Fort Sherman virus

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Fort Sherman virus
Virus classification OOjs UI icon edit-ltr.svg
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Peribunyaviridae
Genus: Orthobunyavirus
Species:
Virus:
Fort Sherman virus

Fort Sherman virus (FSV) [1] is a single-stranded, negative sense, tri-segmented RNA virus. The virus is an isolate of Bunyamwera virus (BUNV) and closely related to Cache Valley virus (CVV). There are multiple strains of the virus, each with individual characteristics including the Panama, Brazil, and Argentina strains. Of the three strains, the Panama strain is the only reassortment of them. Research suggests reassortment during the genealogy of the Panama strain. This was found while analyzing the M segment of the virus in which the Brazil and Argentina strains closely matched while the Panama strain matched closely with CVV. The L and S segments matched closely for all three strains. [1]

Contents

Transmission

Three different species have been found to contain Fort Sherman virus which are humans, horses, and mosquitos. [1] Currently, it is unknown whether the divergent South American strains of the virus are able to be transmitted to humans. [1]

Symptoms

Symptoms in humans include fever, muscle pain, sore throat, and malaise. [2]

Geography

Fort Sherman virus is found in a geographic range of more than 7,000 km, solely in South America. Countries containing the virus include Panama, Brazil, and Argentina. [1]

History

The Fort Sherman virus was first isolated in 1985 by Joseph A. Mangiafico from a 36 year-old male US soldier in Panama. [2]

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<i>Orthohantavirus</i> Genus of viruses

Orthohantavirus is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family Hantaviridae within the order Bunyavirales. Members of this genus may be called orthohantaviruses or simply hantaviruses.

<i>Influenza A virus</i> Species of virus

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<span class="mw-page-title-main">Antigenic shift</span> Process by which two or more different strains of a virus combine to form a new subtype

Antigenic shift is the process by which two or more different strains of a virus, or strains of two or more different viruses, combine to form a new subtype having a mixture of the surface antigens of the two or more original strains. The term is often applied specifically to influenza, as that is the best-known example, but the process is also known to occur with other viruses, such as visna virus in sheep. Antigenic shift is a specific case of reassortment or viral shift that confers a phenotypic change.

<span class="mw-page-title-main">Influenza A virus subtype H5N1</span> Subtype of influenza A virus

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<i>Bunyavirales</i> Order of RNA viruses

Bunyavirales is an order of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. It is the only order in the class Ellioviricetes. The name Bunyavirales derives from Bunyamwera, where the original type species Bunyamwera orthobunyavirus was first discovered. Ellioviricetes is named in honor of late virologist Richard M. Elliott for his early work on bunyaviruses.

<span class="mw-page-title-main">Swine influenza</span> Infection caused by influenza viruses endemic to pigs

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<span class="mw-page-title-main">Influenza A virus subtype H3N2</span> Virus subtype

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The Argentine brown bat, is a bat species from South and Central America.

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<span class="mw-page-title-main">Influenza</span> Infectious disease, often just "the flu"

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Batai orthobunyavirus (BATV) is a RNA virus belonging to order Bunyavirales, genus Orthobunyavirus.

Cache Valley orthobunyavirus (CVV) is a member of the order Bunyavirales, genus Orthobunyavirus, and serogroup Bunyamwera, which was first isolated in 1956 from Culiseta inornata mosquitos collected in Utah's Cache Valley. CVV is an enveloped arbovirus, nominally 80–120 nm in diameter, whose genome is composed of three single-stranded, negative-sense RNA segments. The large segment of related bunyaviruses is approximately 6800 bases in length and encodes a probable viral polymerase. The middle CVV segment has a 4463-nucleotide sequence and the smallest segment encodes for the nucleocapsid, and a second non-structural protein. CVV has been known to cause outbreaks of spontaneous abortion and congenital malformations in ruminants such as sheep and cattle. CVV rarely infects humans, but when they are infected it has caused encephalitis and multiorgan failure.

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References

  1. 1 2 3 4 5 Filho, Edmilson F. de Oliveira; Carneiro, Ianei O.; Ribas, Jorge R. L.; Fischer, Carlo; Marklewitz, Marco; Junglen, Sandra; Netto, Eduardo Martins; Franke, Carlos Roberto; Drexler, Jan Felix (2020). "Identification of animal hosts of Fort Sherman virus, a New World zoonotic orthobunyavirus". Transboundary and Emerging Diseases. 67 (4): 1433–1441. doi: 10.1111/tbed.13499 . ISSN   1865-1682. PMID   32009301. S2CID   211015008.
  2. 1 2 "ArboCat Virus: Fort Sherman (FSV)". wwwn.cdc.gov. Retrieved 2022-01-07.