIP-R is a member of the 7-transmembrane protein family, a class of G protein–coupled receptors. GIP-R is found on beta-cells in the pancreas.

Neuropeptide Y receptor Y6 pseudogene in the species Homo sapiens

Putative neuropeptide Y receptor type 6 is a protein that in humans is encoded by the NPY6R gene.

<i>RHCE</i> (gene) protein-coding gene in the species Homo sapiens

Blood group Rh(CE) polypeptide is a protein that in humans is encoded by the RHCE gene. RHCE has also recently been designated CD240CE.

ATP1A2 protein-coding gene in the species Homo sapiens

ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide, also known as ATP1A2, is a protein which in humans is encoded by the ATP1A2 gene.

Ferritin light chain protein-coding gene in the species Homo sapiens

Ferritin light chain is a protein that in humans is encoded by the FTL gene.

Small nuclear ribonucleoprotein polypeptide C protein-coding gene in the species Homo sapiens

U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene.

COX7A2 protein-coding gene in the species Homo sapiens

Cytochrome c oxidase polypeptide 7A2, mitochondrial is an enzyme that in humans is encoded by the COX7A2 gene.

MYL6 protein-coding gene in the species Homo sapiens

Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene.

COX6A1 protein-coding gene in the species Homo sapiens

Cytochrome c oxidase subunit 6A1, mitochondrial is a protein that in humans is encoded by the COX6A1 gene. Cytochrome c oxidase 6A1 is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain. A mutation of the COX6A1 gene is associated with a recessive axonal or mixed form of Charcot-Marie-Tooth disease.

UDP glucuronosyltransferase 1 family, polypeptide A cluster, also known as UGT1A@, is a human gene.

FTH1 protein-coding gene in the species Homo sapiens

Ferritin heavy chain is a ferroxidase enzyme that in humans is encoded by the FTH1 gene.

POLR2J2 protein-coding gene in the species Homo sapiens

DNA directed RNA polymerase II polypeptide J-related gene, also known as POLR2J2, is a human gene.

CYP26C1 protein-coding gene in the species Homo sapiens

CYP26C1 is a protein which in humans is encoded by the CYP26C1gene.

CYP2A7 protein-coding gene in the species Homo sapiens

CYP2A7 is a protein that in humans is encoded by the CYP2A7 gene.

UGT1A8 protein-coding gene in the species Homo sapiens

UDP-glucuronosyltransferase 1-8 is an enzyme that in humans is encoded by the UGT1A8 gene.

<i>UGT1A7</i> (gene) protein-coding gene in the species Homo sapiens

UDP glucuronosyltransferase 1 family, polypeptide A7 is a protein that in humans is encoded by the UGT1A7 gene.

Ferritin heavy chain 1 pseudogene 3 is a protein that in humans is encoded by the FTH1P3 gene.

References

  1. ↑ "Entrez Gene: Ferritin, heavy polypeptide 1 pseudogene 5" . Retrieved 2015-02-16.

Further reading

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