Faggot cells are cells normally found in the hypergranular form of acute promyelocytic leukemia (FAB - M3). These promyelocytes (not blast cells) have numerous Auer rods in the cytoplasm which gives the appearance of a bundle of sticks, from which the cells are given their name. [1] [2]
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include natural killer cells, T cells, and B cells. They are the main type of cell found in lymph, which prompted the name "lymphocyte". Lymphocytes make up between 18% and 42% of circulating white blood cells.
Type I hypersensitivity is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen. Type I is distinct from type II, type III and type IV hypersensitivities.
An immunogen is any substance that generates B-cell (humoral/antibody) and/or T-cell (cellular) adaptive immune responses upon exposure to a host organism. Immunogens that generate antibodies are called antigens ("antibody-generating"). Immunogens that generate antibodies are directly bound by host antibodies and lead to the selective expansion of antigen-specific B-cells. Immunogens that generate T-cells are indirectly bound by host T-cells after processing and presentation by host antigen-presenting cells.
The lingual tonsils are a collection of lymphatic tissue located in the lamina propria of the root of the tongue. This lymphatic tissue consists of the lymphatic nodules rich in cells of the immune system (immunocytes). The immunocytes initiate the immune response when the lingual tonsils get in contact with invading microorganisms.
Crenation in botany and zoology, describes an object's shape, especially a leaf or shell, as being round-toothed or having a scalloped edge.
A direct fluorescent antibody, also known as "direct immunofluorescence", is an antibody that has been tagged in a direct fluorescent antibody test. Its name derives from the fact that it directly tests the presence of an antigen with the tagged antibody, unlike western blotting, which uses an indirect method of detection, where the primary antibody binds the target antigen, with a secondary antibody directed against the primary, and a tag attached to the secondary antibody.
Allan Jay Lichtman is an American historian who has taught at American University in Washington, D.C. since 1973.
The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by G-CSF and other cytokines triggers maturation, differentiation, proliferation and cell survival.
Lymphoproliferative disorders (LPDs) refer to a specific class of diagnoses, comprising a group of several conditions, in which lymphocytes are produced in excessive quantities. These disorders primarily present in patients who have a compromised immune system. Due to this factor, there are instances of these conditions being equated with "immunoproliferative disorders"; although, in terms of nomenclature, lymphoproliferative disorders are a subclass of immunoproliferative disorders—along with hypergammaglobulinemia and paraproteinemias.
Co-stimulation is a secondary signal which immune cells rely on to activate an immune response in the presence of an antigen-presenting cell. In the case of T cells, two stimuli are required to fully activate their immune response. During the activation of lymphocytes, co-stimulation is often crucial to the development of an effective immune response. Co-stimulation is required in addition to the antigen-specific signal from their antigen receptors.
Jeffrey Harris Lichtman is a New York-based criminal defense lawyer.
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name hemopoietin receptors, and share a common amino acid motif (WSXWS) in the extracellular portion adjacent to the cell membrane. Members of the type I cytokine receptor family comprise different chains, some of which are involved in ligand/cytokine interaction and others that are involved in signal transduction.
The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis.
Understanding of the antitumor immunity role of CD4+ T cells has grown substantially since the late 1990s. CD4+ T cells (mature T-helper cells) play an important role in modulating immune responses to pathogens and tumor cells, and are important in orchestrating overall immune responses.
Brainbow is a process by which individual neurons in the brain can be distinguished from neighboring neurons using fluorescent proteins. By randomly expressing different ratios of red, green, and blue derivatives of green fluorescent protein in individual neurons, it is possible to flag each neuron with a distinctive color. This process has been a major contribution to the field of neural connectomics.
The Keys to the White House is a prediction system for determining the outcome of presidential elections in the United States. It was developed by American historian Allan Lichtman and Russian geophysicist Vladimir Keilis-Borok in 1981, adapting prediction methods that Keilis-Borok designed for earthquake prediction. The system is a thirteen-point checklist that concerns the circumstances of a presidential election. When five or fewer items on the checklist are false, the incumbent party candidate is predicted to win the election. Some of the items on this checklist involve qualitative judgment, and therefore the reliability of this system relies heavily on the knowledge and analytical skill of whoever attempts to apply it. Using his own system, Lichtman has correctly predicted the outcomes of all presidential elections from 1984 to 2020, with the exception of the 2000 election.
Dean J. Copely, Jr. is an American former competitive Ice Dancer. With Charlotte Lichtman, he is the 2011 World Junior Ice Dance Bronze Medalist and 2011 U.S. Junior Ice Dance Champion.
Cassidy Lichtman is an American female volleyball player. She was part of the United States women's national volleyball team from 2011 to 2016.
The Case for Impeachment is a non-fiction book by American University Distinguished Professor of History Allan Lichtman arguing for the impeachment of Donald Trump. It was published on April 18, 2017, by Dey Street Books, an imprint of HarperCollins. Lichtman predicted to The Washington Post that after ascending to the presidency, Trump would later be impeached from office. He developed this thesis into a set of multiple arguments for Trump's predicted impeachment.
Jeff W. Lichtman is an American neuroscientist. He is the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of Arts and Sciences at Harvard University. He is best known for his pioneering work developing the neuroimaging connectomic technique known as Brainbow.