Fatigue (disambiguation)

Last updated January 21, 2026

Fatigue is a subjective feeling of tiredness or exhaustion or loss of energy in humans.

Medical

Central nervous system fatigue, changes in the synaptic concentration of neurotransmitters which affects exercise performance and muscle function
- Synaptic fatigue
Chronic fatigue, long-term fatigue that limits a person's energy or ability to carry out daily activities, also known as central fatigue
Cancer-related fatigue, a side effect of chemotherapy, radiation therapy, and biotherapy
Compassion fatigue, a lessening of compassion common among those who work with trauma victims
Muscle fatigue, the decline in ability of a muscle to generate force, also known as peripheral fatigue
Battle fatigue/Combat fatigue, an outdated term for:
- Combat stress reaction, a military term for short-term behavioral disorganization
- Post-traumatic stress disorder, a medical term for a long-term disorder
Effects of fatigue on safety in transportation and shift work
- Pilot fatigue
- Sleep-deprived driving

Fatigue (material), the initiation and propagation of cracks in a material due to cyclic loading
Voter fatigue, public apathy about elections
Information fatigue, impairment caused by excessive information
Fatigue (safety), implications of tiredness in many fields, especially transportation
Fatigue (album), a 2021 album by L'Rain.
Fatigue Mountain, on the border of Alberta and British Columbia, Canada
Fatigue duty, work assigned to military men that does not require the use of armament.